Molecular detection and genetic diversity of porcine circovirus type 3 in commercial pig farms in Xinjiang province, China

1Collins P.J., McKillen J., Allan G.: Porcine circovirus type 3 in the UK. Vet Rec 2017, 181, 599. doi: 10.1136/vr.j5505. Collins P.J. McKillen J. Allan G. Porcine circovirus type 3 in the UK Vet Rec 2017 181 599 10.1136/vr.j5505Open DOISearch in Google Scholar

2Dee S.A., Bauermann F.V., Niederwerder M.C., Singrey A., Clement T., de Lima M., Long C., Patterson G., Sheahan M.A., Stoian A.M.M., Petrovan V., Jones C.K., De Jong J., Ji J., Spronk G.D., Minion L., Christopher-Hennings J., Zimmerman J.J., Rowland R.R.R., Nelson E., Sundberg P., Diel D.G.: Survival of viral pathogens in animal feed ingredients under transboundary shipping models. PLoS One 2018, 13, e0194509. doi: 10.1371/journal.pone.0194509. Dee S.A. Bauermann F.V. Niederwerder M.C. Singrey A. Clement T. de Lima M. Long C. Patterson G. Sheahan M.A. Stoian A.M.M. Petrovan V. Jones C.K. De Jong J. Ji J. Spronk G.D. Minion L. Christopher-Hennings J. Zimmerman J.J. Rowland R.R.R. Nelson E. Sundberg P. Diel D.G. Survival of viral pathogens in animal feed ingredients under transboundary shipping models PLoS One 2018 13 e0194509 10.1371/journal.pone.0194509Open DOISearch in Google Scholar

3Deng J., Li X., Zheng D., Wang Y., Chen L., Song H., Wang T., Huang Y., Pang W., Tian K.: Establishment and application of an indirect ELISA for porcine circovirus 3. Arch Virol 2018, 163, 479–482. doi: 10.1007/s00705-017-3607-7. Deng J. Li X. Zheng D. Wang Y. Chen L. Song H. Wang T. Huang Y. Pang W. Tian K. Establishment and application of an indirect ELISA for porcine circovirus 3 Arch Virol 2018 163 479 482 10.1007/s00705-017-3607-7Open DOISearch in Google Scholar

4Faccini S., Barbieri I., Gilioli A., Sala G., Gibelli L.R., Moreno A., Sacchi C., Rosignoli C., Franzini G., Nigrelli A.: Detection and genetic characterization of Porcine circovirus type 3 in Italy. Transbound Emerg Dis 2017, 64, 1661–1664. doi: 10.1111/tbed.12714. Faccini S. Barbieri I. Gilioli A. Sala G. Gibelli L.R. Moreno A. Sacchi C. Rosignoli C. Franzini G. Nigrelli A. Detection and genetic characterization of Porcine circovirus type 3 in Italy Transbound Emerg Dis 2017 64 1661 1664 10.1111/tbed.12714Open DOISearch in Google Scholar

5Franzo G., Legnardi M., Tucciarone C.M., Drigo M., Klaumann F., Sohrmann M., Segalés J.: Porcine circovirus type 3: a threat to the pig industry? Vet Rec 2018, 182, 83. doi: 10.1136/vr.k91. Franzo G. Legnardi M. Tucciarone C.M. Drigo M. Klaumann F. Sohrmann M. Segalés J. Porcine circovirus type 3: a threat to the pig industry? Vet Rec 2018 182 83 10.1136/vr.k91Open DOISearch in Google Scholar

6Fux R., Söckler C., Link E.K., Renken C., Krejci R., Sutter G., Ritzmann M., Eddicks M.: Full genome characterization of porcine circovirus type 3 isolates reveals the existence of two distinct groups of virus strains. Virol J 2018, 15, 25. doi: 10.1186/s12985-018-0929-3. Fux R. Söckler C. Link E.K. Renken C. Krejci R. Sutter G. Ritzmann M. Eddicks M. Full genome characterization of porcine circovirus type 3 isolates reveals the existence of two distinct groups of virus strains Virol J 2018 15 25 10.1186/s12985-018-0929-3Open DOISearch in Google Scholar

7Ha Z., Xie C.Z., Li J.F., Wen S.B., Zhang K.L., Nan F.L., Zhang H., Guo Y.C., Wang W., Lu H.J., Jin N.Y.: Molecular detection and genomic characterization of porcine circovirus 3 in pigs from Northeast China. BMC Vet Res 2018, 14, 321. doi: 10.1186/s12917-018-1634-6. Ha Z. Xie C.Z. Li J.F. Wen S.B. Zhang K.L. Nan F.L. Zhang H. Guo Y.C. Wang W. Lu H.J. Jin N.Y. Molecular detection and genomic characterization of porcine circovirus 3 in pigs from Northeast China BMC Vet Res 2018 14 321 10.1186/s12917-018-1634-6Open DOISearch in Google Scholar

8Hayashi S., Ohshima Y., Furuya Y., Nagao A., Oroku K., Tsutsumi N., Sasakawa C., Sato T.: First detection of porcine circovirus type 3 in Japan. J Vet Med Sci 2018, 80, 1468–1472. doi: 10.1292/jvms.18-0079. Hayashi S. Ohshima Y. Furuya Y. Nagao A. Oroku K. Tsutsumi N. Sasakawa C. Sato T. First detection of porcine circovirus type 3 in Japan J Vet Med Sci 2018 80 1468 1472 10.1292/jvms.18-0079Open DOISearch in Google Scholar

9Kedkovid R., Woonwong Y., Arunorat J., Sirisereewan C., Sangpratum N., Kesdangsakonwut S., Tummaruk P., Teankum K., Assavacheep P., Jittimanee S., Thanawongnuwech R.: Porcine circovirus type 3 (PCV3) shedding in sow colostrum. Vet Microbiol 2018, 220, 12–17. doi: 10.1016/j.vetmic.2018.04.032. Kedkovid R. Woonwong Y. Arunorat J. Sirisereewan C. Sangpratum N. Kesdangsakonwut S. Tummaruk P. Teankum K. Assavacheep P. Jittimanee S. Thanawongnuwech R. Porcine circovirus type 3 (PCV3) shedding in sow colostrum Vet Microbiol 2018 220 12 17 10.1016/j.vetmic.2018.04.032Open DOISearch in Google Scholar

10Kedkovid R., Woonwong Y., Arunorat J., Sirisereewan C., Sangpratum N., Lumyai M., Kesdangsakonwut S., Teankum K., Jittimanee S., Thanawongnuwech R.: Porcine circovirus type 3 (PCV3) infection in grower pigs from a Thai farm suffering from porcine respiratory disease complex (PRDC). Vet Microbiol 2018, 215, 71–76. doi: 10.1016/j.vetmic.2018.01.004. Kedkovid R. Woonwong Y. Arunorat J. Sirisereewan C. Sangpratum N. Lumyai M. Kesdangsakonwut S. Teankum K. Jittimanee S. Thanawongnuwech R. Porcine circovirus type 3 (PCV3) infection in grower pigs from a Thai farm suffering from porcine respiratory disease complex (PRDC) Vet Microbiol 2018 215 71 76 10.1016/j.vetmic.2018.01.004Open DOISearch in Google Scholar

11Kim S.C., Nazki S., Kwon S., Juhng J.H., Mun K.H., Jeon D.Y., Jeong C.G., Khatun A., Kang S.J., Kim W.I.: The prevalence and genetic characteristics of porcine circovirus type 2 and 3 in Korea. BMC Vet Res 2018, 14, 294. doi: 10.1186/s12917-018-1614-x. Kim S.C. Nazki S. Kwon S. Juhng J.H. Mun K.H. Jeon D.Y. Jeong C.G. Khatun A. Kang S.J. Kim W.I. The prevalence and genetic characteristics of porcine circovirus type 2 and 3 in Korea BMC Vet Res 2018 14 294 10.1186/s12917-018-1614-xOpen DOISearch in Google Scholar

12Kim S.H., Park J.Y., Jung J.Y., Kim H.Y., Park Y.R., Lee K.K., Lyoo Y.S., Yeo S.G., Park C.K.: Detection and genetic characterization of porcine circovirus 3 from aborted fetuses and pigs with respiratory disease in Korea. J Vet Sci 2018, 19, 721–724. doi: 10.4142/jvs.2018.19.5.721. Kim S.H. Park J.Y. Jung J.Y. Kim H.Y. Park Y.R. Lee K.K. Lyoo Y.S. Yeo S.G. Park C.K. Detection and genetic characterization of porcine circovirus 3 from aborted fetuses and pigs with respiratory disease in Korea J Vet Sci 2018 19 721 724 10.4142/jvs.2018.19.5.721Open DOISearch in Google Scholar

13Klaumann F., Correa-Fiz F., Franzo G., Sibila M., Núñez J.I., Segalés J.: Current knowledge on porcine circovirus 3 (PCV-3): A novel virus with a yet unknown impact on the swine industry. Front Vet Sci 2018, 5, 315. doi: 10.3389/fvets.2018.00315. Klaumann F. Correa-Fiz F. Franzo G. Sibila M. Núñez J.I. Segalés J. Current knowledge on porcine circovirus 3 (PCV-3): A novel virus with a yet unknown impact on the swine industry Front Vet Sci 2018 5 315 10.3389/fvets.2018.00315Open DOISearch in Google Scholar

14Klaumann F., Dias-Alves A., Cabezón O., Mentaberre G., Castillo-Contreras R., López-Béjar M., Casas-Díaz E., Sibila M., Correa-Fiz F., Segalés J.: Porcine circovirus 3 is highly prevalent in serum and tissues and may persistently infect wild boar Sus scrofa scrofa Transbound Emerg Dis 2019, 66, 91–101. doi: 10.1111/tbed.12988. Klaumann F. Dias-Alves A. Cabezón O. Mentaberre G. Castillo-Contreras R. López-Béjar M. Casas-Díaz E. Sibila M. Correa-Fiz F. Segalés J. Porcine circovirus 3 is highly prevalent in serum and tissues and may persistently infect wild boar Sus scrofa scrofa Transbound Emerg Dis 2019 66 91 101 10.1111/tbed.12988Open DOISearch in Google Scholar

15Klaumann F., Franzo G., Sohrmann M., Correa-Fiz F., Drigo M., Núñez J.I., Sibila M., Segalés J.: Retrospective detection of Porcine circovirus 3 (PCV-3) in pig serum samples from Spain. Transbound Emerg Dis 2018, 65, 1290–1296. doi: 10.1111/tbed.12876. Klaumann F. Franzo G. Sohrmann M. Correa-Fiz F. Drigo M. Núñez J.I. Sibila M. Segalés J. Retrospective detection of Porcine circovirus 3 (PCV-3) in pig serum samples from Spain Transbound Emerg Dis 2018 65 1290 1296 10.1111/tbed.12876Open DOISearch in Google Scholar

16Li G., He W., Zhu H., Bi Y., Wang R., Xing G., Zhang C., Zhou J., Yuen K.Y., Gao G.F., Su S.: Origin, genetic diversity, and evolutionary dynamics of novel porcine circovirus 3. Adv Sci (Weinh) 2018, 5, 1800275. doi: 10.1002/advs.201800275. Li G. He W. Zhu H. Bi Y. Wang R. Xing G. Zhang C. Zhou J. Yuen K.Y. Gao G.F. Su S. Origin, genetic diversity, and evolutionary dynamics of novel porcine circovirus 3 Adv Sci (Weinh) 2018 5 1800275 10.1002/advs.201800275Open DOISearch in Google Scholar

17Li G., Wang H., Wang S., Xing G., Zhang C., Zhang W., Liu J., Zhang J., Su S., Zhou J.: Insights into the genetic and host adaptability of emerging porcine circovirus 3. Virulence 2018, 9, 1301–1313. doi: 10.1080/21505594.2018.1492863. Li G. Wang H. Wang S. Xing G. Zhang C. Zhang W. Liu J. Zhang J. Su S. Zhou J. Insights into the genetic and host adaptability of emerging porcine circovirus 3 Virulence 2018 9 1301 1313 10.1080/21505594.2018.1492863Open DOISearch in Google Scholar

18Li X., Zhang C., Qiao M., Guo J., Xing G., Jin C., Wang J., Sun M., Tian K.: Molecular epidemiology of porcine circovirus type 3 infection in swine herds in China. Virol Sin 2018, 9. doi: 10.1007/s12250-018-0041-2. Li X. Zhang C. Qiao M. Guo J. Xing G. Jin C. Wang J. Sun M. Tian K. Molecular epidemiology of porcine circovirus type 3 infection in swine herds in China Virol Sin 2018 9 10.1007/s12250-018-0041-2Open DOISearch in Google Scholar

19Lu B., Qin Y., He Y., Liu L., Duan Q., Zhou Y., Li B., Chen Z., Liang J., Su Q., Bi B., Jiang D., Lu J., Zhao W.: Complete genome sequence of a novel porcine circovirus type 3 strain, CH/GX/1776D/2017, isolated from Guangxi, China. Genome Announc 2018, 6. pii: e00285–18. doi: 10.1128/genomeA. 00285-18. Lu B. Qin Y. He Y. Liu L. Duan Q. Zhou Y. Li B. Chen Z. Liang J. Su Q. Bi B. Jiang D. Lu J. Zhao W. Complete genome sequence of a novel porcine circovirus type 3 strain, CH/GX/1776D/2017, isolated from Guangxi, China Genome Announc 2018 6 pii e00285 18 10.1128/genomeA.00285-18Open DOISearch in Google Scholar

20Palinski R., Piñeyro P., Shang P., Yuan F., Guo R., Fang Y., Byers E., Hause B.M.: A novel porcine circovirus distantly related to known circoviruses is associated with porcine dermatitis and nephropathy syndrome and reproductive failure. J Virol 2016, 91. pii: e01879–16. doi: 10.1128/JVI.01879-16. Palinski R. Piñeyro P. Shang P. Yuan F. Guo R. Fang Y. Byers E. Hause B.M. A novel porcine circovirus distantly related to known circoviruses is associated with porcine dermatitis and nephropathy syndrome and reproductive failure J Virol 2016 91 pii e01879 16 10.1128/JVI.01879-16Open DOISearch in Google Scholar

21Phan T.G., Giannitti F., Rossow S., Marthaler D., Knutson T.P., Li L., Deng X., Resende T., Vannucci F., Delwart E.: Detection of a novel circovirus PCV3 in pigs with cardiac and multisystemic inflammation. Virol J 2016, 13, 184. doi: 10.1186/s12985-016-0642-z. Phan T.G. Giannitti F. Rossow S. Marthaler D. Knutson T.P. Li L. Deng X. Resende T. Vannucci F. Delwart E. Detection of a novel circovirus PCV3 in pigs with cardiac and multisystemic inflammation Virol J 2016 13 184 10.1186/s12985-016-0642-zOpen DOISearch in Google Scholar

22Saraiva G.L., Vidigal P.M.P., Fietto J.L.R., Bressan G.C., Silva Júnior A., de Almeida M.R.: Evolutionary analysis of porcine circovirus 3 (PCV3) indicates an ancient origin for its current strains and a worldwide dispersion. Virus Genes 2018, 54, 376–384. doi: 10.1007/s11262-018-1545-4. Saraiva G.L. Vidigal P.M.P. Fietto J.L.R. Bressan G.C. Silva Júnior A. de Almeida M.R. Evolutionary analysis of porcine circovirus 3 (PCV3) indicates an ancient origin for its current strains and a worldwide dispersion Virus Genes 2018 54 376 384 10.1007/s11262-018-1545-4Open DOISearch in Google Scholar

23Stadejek T., Woźniak A., Miłek D., Biernacka K.: First detection of porcine circovirus type 3 on commercial pig farms in Poland. Transbound Emerg Dis 2017, 64, 1350–1353. doi: 10.1111/tbed.12672. Stadejek T. Woźniak A. Miłek D. Biernacka K. First detection of porcine circovirus type 3 on commercial pig farms in Poland Transbound Emerg Dis 2017 64 1350 1353 10.1111/tbed.12672Open DOISearch in Google Scholar

24Sun J., Wei L., Lu Z., Mi S., Bao F., Guo H., Tu C., Zhu Y., Gong W.: Retrospective study of porcine circovirus 3 infection in China. Transbound Emerg Dis 2018, 65, 607–613. doi: 10.1111/tbed.12853. Sun J. Wei L. Lu Z. Mi S. Bao F. Guo H. Tu C. Zhu Y. Gong W. Retrospective study of porcine circovirus 3 infection in China Transbound Emerg Dis 2018 65 607 613 10.1111/tbed.12853Open DOISearch in Google Scholar

25Tochetto C., Lima D.A., Varela A.P.M., Loiko M.R., Paim W.P., Scheffer C.M., Herpich J.I., Cerva C., Schmitd C., Cibulski S.P., Santos A.C., Mayer F.Q., Roehe .P.M.: Full-genome sequence of porcine circovirus type 3 recovered from serum of sows with stillbirths in Brazil. Transbound Emerg Dis 2018, 65, 5–9. doi: 10.1111/tbed.12735. Tochetto C. Lima D.A. Varela A.P.M. Loiko M.R. Paim W.P. Scheffer C.M. Herpich J.I. Cerva C. Schmitd C. Cibulski S.P. Santos A.C. Mayer F.Q. Roehe P.M. Full-genome sequence of porcine circovirus type 3 recovered from serum of sows with stillbirths in Brazil Transbound Emerg Dis 2018 65 5 9 10.1111/tbed.12735Open DOISearch in Google Scholar

26Wen S., Sun W., Li Z., Zhuang X., Zhao G., Xie C., Zheng M., Jing J., Xiao P., Wang M., Han J., Ren J., Liu H., Lu H., Jin N.: The detection of porcine circovirus 3 in Guangxi, China. Transbound Emerg Dis 2018, 65, 27–31. doi: 10.1111/tbed.12754. Wen S. Sun W. Li Z. Zhuang X. Zhao G. Xie C. Zheng M. Jing J. Xiao P. Wang M. Han J. Ren J. Liu H. Lu H. Jin N. The detection of porcine circovirus 3 in Guangxi, China Transbound Emerg Dis 2018 65 27 31 10.1111/tbed.12754Open DOISearch in Google Scholar

27Xu P.L., Zhang Y., Zhao Y., Zheng H.H., Han H.Y., Zhang H.X., Chen H.Y., Yang M.F., Zheng L.L.: Detection and phylogenetic analysis of porcine circovirus type 3 in central China. Transbound Emerg Dis 2018, 65, 1163–1169. doi: 10.1111/tbed.12920. Xu P.L. Zhang Y. Zhao Y. Zheng H.H. Han H.Y. Zhang H.X. Chen H.Y. Yang M.F. Zheng L.L. Detection and phylogenetic analysis of porcine circovirus type 3 in central China Transbound Emerg Dis 2018 65 1163 1169 10.1111/tbed.12920Open DOISearch in Google Scholar

28Ye X., Berg M., Fossum C., Wallgren P., Blomström A.L.: Detection and genetic characterisation of porcine circovirus 3 from pigs in Sweden. Virus Genes 2018, 54, 466–469. doi: 10.1007/s11262-018-1553-4. Ye X. Berg M. Fossum C. Wallgren P. Blomström A.L. Detection and genetic characterisation of porcine circovirus 3 from pigs in Sweden Virus Genes 2018 54 466 469 10.1007/s11262-018-1553-4Open DOISearch in Google Scholar

29Yuzhakov A.G., Raev S.A., Alekseev K.P., Grebennikova T.V., Verkhovsky O.A., Zaberezhny A.D., Aliper T.I.: First detection and full genome sequence of porcine circovirus type 3 in Russia. Virus Genes 2018, 54, 608–611. doi: 10.1007/s11262-018-1582-z. Yuzhakov A.G. Raev S.A. Alekseev K.P. Grebennikova T.V. Verkhovsky O.A. Zaberezhny A.D. Aliper T.I. First detection and full genome sequence of porcine circovirus type 3 in Russia Virus Genes 2018 54 608 611 10.1007/s11262-018-1582-zOpen DOISearch in Google Scholar

30Zhai S.L., Chen S.N., Xu Z.H., Tang M.H., Wang F.G., Li X.J., Sun B.B., Deng S.F., Hu J., Lv D.H., Wen X.H., Yuan J., Luo M.L., Wei W.K.: Porcine circovirus type 2 in China: an update on and insights to its prevalence and control. Virol J 2014, 11, 88. doi: 10.1186/1743-422X-11-88. Zhai S.L. Chen S.N. Xu Z.H. Tang M.H. Wang F.G. Li X.J. Sun B.B. Deng S.F. Hu J. Lv D.H. Wen X.H. Yuan J. Luo M.L. Wei W.K. Porcine circovirus type 2 in China: an update on and insights to its prevalence and control Virol J 2014 11 88 10.1186/1743-422X-11-88Open DOISearch in Google Scholar

31Zhai S.L., Zhou X., Zhang H., Hause B.M., Lin T., Liu R., Chen Q.L., Wei W.K., Lv D.H., Wen X.H., Li F., Wang D.: Comparative epidemiology of porcine circovirus type 3 in pigs with different clinical presentations. Virol J 2017, 14, 222. doi: 10.1186/s12985-017-0892-4. Zhai S.L. Zhou X. Zhang H. Hause B.M. Lin T. Liu R. Chen Q.L. Wei W.K. Lv D.H. Wen X.H. Li F. Wang D. Comparative epidemiology of porcine circovirus type 3 in pigs with different clinical presentations Virol J 2017 14 222 10.1186/s12985-017-0892-4Open DOISearch in Google Scholar

32Zheng S., Shi J., Wu X., Peng Z., Xin C., Zhang L., Liu Y., Gao M., Xu S., Han H., Yu J., Sun W., Cong X., Li J., Wang J.: Presence of Torque teno sus virus 1 and 2 in porcine circovirus 3-positive pigs. Transbound Emerg Dis 2018, 65, 327–330. doi: 10.1111/tbed.12792. Zheng S. Shi J. Wu X. Peng Z. Xin C. Zhang L. Liu Y. Gao M. Xu S. Han H. Yu J. Sun W. Cong X. Li J. Wang J. Presence of Torque teno sus virus 1 and 2 in porcine circovirus 3-positive pigs Transbound Emerg Dis 2018 65 327 330 10.1111/tbed.12792Open DOISearch in Google Scholar

33Zou Y., Zhang N., Zhang J., Zhang S., Jiang Y., Wang D., Tan Q., Yang Y., Wang N.: Molecular detection and sequence analysis of porcine circovirus type 3 in sow sera from farms with prolonged histories of reproductive problems in Hunan, China. Arch Virol 2018, 163, 2841–2847. doi: 10.1007/s00705-018-3914-7. Zou Y. Zhang N. Zhang J. Zhang S. Jiang Y. Wang D. Tan Q. Yang Y. Wang N. Molecular detection and sequence analysis of porcine circovirus type 3 in sow sera from farms with prolonged histories of reproductive problems in Hunan, China Arch Virol 2018 163 2841 2847 10.1007/s00705-018-3914-7Open DOISearch in Google Scholar