Solubility enhancement of atorvastatin by embedding in micro sized carrier

1. Panghal D, Nagpal M, Thakur GS, Arora S. Dissolution Improvement of Atorvastatin Calcium using Modified Locust Bean Gum by the Solid Dispersion Technique. Scientia pharmaceutica. 2013;82(1):177-91.10.3797/scipharm.1301-23395122824634850Search in Google Scholar

2. Lau YY, Okochi H, Huang Y, Benet LZ. Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin singel doses: relevance of first pass effect from hepatic uptake transposrtes, and intestinal and hepatic metabolism. Drug Metabolism and Disposition. 2006;34(7):1175-81.10.1124/dmd.105.00907616624870Search in Google Scholar

3. Prabhu P, Patravale V. Dissolution enhancement of atorvastatin calcium by co-grinding technique. Drug delivery and translational research. 2016;6(4):380-91.Search in Google Scholar

4. Rodde MS, Divase GT, Devkar TB, Tekade AR. Solubility and Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin: In Vitro, Ex Vivo, and In Vivo Studies. BioMed Research International. 2014;2014:10.10.1155/2014/463895406568024995297Search in Google Scholar

5. Han L, Li M, Liu Y, Han C, Ye P. Atorvastatin May Delay Cardiac Aging by Upregulating Peroxisome Proliferator-Activated Receptors in Rats. Pharmacology. 2012;89(1-2):74-82.10.1159/00033578322343316Search in Google Scholar

6. Ahmed IS, El Hosary R, Hassan MA, Haider M, Abd-Rabo MM. Efficacy and Safety Profiles of Oral Atorvastatin-Loaded Nanoparticles: Effect of Size Modulation on Biodistribution. Molecular pharmaceutics. 2018;15(1):247-55.10.1021/acs.molpharmaceut.7b0085629232954Search in Google Scholar

7. Chen Z-g, Cai H-j, Jin X, Lu J-h, Wang J, Fang N-y. Effects of atorvastatin on bone mineral density (BMD) and bone metabolism in elderly males with osteopenia and mild dyslipidemia: A 1-year randomized trial. Archives of Gerontology and Geriatrics. 2014;59(3):515-21.10.1016/j.archger.2014.07.00625131773Search in Google Scholar

8. McGown CC, Brookes ZLS, Hellewell PG, Ross JJ, Brown NJ. Atorvastatin reduces endotoxin-induced microvascular inflammation via NOSII. Naunyn-Schmiedeberg’s Archives of Pharmacology. 2015;388(5):557-64.10.1007/s00210-015-1100-y25678054Search in Google Scholar

9. Ahmed IS, El-Hosary R, Shalaby S, Abd-Rabo MM, Elkhateeb DG, Nour S. PD-PK evaluation of freeze-dried atorvastatin calcium-loaded poly-epsilon-caprolactone nanoparticles. International journal of pharmaceutics. 2016;504(1-2):70-9.10.1016/j.ijpharm.2016.03.04527021467Search in Google Scholar

10. Yao GT, Song LP, Xue WH, Su GH, Ning AH, Wang J. Nano-particle engineered atorvastatin delivery to support mesenchymal stem cell survival in infarcted myocardium. Saudi journal of biological sciences. 2018;25(6):1016-21.10.1016/j.sjbs.2017.03.015611743530174496Search in Google Scholar

11. Mathur M, Devi Vemula K. Investigation of different types of nano drug delivery systems of atorvastatin for the treatment of hyperlipidemia. Drug development and industrial pharmacy. 2018;44(12):2048-60.10.1080/03639045.2018.150822530073852Search in Google Scholar

12. Thenmozhi S, Dharmaraj N, Kadirvelu K, Kim HY. Electrospun nanofibers: New generation materials for advanced applications. Materials Science and Engineering: B. 2017;217:36-48.10.1016/j.mseb.2017.01.001Search in Google Scholar

13. Xue J, Xie J, Liu W, Xia Y. Electrospun Nanofibers: New Concepts, Materials, and Applications. Accounts of Chemical Research. 2017;50(8):1976-87.10.1021/acs.accounts.7b00218658909428777535Search in Google Scholar

14. Ignatious F, Sun L, Lee C-P, Baldoni J. Electrospun Nanofibers in Oral Drug Delivery. Pharmaceutical Research. 2010;27(4):576-88.10.1007/s11095-010-0061-620143253Search in Google Scholar

15. Cozza ES, Monticelli O, Marsano E, Cebe P. On the elect-rospinning of PVDF: influence of the experimental conditions on the nanofiber properties. Polymer International. 2013;62(1):41-8.10.1002/pi.4314Search in Google Scholar

16. Desai S, Disouza J, Sable A, Hosmani A. Development of Orodispersible Tablet of Atorvastatin Calcium Using Hot Melt Extrusion. Drug Delivery Letters. 2015;5(1):19-30.10.2174/2210303104666141029233757Search in Google Scholar

17. Székely-szentmiklósi B, Hancu G, Székely-szentmiklósi I, Kovács B, Kelemen H. Simultaneous determination of atorvastatin and ezetimibe from combined pharmaceutical products by micellar electrokinetic capillary chromatography. Brazilian Journal of Pharmaceutical sciences. 2017;53(1):e16122.10.1590/s2175-97902017000116122Search in Google Scholar

18. Shete G, Puri V, Kumar L, Bansal A. Solid state characterization of commercial crystalline and amorphous atorvastatin calcium samples. AAPS PharmSciTech. 2010;11(2):588-609.10.1208/s12249-010-9419-7290231920352531Search in Google Scholar