<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies indicated the protective effects of TQ against neurotoxic agents. The present study was aimed to highlight the protective effects of TQ against neurotoxic agents. For this reason, the literature from 1998 to 2017 regarding the protective effects of TQ against neurotoxic agents and their involvement mechanisms has been studied. The present review suggests the protective effects of TQ against neurotoxic agents in experimental models. More clinical trial studies are however needed to confirm the antidotal effects of TQ in human intoxication.</p></abstract>

Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies indicated the protective effects of TQ against neurotoxic agents. The present study was aimed to highlight the protective effects of TQ against neurotoxic agents. For this reason, the literature from 1998 to 2017 regarding the protective effects of TQ against neurotoxic agents and their involvement mechanisms has been studied. The present review suggests the protective effects of TQ against neurotoxic agents in experimental models. More clinical trial studies are however needed to confirm the antidotal effects of TQ in human intoxication.

Antidotal effects of thymoquinone against neurotoxic agents

Innovative Medical Research Center, Faculty of Medicine, Mashhad Branch

Interdisciplinary Toxicology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Antidotal effects of thymoquinone against neurotoxic agents"}

Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies...

Antidotal effects of thymoquinone against neurotoxic agents

Publicado en línea: 02 mar 2019

Páginas: 122 - 128

Recibido: 22 dic 2017

Aceptado: 23 ene 2018

DOI: https://doi.org/10.2478/intox-2018-0008

Palabras clave
thymoquinone, neurotoxic agents, antioxidant, antidote

© 2018 Interdisciplinary Toxicology, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Antidotal effects of thymoquinone against neurotoxic agents

Publicado en línea: 02 mar 2019

Páginas: 122 - 128

Recibido: 22 dic 2017

Aceptado: 23 ene 2018

DOI: https://doi.org/10.2478/intox-2018-0008

Palabras clavethymoquinone, neurotoxic agents, antioxidant, antidote

© 2018 Interdisciplinary Toxicology, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Palabras clave
thymoquinone, neurotoxic agents, antioxidant, antidote