<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Innate lymphoid cells (ILCs) represent the most recently identified members of the innate immune system. These cells play important roles in inflammation, tissue remodelling and metabolic disease. ILCs can be subdivided into three major groups according to their cytokine production. The role of ILCs in tumourigenesis and tumour progression is not completely clarified. In this review, we discuss whether and how ILCs are involved in tumour genesis, growth and metastasis.</p></abstract>

Innate lymphoid cells (ILCs) represent the most recently identified members of the innate immune system. These cells play important roles in inflammation, tissue remodelling and metabolic disease. ILCs can be subdivided into three major groups according to their cytokine production. The role of ILCs in tumourigenesis and tumour progression is not completely clarified. In this review, we discuss whether and how ILCs are involved in tumour genesis, growth and metastasis.

Innate Lymphoid Cells: Roles In Tumour Genesis And Progression

Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Serbia

Experimental and Applied Biomedical Research (EABR)

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

UROĐENE LIMFOIDNE ĆELIJE-ULOGA U GENEZI I RASTU TUMORA

Innate lymphoid cells (ILCs) represent the most recently identified members of the innate immune system. These cells play important roles in inflammation,...

Innate Lymphoid Cells: Roles In Tumour Genesis And Progression

Published Online: Jun 27, 2015

Page range: 85 - 91

Received: Mar 05, 2015

Accepted: May 13, 2015

DOI: https://doi.org/10.1515/sjecr-2015-0011

Keywords
Innate lymphoid cells, tumour, progression, antitumor immunity

© Ivan Jovanovic et al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Innate Lymphoid Cells: Roles In Tumour Genesis And Progression

Published Online: Jun 27, 2015

Page range: 85 - 91

Received: Mar 05, 2015

Accepted: May 13, 2015

DOI: https://doi.org/10.1515/sjecr-2015-0011

KeywordsInnate lymphoid cells, tumour, progression, antitumor immunity

© Ivan Jovanovic et al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Innate lymphoid cells, tumour, progression, antitumor immunity