<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Rapid development in the field of tissue engineering necessitates implementation of monitoring methods for evaluation of the viability and characteristics of the cell cultures in a real-time, non-invasive and non-destructive manner. Current monitoring techniques are mainly histological and require labeling and involve destructive tests to characterize cell cultures. Bioimpedance measurement technique which benefits from measurement of electrical properties of the biological tissues, offers a non-invasive, label-free and real-time solution for monitoring tissue engineered constructs. This review outlines the fundamentals of bioimpedance, as well as electrical properties of the biological tissues, different types of cell culture constructs and possible electrode configuration set ups for performing bioimpedance measurements on these cell cultures. In addition, various bioimpedance measurement techniques and their applications in the field of tissue engineering are discussed.</p></abstract>

Rapid development in the field of tissue engineering necessitates implementation of monitoring methods for evaluation of the viability and characteristics of the cell cultures in a real-time, non-invasive and non-destructive manner. Current monitoring techniques are mainly histological and require labeling and involve destructive tests to characterize cell cultures. Bioimpedance measurement technique which benefits from measurement of electrical properties of the biological tissues, offers a non-invasive, label-free and real-time solution for monitoring tissue engineered constructs. This review outlines the fundamentals of bioimpedance, as well as electrical properties of the biological tissues, different types of cell culture constructs and possible electrode configuration set ups for performing bioimpedance measurements on these cell cultures. In addition, various bioimpedance measurement techniques and their applications in the field of tissue engineering are discussed.

Applications of bioimpedance measurement techniques in tissue engineering

Journal of Electrical Bioimpedance

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Applications of bioimpedance measurement techniques in tissue engineering"}

Rapid development in the field of tissue engineering necessitates implementation of monitoring methods for evaluation of the viability and characteristics of...

Applications of bioimpedance measurement techniques in tissue engineering

Article Category: Review Article

Published Online: Dec 31, 2018

Page range: 142 - 158

Received: Dec 14, 2018

DOI: https://doi.org/10.2478/joeb-2018-0019

Keywords
Tissue Engineering, Bioimpedance Measurement, Non-invasive monitoring

© 2018 M. Amini, J. Hisdal, H. Kalvøy published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Applications of bioimpedance measurement techniques in tissue engineering

Article Category: Review Article

Published Online: Dec 31, 2018

Page range: 142 - 158

Received: Dec 14, 2018

DOI: https://doi.org/10.2478/joeb-2018-0019

KeywordsTissue Engineering, Bioimpedance Measurement, Non-invasive monitoring

© 2018 M. Amini, J. Hisdal, H. Kalvøy published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Tissue Engineering, Bioimpedance Measurement, Non-invasive monitoring