Optimization of the extraction parameters of Aloe Vera polyphenols and study of antioxidant and antifungal activities: application to molds isolated from durum wheat

[1]. Djermoun, A., La production céréalière en Algérie : les principales caractéristiques, Revue Nature et Technologie,2009, 1, 45-53Search in Google Scholar

[2]. Scariot M. A.; Radünz,L.L.; Dionello, R.G.; Toni, J.R.; Mossi, A.J.; Reichert Júnior, F.W.,Quality of wheat grains harvested with different moisture contents and stored in hermetic and conventional system., Journal of Stored Products Research,2018, 75, 29-3410.1016/j.jspr.2017.11.005Search in Google Scholar

[3]. Kibar, H., Influence of storage conditions on the properties of wheat varieties, Journal of Stored Products Research,2015, 62, 8-1510.1016/j.jspr.2015.03.001Search in Google Scholar

[4]. Mohapatra, D.; Kumar, S.; Kotwaliwale, N.; Singh, K.K.,Critical factors responsible for fungi growth in stored food grains and non-Chemical approaches for their control, Industrial Crops & Products,2017, 108, 162–18210.1016/j.indcrop.2017.06.039Search in Google Scholar

[5]. Nithya, U.; Chelladurai, V.; Jayas, D. S.; White, N.D.G., Safe storage guidelines for duram wheat, Journal of Stored Products Research,2011, 47, 328–33.Search in Google Scholar

[6]. Tsehaye, H.; Brurberg, M.B.; Sundheim, L.; Assefa, D.; Tronsmo, A.; Tronsmo, A.M., Natural occurrence of Fusarium species and fumonisin on maize grains in Ethiopia, Eur. J. Plant Pathol.,2017, 147, 141–155.Search in Google Scholar

[7]. Fleurat-Lessard, F.,Integrated management of the risks of stored grain spoilage by seedborne fungi and contamination by storage mould mycotoxins – An update, Journal of Stored Products Research,2017, 71, 22-4010.1016/j.jspr.2016.10.002Search in Google Scholar

[8]. Matthews, S.; Noli, E.; Demir, I.; Khajeh-Hosseini, M.; Wagner, M.H., Evaluation of seed quality: from physiology to international standardization, Seed Sci. Res.,2012, 22, S69-S73.10.1017/S0960258511000365Search in Google Scholar

[9]. Villers, P., Food safety and aflatoxin control, J. Food Res,2017, 6, 38–49.10.5539/jfr.v6n2p38Search in Google Scholar

[10]. Kumar, N., Green leaf volatiles in management of storage fungi of chick pea (Cicer arietinum L.), Ann. Plant Prot. Sci.,2017, 25, 171–175.Search in Google Scholar

[11]. Del Palacio, A.; Bettucci, L.;Pan, D., Fusarium and Aspergillus mycotoxins contaminating wheat silage for dairy cattle feeding in Uruguay, Braz J Microbiol., 2016, 47(4), 1000-1005.10.1016/j.bjm.2016.06.004505233227522933Search in Google Scholar

[12]. Mohapatra, D.; Kumar, S.; Kotwaliwale, N.; Singh, K.K., Critical factors responsible for fungi growth in stored food grains and non-chemical approaches for their control, Ind. Crops and Prod.,2017, 108, 162-182.Search in Google Scholar

[13]. WHO.Rapport de la Conférence internationale sur la gestiondes produits chimiques sur les travaux de sa troisième session, 2012. http://www.who.int/ipcs/saicm/saicm/fr/Search in Google Scholar

[14]. Anžlovar, S.; Likar, M.; Dolenc Koce, J., Antifungal potential of thyme essential oil as a preservative for storage of wheat seeds, Acta Botan. Croa., 2017, 76, 64–71.10.1515/botcro-2016-0044Search in Google Scholar

[15]. Salehi, B.; Albayrak, S.; Antolak, H.; Kręgiel, D.; Pawlikowska, E.; Sharifi-Rad, M.; Uprety, Y.; Tsouh Fokou, P.V.; Yousef, Z.; Amiruddin Zakaria, Z.; Varoni, E.M.; Sharopov, F.; Martins, N.; Iriti, M.; Sharifi-Rad, J., AloeGenus Plants: From Farm to Food Applications and Phytopharmacotherapy, Int. J. Mol. Sci.,2018, 19, 284310.3390/ijms19092843616331530235891Search in Google Scholar

[16]. Salehi, B.; Valussi, M.; Jugran, A.K.; Martorell, M.; Ramírez-Alarcón, K.; Stojanović-Radić, Z.Z.; Antolak, H.; Kr˛egiel, D.; Mileski, K.S.; Sharifi-Rad, M.; et al., Nepeta species: From farm to food applications and phytotherapy, Trends Food Sci. Technol.,2018, 80, 104–122.10.1016/j.tifs.2018.07.030Search in Google Scholar

[17]. Lawless, J.; Allan, J., The clinical composition of Aloe Vera. In: Aloe Vera: Natural Wonder Cure. London: Thorsons Publishing Ltd, 2000, 161-171.Search in Google Scholar

[18]. Ferro,V.A.; Bradbury, F.; Cameron, P.; Shakir,E.; Rahman, S.R.; Stimson, W.H., In vitro susceptibilities of Shigella flexneri and Streptococcus pyogenes to inner gel of Aloe barbadensis Miller, Agents Chemother., 2003, 47, 1137-1139.10.1128/AAC.47.3.1137-1139.2003Search in Google Scholar

[19]. Radha, M.H.; Laxmipriya, N.P., Evaluation of biological properties and clinical effectiveness of Aloe Vera: A systematic review, Journal of Traditional and Complementary Medicine,2015,5, 21-2610.1016/j.jtcme.2014.10.006Search in Google Scholar

[20]. Abdolshahi, A.; Naybandi-Atashi, S.; Heydari-Majd, M.; Salehi, B.; Kobarfard, F.; Ayatollahi, S.A.; Ata, A.; Tabanelli, G.; Sharifi-Rad, M.; Montanari, C.; et al., Antibacterial activity of some Lamiaceae species against Staphylococcus aureus in yoghurt-based drink (Doogh), Cell. Mol. Biol. (Noisy-le-Grand, France),2018, 64, 71–7710.14715/cmb/2018.64.8.11Search in Google Scholar

[21]. Laib, I.; Barkat, M., Optimization of Conditions for Extraction of Polyphenols and the Determination of the Impact of Cooking on Total Polyphenolic, Antioxidant, and Anticholinesterase Activities of Potato, Foods,2018, 7, 36.10.3390/foods7030036Search in Google Scholar

[22]. Waterhouse, A.; Folin-Ciocalteu, Micro Method for Total Phenol in Wine, Food Anal. Chem.,1999, 299, 152-78Search in Google Scholar

[23]. Woisky, R.; Salatino, A., Analysis of propolis: some parameters and procedures for chemical quality control, J. Apic. Res,1998, 37, 99-10510.1080/00218839.1998.11100961Search in Google Scholar

[24]. Skerget, M.; Kotnik, P.; Hadolin, M.; Hras, A.R.; Simonic, M.; Knez, Z., Phenols, proanthocyanidins, flavones and flavonols in some plant materials and their antioxidant activities, Food Chem.,2005, 89, 191–19810.1016/j.foodchem.2004.02.025Search in Google Scholar

[25]. Blois, M.S., Antioxidant determinations by the use of a stable free radical, Nature,1958, 181, 1199–120010.1038/1811199a0Search in Google Scholar

[26]. Re, R.; Pellegrini, N.; Proteggente, A.; Pannala, A.; Yang, M.; Rice-Evans, C., Antioxidant activity applying an improved ABTS radical cation decolorization assay, Free Radic. Biol. Med.,1999, 26, 1231.10.1016/S0891-5849(98)00315-3Search in Google Scholar

[27]. Özyürek, M.; Güçlü, K.; Apak, R., The main andmodified CUPRAC methods of antioxidant measurement, TrAC-Trends Anal. Chem.,2011, 30, 652–664.10.1016/j.trac.2010.11.016Search in Google Scholar

[28]. Pitt,J.I.; HockingaD., Fungi and food spoilage. Springer, London & New York, 1999, 501.Search in Google Scholar

[29]. Gakuubi, M.M.; Maina, A.W.; Wagacha,J.M.,Antifungal Activity of Essential Oil of Eucalyptus camaldulensis Dehnh. against Selected Fusarium spp., International Journal of Microbiology,2017,2017, 7.10.1155/2017/8761610523998828127308Search in Google Scholar

[30]. Kordali, S.; Cakir, A.; Zengin, H.; Duru, M. E., Antifungical Activities of The leaves of three Pistacia species grown in Turkey, Fitoterapia, 2003, 74, 164-167.10.1016/S0367-326X(02)00320-9Search in Google Scholar

[31]. Nejatzadeh-Barandozi, F.,Antibacterial activities and antioxidant capacity of Aloe Vera., Organic and Medicinal Chemistry Letters,2013,. 3, 2191-2858.10.1186/2191-2858-3-5372954023870710Search in Google Scholar

[32]. Kumar, S.; Yadav, A.; Yadav, M.; Yadav, J.P.,Effect of climate change on phytochemical diversity, total phenolic content and in vitro antioxidant activity of Aloe Vera (L.), Burm.f. BioMed Central., 2017, 1010.1186/s13104-017-2385-3526434128118858Search in Google Scholar

[33]. Vastrad, J.V.; Goudar, G.; Byadgi S.A.; Devi, R.D.; Kotur, R., Identification of bio-active components in leaf extracts of Aloe Vera, Ocimum tenuiflorum(Tulasi) and Tinospora cordifolia (Amrutballi), J. Med. Plants Res., 2015, 9(28), 764-770.10.5897/JMPR2013.5197Search in Google Scholar

[34]. Suhaj, M.,Spice antioxidants isolation and their antiradical activity: à review, Journal of Food Composition and Analysis,2006, 19, 531–537.10.1016/j.jfca.2004.11.005Search in Google Scholar

[35]. Muthukumaran, P.; Divya, R.; Indhumathi, E.; Keerthika, C.,Total phenolic and flavonoid content of membrane processed Aloe Veraextract: a comparative study, International Food Research Journal,2018, 25(4), 1450-1456.Search in Google Scholar

[36]. Amoo, S.O.; Aremu, A.O.; Van Staden, J., In vitro plant regeneration, secondary metabolite production and antioxidant activity of micropropagated Aloe arborescens Mill., Plant Cell Tissue Organ Cult.,2012, 111, 345–35810.1007/s11240-012-0200-3Search in Google Scholar

[37]. López, A.; de Tangil, M.S.; Vega-Orellana, O.; Ramírez, A.S.; Rico, M., Phenolic Constituents, Antioxidant and Preliminary Antimycoplasmic Activities of Leaf Skin and Flowers of Aloe Vera (L.) Burm. f. (syn. A. barbadensis Mill.) from the Canary Islands (Spain), Molecules,2013, 18, 4942-4954.10.3390/molecules18054942627012923624648Search in Google Scholar

[38]. Bhalla, A.; Chauhan, U.K.,Identification of Antihyperlipidemic components in Aloe Verathrough reverse phase HPLC, Journal of Biological Sciences and Medicine,2015,1, 21-27Search in Google Scholar

[39]. Cock, I., The genus aloe: Phytochemistry and therapeutic uses including treatments for gastrointestinal conditions and chronic inflammation. In Novel Natural Products: Therapeutic Effects in Pain, Arthritis and Gastro-Intestinal Diseases; Springer: Berlin, Germany, 2015, 179–235.10.1007/978-3-0348-0927-6_626462368Search in Google Scholar

[40]. Keyhanian, S.; Stahl-Biskup, E., Phenolic constituents in dried flowers of Aloe Vera (Aloe barbadensis) and their in vitro antioxidative capacity, Planta Med.,2007, 73, 599–602.10.1055/s-2007-96720217520524Search in Google Scholar

[41]. Okamura, N.; Asai, M.; Hine, N.; Yagi, A., High-performance liquid chromatographic determination of phenolic compounds in Aloe species, J. Chromatogr. A,1996, 746, 225–231.Search in Google Scholar

[42]. Park, M.K.; Park, J.H.; Kim, N.Y.; Shin, Y.G.; Choi, Y.S.; Lee, J.G.; Kim, K.H.; Lee, S.K., Analysis of 13 phenolic compounds in Aloe species by high performance liquid chromatography, Phytochem. Anal.,1998, 9, 186–191.Search in Google Scholar

[43]. Haritha, K.; Ramesh, B.; Saralakumari, D., Effect of Aloe Vera gel on antioxidant enzymes in streptozotocin-induced cataractogenesis in male and female Wistar rats, J Acute Med.,2014, 4(1),38–4410.1016/j.jacme.2014.01.005Search in Google Scholar

[44]. Lee, H.; Guo, Y; Ohta, M.; Xiong, L.; Stevenson, B.; Zhu, J.K., LOS2, a genetic locus acquired for cold responsive gene transcription encodes a bifunctional enolase, EMBO J.,2002, 21, 2692–702.Search in Google Scholar

[45]. Hu, Y.; Xu, J.; Hu Q.,Evaluation of antioxidant potential of Aloe Vera(Aloe barbadensis Miller) extracts, J Agric Food Chem.,2003, 51(26), 7788.10.1021/jf034255i14664546Search in Google Scholar

[46]. Saritha M.,Efficacy of topical Aloe Verain patients with oral lichen planus: à randomized double-blind study, J Oral Pathology and Medicine,2010, 39 (10), 735–740.10.1111/j.1600-0714.2010.00947.x20923446Search in Google Scholar

[47]. Salawu, K.M.; Ajaiyeoba, E.O.; Ogbole, O.O.; Adeniji, J.A; Faleye, T.C.; Agunu, A., Antioxidant, brine shrimp lethality and antiproliferative properties of gel and leaf extracts of Aloe schweinfurthii and Aloe Vera, J Herbs Spices Med Plants,2017, 23(4), 263-27.10.1080/10496475.2017.1318328Search in Google Scholar

[48]. Pfohl-Leszkowicz, A.,Métabolisation des mycotoxines-Effets biologiques et pathologies-Ecotoxicogenèse. Dans Les mycotoxines dans l’alimentation : évaluation et gestion du risque. De Conseil Supérieur d’Hygiène Publique de France. Technique et Documentation, Paris, 1999, 18-35Search in Google Scholar

[49]. Miller, J. D., Fungi and mycotoxins in grain: implications for stored product research, J. Stored Prod. Res,1995, 31, 1-1610.1016/0022-474X(94)00039-VSearch in Google Scholar

[50]. Filtenborg, O.; Frisvad, J.C.; Thrane, U., Moulds in food spoilage, International Journal of Food Microbiology,1996,33, 85–10210.1016/0168-1605(96)01153-1Search in Google Scholar

[51]. Magan, N.; Cayley, G.R; Lacey, J., Effect of water activity and temperature on mycotoxin production by Alternaria alternate in culture and on wheat grain, Applied and Environmental Microbiology,1984, 47, 1113-111710.1128/aem.47.5.1113-1117.1984Search in Google Scholar

[52]. Patriarca, A.; Azcarate, M. P.; Terminiello, L.; Fernandez Pinto, V., Mycotoxin production by Alternaria strains isolated from Argentinean wheat, Int. J. Food Microbiol.,2007, 119, 219–222.Search in Google Scholar

[53]. Castegnaro, M.; Pfohl-Leszkowicz, A., Les mycotoxines : contaminants omniprésents dans l’alimentation animale et humaine, dans La sécurité alimentaire du consommateur, Lavoisier, Tec&Doc, 2002.Search in Google Scholar

[54]. Botton,B.; Bertron, A.; Fevere, M.; Gauthier, S.; Guph, D.; Larpent, J.P.; Reymond, P.; Sanglier, J.J.; Vaysser, Y.; Veau, S.,Moisissures utiles et nuisibles importance industrielle. 2ème Edition Masson collection biotechnologies, 1990, 5-10Search in Google Scholar

[55]. Pitt, J.I.; Miscamble, B.F., Water relations of Aspergillus flavus and closely related species, Journal of Food Protection,1995, 58, 86-90.Search in Google Scholar

[56]. Joshaghani, H.; Namjoo, M.; Rostami, M.; Kohsar, F.; Niknejad, F., Mycoflora of fungal contaminationin wheat storage (silos) in Golestan Province, North of Iran. Jundishapur, Journal of Microbiology,2013, 6(4), e633410.5812/jjm.6334Search in Google Scholar

[57]. Ennouari, A.; Sanchis, V.; Rahouti, M.; Zinedine,A.,Isolation and molecular identification of mycotoxin producing fungi in durum wheat from Morocco, J. Mater. Environ. Sci.,2018, 9, 1470–1479Search in Google Scholar

[58]. Anžlovar, S.; Likar, M.; Koce, J.D., Antifungal potential of thyme essential oil as a preservative for storage of wheat seeds, Acta Bot. Croat.,2017, 76, 64-7110.1515/botcro-2016-0044Search in Google Scholar

[59]. Lorito, M.; Woo, S. L.; Garcia Fernandez, I.; Colucci, G.; Harman, G. E.; Pintor-Toro, J. A.; Filippone, E.; Muccifora, S.; Lawrence, C. B.; Zoina, A.; Tuzun, S.; Scala, F., Genes from mycoparasitic fungi as a source for improving plant resistance to fungal pathogens, Proc. Natl. Acad. Sci,. USA,1998, 95, 7860-7865.Search in Google Scholar

[60]. Saks, Y.; Barkai-Golan, R., Aloe Vera gel activity against plant pathogenic fungi, Postharvest Biol. Technol.,1995, 6, 159–16510.1016/0925-5214(94)00051-SSearch in Google Scholar

[61]. Pereira, A.P.; Ferreira, I.C.; Marcelino, F.; Valentão, P.; Andrade, P.B.; Seabra, R.; Estevinho, L.; Bento, A.; Pereira, J.A., Phenolic Compounds and Antimicrobial Activity of Olive (Olea europaea L. Cv. Cobrançosa) Leaves, Molecules,2007, 12, 1153-1162.Search in Google Scholar

[62]. Dammak, I.; Lasram, S.; Hamdi, Z.; Ben Moussa, O.; Mkadmini Hammi, K.; Trigui, I.; Houissa, H.; Mliki, A.; Hassouna, M., In vitro antifungal and anti-ochratoxigenic activities of Aloe vera gel against Aspergillus carbonarius isolated from grape, Industrial Crops & Products,2018, 123, 416–423.Search in Google Scholar

[63]. Harborne, J.B.; Williams, C.A., Advances in flavonoid research since 1992, Phytochemistry,2000, 55, 481–504.Search in Google Scholar

[64]. Singh, M.; Kaur, M.; Silakari, O., Flavones: An important scaffold for medicinal chemistry, Eur. J. Med. Chem., 2014, 84, 206–239.Search in Google Scholar

[65]. Nidiry, E.S.J.; Ganeshan G.; Lokesha, A.N.,Antifungal activity of some extractives and constituents of Aloe Vera.,Res. J. Med. Plant, 2011, 5, 196-200.Search in Google Scholar

[66]. Bhat, T.K.; Singh, B.; Sharma, O.P., Microbial degradation of tannins – a current perspective, Biodegradation,1998, 9, 343–35710.1023/A:1008397506963Search in Google Scholar

[67]. Castillejos, L.; Calsamiglia, S.; Ferret, A.,Effect of Essential Oil Active Compounds on Rumen Microbial Fermentation and Nutrient Flow in vitro systems, J Dairy Science,2006, 89, 2649-2658.Search in Google Scholar