<abstract xmlns="http://www.w3.org/1999/xhtml"><p>It has been suggested that it is possible to monitor the menstrual cycle by measuring the concentration of urinary reproductive steroids. This neglects the variation in void volume and in urine production rate. In neither case has any systematic analysis been reported previously. Overnight urine samples were collected each day for one complete cycle by 24 women and the void volumes and intervoid times were recorded. The void volume and urine production rate were approximately lognormally distributed and the intervoid time was approximately normally distributed. Using these distributions we consider the implications of the variation in void volume and urine production rate for the comparison of the concentrations of a urinary analyte in two samples.</p></abstract>

It has been suggested that it is possible to monitor the menstrual cycle by measuring the concentration of urinary reproductive steroids. This neglects the variation in void volume and in urine production rate. In neither case has any systematic analysis been reported previously. Overnight urine samples were collected each day for one complete cycle by 24 women and the void volumes and intervoid times were recorded. The void volume and urine production rate were approximately lognormally distributed and the intervoid time was approximately normally distributed. Using these distributions we consider the implications of the variation in void volume and urine production rate for the comparison of the concentrations of a urinary analyte in two samples.

On the distribution of urine output in normally cycling women

Biometrical Letters

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"On the distribution of urine output in normally cycling women"}

It has been suggested that it is possible to monitor the menstrual cycle by measuring the concentration of urinary reproductive steroids. This neglects the...

On the distribution of urine output in normally cycling women

Published Online: Jun 13, 2019

Page range: 71 - 87

DOI: https://doi.org/10.2478/bile-2019-0006

Keywords
distribution, menstrual cycle, urine, urine production rate

© 2019 Delwyn G. Cooke et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

On the distribution of urine output in normally cycling women

Published Online: Jun 13, 2019

Page range: 71 - 87

DOI: https://doi.org/10.2478/bile-2019-0006

Keywordsdistribution, menstrual cycle, urine, urine production rate

© 2019 Delwyn G. Cooke et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
distribution, menstrual cycle, urine, urine production rate