<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies indicated the protective effects of TQ against neurotoxic agents. The present study was aimed to highlight the protective effects of TQ against neurotoxic agents. For this reason, the literature from 1998 to 2017 regarding the protective effects of TQ against neurotoxic agents and their involvement mechanisms has been studied. The present review suggests the protective effects of TQ against neurotoxic agents in experimental models. More clinical trial studies are however needed to confirm the antidotal effects of TQ in human intoxication.</p></abstract>

Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies indicated the protective effects of TQ against neurotoxic agents. The present study was aimed to highlight the protective effects of TQ against neurotoxic agents. For this reason, the literature from 1998 to 2017 regarding the protective effects of TQ against neurotoxic agents and their involvement mechanisms has been studied. The present review suggests the protective effects of TQ against neurotoxic agents in experimental models. More clinical trial studies are however needed to confirm the antidotal effects of TQ in human intoxication.

Antidotal effects of thymoquinone against neurotoxic agents

Innovative Medical Research Center, Faculty of Medicine, Mashhad Branch

Interdisciplinary Toxicology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Antidotal effects of thymoquinone against neurotoxic agents"}

Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies...

Antidotal effects of thymoquinone against neurotoxic agents

Publié en ligne: 02 mars 2019

Pages: 122 - 128

Reçu: 22 déc. 2017

Accepté: 23 janv. 2018

DOI: https://doi.org/10.2478/intox-2018-0008

Mots clés
thymoquinone, neurotoxic agents, antioxidant, antidote

© 2018 Interdisciplinary Toxicology, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Antidotal effects of thymoquinone against neurotoxic agents

Publié en ligne: 02 mars 2019

Pages: 122 - 128

Reçu: 22 déc. 2017

Accepté: 23 janv. 2018

DOI: https://doi.org/10.2478/intox-2018-0008

Mots clésthymoquinone, neurotoxic agents, antioxidant, antidote

© 2018 Interdisciplinary Toxicology, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
thymoquinone, neurotoxic agents, antioxidant, antidote