<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Multiwalled carbon nanotubes (MWCNTs) have attracted huge attention due to their multifunctionality. Their unique properties allows for covalent and noncovalent modifications. The most simple method for functionalization of carbon nanotubes is their decoration with the oxygen containing moieties which can be further simultaneously functionalized for design of new class carriers for targeting and imaging. Here, we present methodology for chopping nanotubes, characterization of MWCNTs, the effect of size on the biocompatibility in culture of L929 mouse fibroblasts using WST-1, LDH and apoptosis assays. The analysis provides the optimal carbon nanotubes length and concentration which can be used for functionalization in order to minimize the effect of the secondary agglomeration when interacting with cells.</p></abstract>

Multiwalled carbon nanotubes (MWCNTs) have attracted huge attention due to their multifunctionality. Their unique properties allows for covalent and noncovalent modifications. The most simple method for functionalization of carbon nanotubes is their decoration with the oxygen containing moieties which can be further simultaneously functionalized for design of new class carriers for targeting and imaging. Here, we present methodology for chopping nanotubes, characterization of MWCNTs, the effect of size on the biocompatibility in culture of L929 mouse fibroblasts using WST-1, LDH and apoptosis assays. The analysis provides the optimal carbon nanotubes length and concentration which can be used for functionalization in order to minimize the effect of the secondary agglomeration when interacting with cells.

Carbon nanotubes with controlled length – preparation, characterization and their cytocompatibility effects

West Pomeranian University of Technology Szczecin

Nanomaterials Physicochemistry Department, Faculty of Technology and Chemical Engineering

Polish Journal of Chemical Technology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Multiwalled carbon nanotubes (MWCNTs) have attracted huge attention due to their multifunctionality. Their unique properties allows for covalent and...

Carbon nanotubes with controlled length – preparation, characterization and their cytocompatibility effects

Published Online: Jul 25, 2018

Page range: 71 - 79

DOI: https://doi.org/10.2478/pjct-2018-0025

Keywords
Multiwalled carbon nanotubes, cutting carbon nanotubes, size effect, mitochondrial activity, biocompatibility, apoptosis, necrosis

© 2018 Krzysztof Cendrowski et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Carbon nanotubes with controlled length – preparation, characterization and their cytocompatibility effects

Published Online: Jul 25, 2018

Page range: 71 - 79

DOI: https://doi.org/10.2478/pjct-2018-0025

KeywordsMultiwalled carbon nanotubes, cutting carbon nanotubes, size effect, mitochondrial activity, biocompatibility, apoptosis, necrosis

© 2018 Krzysztof Cendrowski et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Multiwalled carbon nanotubes, cutting carbon nanotubes, size effect, mitochondrial activity, biocompatibility, apoptosis, necrosis