[Alexiou P, Pegklidou K, Chatzopoulou M, Nicolaou I, Demopoulos VJ. (2009). Aldose reductase enzyme and its implication to major health problems of the 21(st) century. Curr Med Chem 16: 734-752.]Search in Google Scholar
[Artik N. (1998). Determination of phenolic compounds in pomegranate juice by using HPLC. Fruit Processing 8: 492-499]Search in Google Scholar
[Bagri P, Ali M, Aeri V, Bhowmik M, Sultana S. (2009). Antidiabetic effect of Punica granatum flowers: effect on hyperlipidemia, pancreatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes. Food Chem Toxicol 47: 50-54.]Search in Google Scholar
[Bell C, Hawthorne S. (2008). Ellagic acid, pomegranate and prostate cancer - a mini review. J Pharm Pharmacol 60: 139-144.]Search in Google Scholar
[Blois, M. S. (1958). Antioxidant determinations by the use of a stable free radical. Nature 181: 1199-1200.]Search in Google Scholar
[Cerda B, Espin JC, Parra S, Martinez P, Tomas-Barberan FA. (2004). The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healthy humans. Eur J Nutr 43: 205-220.]Search in Google Scholar
[Chidambara Murthy KN, Jayaprakasha GK, Singh RP. (2002). Studies on antioxidant activity of pomegranate (Punica granatum) peel extract using in vivo models. J Agric Food Chem 50: 4791-4795.]Search in Google Scholar
[Constantino L, Rastelli G, Gamberini MC et al., (1999). 1-Benzopyran-4-one antioxidants and aldose reductase inhibitors. J Med Chem 42: 1881-1893.]Search in Google Scholar
[Coudert P, Albuisson E, Boire JY, Duroux E, Bastide P, Couquelet J. (1994). Synthesis of pyridazine acetic acid derivatives possessing aldose reductase inhibitory activity and antioxidant properties. Eur J Med Chem 29: 471-477.]Search in Google Scholar
[Das AK, Mandal SC, Banerjee SK, Sinha S, Saha BP, Pal M. (2001). Studies on the hypoglycaemic activity of Punica granatum seed in streptozotocin induced diabetic rats. Phytother Res 15: 628-629.]Search in Google Scholar
[Da Settimo F, Primofiore G, La Motta C, Sartini S, Taliani S, Simorini F, Marini AM, Lavecchia A, Novellino E, Boldrini E. (2005). Naphtho[1,2-d]isothiazole acetic acid derivatives as a novel class of selective aldose reductase inhibitors. J Med Chem 48: 6897-907.]Search in Google Scholar
[Del Corso A, Cappiello M, Mura U. (2008). From a dull enzyme to something else: facts and perspectives regarding aldose reductase. Curr Med Chem 15: 1452-1461.]Search in Google Scholar
[Dikmen M, Ozturk N, Ozturk Y. (2011). The antioxidant potency of Punica granatum L. Fruit peel reduces cell proliferation and induces apoptosis on breast cancer. J Med Food 14:1638-46.]Search in Google Scholar
[El Kar C, Ferchichi A, Attia F, Bouajila J. (2011). Pomegranate (Punica granatum) juices: chemical composition, micronutrient cations, and antioxidant capacity. J Food Sci 76: C795-C800.]Search in Google Scholar
[Gil MI, Tomas-Barberan FA, Hess-Pierce B, Holcroft DM, Kader AA. (2000). Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric Food Chem 48: 4581-4589.]Search in Google Scholar
[Hamada Y, Araki N, Horiuchi S, Hotta N. (1996). Role of polyol pathway in nonenzymatic glycation. Nephrol Dial Transplant 11 (Suppl): 95-98.]Search in Google Scholar
[Hayman S, Kinoshita JH. (1965). Isolation and properties of lens aldose reductase. J Biol Chem 240: 877-882.]Search in Google Scholar
[Han DH, Lee MJ, Kim JH. (2006). Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Research 26: 3601-3606.]Search in Google Scholar
[Hontecillas R, O'Shea M, Einerhand A, Diguardo M, Bassaganya-Riera J. (2009). Activation of PPAR gamma and alpha by punicic acid ameliorates glucose tolerance and suppresses obesity-related inflammation. J Am Coll Nutr 28: 184-195.]Search in Google Scholar
[Huang TH, Peng G, Kota BP, Li GQ, Yamahara J, Roufogalis BD, Li Y. (2005). Anti-diabetic action of Punica granatum flower extract: activation of PPAR-gamma and identification of an active component. Toxicol Appl Pharmacol 207: 160-169.]Search in Google Scholar
[Jafri MA, Aslam M, Javed K, Singh S. (2000). Effect of Punica granatum Linn. (flowers) on blood glucose level in normal and alloxan-induced diabetic rats. Journal of Ethnopharmacology 70: 309-314.]Search in Google Scholar
[Joseph MM, Aravind SR, Varghese S, Mini S, Sreelekha TT. (2011). Evaluation of antioxidant, antitumor and immunomodulatory properties of polysaccharide isolated from fruit rind of Punica granatum. Mol Med Report doi: 10.3892/mmr.2011.638. [Epub ahead of print].10.3892/mmr.2011.63822012001]Search in Google Scholar
[Juranek I, Horakova L, Rackova L, Stefek M. (2009). Antioxidants in treating pathologies involving oxidative damage: an update on medicinal chemistry and biological activity of stobadine and related pyridoindoles. Curr Med Chem 17: 552-570.]Search in Google Scholar
[Jurenka JS. (2008). Therapeutic applications of pomegranate (Punica granatum L.): a review. Altern Med Rev. 13: 128-144.]Search in Google Scholar
[Kador PF. (1998). The role of aldose reductase in the development of diabetic complications. Med Res Rev 8: 325-352.]Search in Google Scholar
[Kador PF, Lee JW, Fujisawa S, Blessing K, Lou MF. (2000). Relative importance of aldose reductase versus nonenzymatic glycosylation on sugar cataract formation in diabetic rats. J Ocul Pharmacol Ther 16: 149-160.]Search in Google Scholar
[Katz SR, Newman RA, Lansky EP. (2007). Punica granatum: heuristic treatment for diabetes mellitus. J Med Food 10: 213-217.]Search in Google Scholar
[Kinoshita JH. (1990). A thirty-year journey in the polyol pathway. Exp Eye Res 50: 567-573.]Search in Google Scholar
[Kyselova Z, Stefek M, Bauer V. (2004). Pharmacological prevention of diabetic cataract. J Diabetes Complications 18: 129-140.]Search in Google Scholar
[Kulkarni AP, Aradhya SM, Divakar S. (2004). Isolation and identification of a radical scavenging antioxidant-punicalagin from pith and carpellary membrane of pomegranate fruit. Food Chem 87: 551-557.]Search in Google Scholar
[Lansky EP. (2006). Beware of pomegranates bearing 40% ellagic acid. J Med Food 9: 119-122.]Search in Google Scholar
[Lansky EP, Newmana RA. (2007). Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer. Journal of Ethnopharmacology 109: 177-206.]Search in Google Scholar
[Li Y, Qi Y, Huang TH, Yamahara J, Roufogalis BD. (2008). Pomegranate flower: a unique traditional antidiabetic medicine with dual PPAR-alpha/-gamma activator properties. Diabetes Obes Metab 10: 10-17.]Search in Google Scholar
[Li Y, Wen S, Kota BP, Peng G, Li GQ, Yamahara J, Roufogalis BD. (2005). Punica granatum flower extract, a potent alpha-glucosidase inhibitor, improves postprandial hyperglycemia in Zucker diabetic fatty rats. J Ethnopharmacol 99: 239-244.]Search in Google Scholar
[Mihaljevic B, Katusin-Razem B, Razem B. (1996). The reevaluation of the ferric thiocyanate assay for lipid hydroperoxides with special considerations of the mechanistic aspects of the response. Free Radic Biol Med 21: 53.]Search in Google Scholar
[Naz S, Siddiqi R, Ahmad S, Rasool SA, Sayeed SA. (2007). Antibacterial activity directed isolation of compounds from Punica granatum. J Food Sci 72: M341-M345.]Search in Google Scholar
[Negi PS, Jayaprakasha GK, Jena BS. (2003). Antioxidant and antimutagenic activities of pomegranate peel extracts. Food Chemistry 80: 393-397.]Search in Google Scholar
[Oates PJ. (2008). Aldose reductase, still a compelling target for diabetic neuropathy. Curr Drug Targets 9: 14-36.]Search in Google Scholar
[Obrosova IG. (2005). Increased sorbitol pathway activity generates oxidative stress in tissue sites for diabetic complications. Antioxid Redox Signal 7: 1543-1552.]Search in Google Scholar
[Rout S, Banerjee R. (2007). Free radical scavenging, anti-glycation and tyrosinase inhibition properties of a polysaccharide fraction isolated from the rind from Punica granatum. Bioresour Technol 98: 3159-3163.]Search in Google Scholar
[Scott JA, King GL. (2004). Oxidative stress and antioxidant treatment in diabetes. Ann N Y Acad Sci 1031: 204-213.]Search in Google Scholar
[Seeram NP, Adams LS, Henning SM, Niu Y, Zhang Y, Nair MG, Heber D. (2005). In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 16: 360-367.]Search in Google Scholar
[Singh RP, Chidambara Murthy KN, Jayaprakasha GK. (2002). Studies on the antioxidant activity of pomegranate (Punica granatum) peel and seed extracts using in vitro models. J Agric Food Chem 50: 81-86.]Search in Google Scholar
[Stefek M. (2011). Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract. Interdisc Toxicol 4: 101-109.]Search in Google Scholar
[Stefek M, Karasu C. (2011). Eye lens in aging and diabetes. Effect of quercetin. Rejuvenation Research 14: 525-534.]Search in Google Scholar
[Stefek M, Snirc V, Djoubissie PO, Majekova M, Demopoulos V, Rackova L, Bezakova Z, Karasu C, Carbone V, El-Kabbani O. (2008). Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling. Bioorg Med Chem 16: 4908-4920.]Search in Google Scholar
[Sun Hui, Jia Dong-ying, Yao Kai. (2008). inhibitory effect of polyphenol extract from pomegranate peel on aldose reductase activity. Natural Product Research And Development 20 (3): 508-510.]Search in Google Scholar
[Ueda H, Kawanishi K, Moriyasu M. (2004). Effects of ellagic acid and 2-(2,3,6-trihydroxy-4-carboxyphenyl)ellagic acid on sorbitol accumulation in vitro and in vivo Biol. Pharm Bull 27: 1584-1587.]Search in Google Scholar
[Walid Elfalleh, Nizar Tlili, Nizar Nasri, Yassine Yahia, Hedia Hannachi, Nizar Chaira, Ma Ying, Ali Ferchichi. (2011). Antioxidant capacities of phenolic compounds and tocopherols from tunisian pomegranate (Punica granatum). Fruits Journal of Food Science 76: C707-C713.]Search in Google Scholar
[Wang R, Ding Y, Liu R, Xiang L, Du L. (2010). Pomegranate: constituents, bioactivities and pharmacokinetics. fruit, Vegetable and Cereal Science and Biotechnology Special Issue 2: 77-87.]Search in Google Scholar
[Yabe-Nishimura C. (1998). Aldose reductase in glucose toxicity: a potential target for the prevention of diabetic complications. Pharmacol Rev 50: 21-33.]Search in Google Scholar
[Zahin M, Aqil F, Ahmad I. (2010). Broad spectrum antimutagenic activity of antioxidant active fraction of punica granatum L. peel extracts. Mutat Res 703: 99-107.]Search in Google Scholar
