How polymorphisms of the cytochrome P450 genes affect ibuprofen and diclofenac metabolism and toxicity / Kako polimorfizmi gena citokroma P450 utječu na metabolizam i toksičnost ibuprofena i diklofenaka

Published Online: Apr 15, 2016

Page range: 1 - 8

Received: Dec 01, 2015

Accepted: Mar 01, 2016

DOI: https://doi.org/10.1515/aiht-2016-67-2754

Keywords

adverse effects, allelic variants, CYP2C8, CYP2C9, drug metabolism, gastrointestinal bleeding, genotyping, hepatotoxicity, pharmacogenetics, pharmacogenomics, pharmacokinetics

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