How polymorphisms of the cytochrome P450 genes affect ibuprofen and diclofenac metabolism and toxicity / Kako polimorfizmi gena citokroma P450 utječu na metabolizam i toksičnost ibuprofena i diklofenaka

Online veröffentlicht: 15. Apr. 2016

Seitenbereich: 1 - 8

Eingereicht: 01. Dez. 2015

Akzeptiert: 01. März 2016

DOI: https://doi.org/10.1515/aiht-2016-67-2754

Schlüsselwörter

adverse effects, allelic variants, CYP2C8, CYP2C9, drug metabolism, gastrointestinal bleeding, genotyping, hepatotoxicity, pharmacogenetics, pharmacogenomics, pharmacokinetics

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