[1. TADDEI S, CARACCIO N, VIRDIS A, DARDANO A, VERSARI D, GHIADONI L, et al. Impaired endothelium-dependent vasodilatation in subclinical hypothyroidism: beneficial effect of levothyroxine therapy. J Clin Endocrinol Metab. 2003; 88: 3731-3737.10.1210/jc.2003-03003912915662]Search in Google Scholar
[2. CANARIS GJ, MANOWITZ NR, MAYOR G, RIDGWAY EC. The Colorado thyroid disease prevalence study. Arch Intern Med. 2000; 160:526-34.10.1001/archinte.160.4.52610695693]Search in Google Scholar
[3. UPADYA UB, SUMA MN, SRINATH KM, PRASHANT A, DODDAMANI P, SHILPA SV, et al. Effect of insulin resistance in assessing the clinical outcome of clinical and subclinical hypothyroid patients. Journal of clinical and diagnostic research: JCDR. 2015; 9(2): OC01-. OC04.]Search in Google Scholar
[4. MAZAHERI T, SHARIFI F, KAMALI K. Insulin resistance in hypothyroid patients under Levothyroxine therapy: a comparison between those with and without thyroid autoimmunity. Journal of Diabetes & Metabolic Disorders. 2014; 13(1): 103.10.1186/s40200-014-0103-4421665625364704]Search in Google Scholar
[5. PEPPA M, KOLIAKI C, NIKOLOPOULOS P, RAPTIS SA. Skeletal muscle insulin resistance in endocrine disease. Journal of Biomedicine and Biotechnology 2010. Article ID 527850.10.1155/2010/527850284041320300436]Search in Google Scholar
[6. SINGH BM, GOSWAMI B, MALLIKA V. Association between insulin resistance and hypothyroidism in females attending a tertiary care hospital. Indian Journal of Clinical Biochemistry. 2010; 25 (2): 141-145.10.1007/s12291-010-0026-x345309723105900]Open DOISearch in Google Scholar
[7. CHUBB SA, DAVIS WA, DAVIS TM. Interactions among thyroid function, insulin sensitivity, and serum lipid concentrations: the Fremantle diabetes study. J Clin Endocrinol Metab. 2005; 90: 5317-20.10.1210/jc.2005-029815985488]Open DOISearch in Google Scholar
[8. LADENSON PW, SINGER PA, AIN KB, BAGCHI N, BIGOS ST, LEVY EG, et al. American Thyroid Association guidelines for detection of thyroid dysfunction. Arch Intern Med. 2000; 160: 1573–1575.10.1001/archinte.160.11.157310847249]Search in Google Scholar
[9. ASVOLD BO, VATTEN LJ, NILSEN TI, BJORO T. The association between TSH within the reference range and serum lipid concentrations in a population-based study. The HUNT Study. Eur J Endocrinol. 2007; 156: 181-6.]Search in Google Scholar
[10. PEARCE EN, WILSON PW, YANGY Q, VASAN RS, BRAVERMAN LE. Thyroid function and lipid subparticle sizes in patients with short term hypothyroidism and a population-based cohort. J Clin Endocrinol Metab. 2008; 93: 888-94.10.1210/jc.2007-1987226694618073305]Search in Google Scholar
[11. ÇATLI G, ANIK A, ÜNVER TUHAN H, BOBER E, ABACT A. The effect of L-thyroxine treatment on hypothyroid symptom scores and lipid profile in children with subclinical hypothyroidism. J Clin Res Pediatr Endocrinol. 2014; 6: 238-244.10.4274/jcrpe.1594429365925541895]Search in Google Scholar
[12. MUTLU S, PARLAK A, AYDOGAN U, AYDOGDU A, SOYKUT B, AKAY C, et al. The effect of levothyroxine replacement therapy on lipid profile and oxidative stress parameters in patients with subclinical hypothyroid. Archives of pharmacal research. 2013; 1-9.10.1007/s12272-013-0227-y23925559]Search in Google Scholar
[13. BAMASHMOOS SA, AL-NUZAILY MAK, AL-MEERI AM, ALI FHH. Relationship between total homocysteine, total cholesterol and creatinine levels in overt hypothyroid patients. SpringerPlus. 2013; 2: 423.10.1186/2193-1801-2-423376650724024107]Search in Google Scholar
[14. DAGRE AG, LEKAKIS JP, PAPAIOANNOU TG, PAPAMICHAEL CM, KOUTRAS DA, STAMATELOPOULOS SF, et al. Arterial stiffness is increased in subjects with hypothyroidism. Int J Cardiol. 2005; 103: 1-6.10.1016/j.ijcard.2004.05.06816061115]Search in Google Scholar
[15. OBRADOVIC M, GLUVIC Z, SUDAR-MILOVANOVIC E, PANIC A, TREBALJEVAC J, BAJIC V, et al. Nitric oxide as a marker for levo-thyroxine therapy in subclinical hypothyroid patients. Curr Vasc Pharmacol. 2016; 14(3): 266-70.10.2174/157016111466616020814353726853795]Open DOISearch in Google Scholar
[16. DAGRE AG, LEKAKIS JP, PROTOGRON AD. Abnormal endothelial function in female patients with hypothyroidism and borderline thyroid function. Int J Cardiol. 2007; 114: 332–338.10.1016/j.ijcard.2005.12.01316793150]Search in Google Scholar
[17. QUESADA A, SAINZ J, WANGSTEEN R, RODRIGUEZ-GOMEZ I, VARGAS F, OSUNA A. Nitric oxide synthase activity in hyperthyroid and hypothyroid rats. European Journal of Endocrinology. 2002; 147(1): 117-122.10.1530/eje.0.147011712088928]Search in Google Scholar
[18. 18. BRADLEY SE, STEPHAN F, COELHO JB, REVILLE P. The thyroid and the kidney. Kidney international. 1974; 6(5): 346-365.10.1038/ki.1974.1194431166]Open DOISearch in Google Scholar
[19. KLEIN I, OJAMAA K. Thyroid hormone and the cardiovascular system. New England Journal of Medicine. 2001; 344(7): 501-509.10.1056/NEJM20010215344070711172193]Search in Google Scholar
[20. DANZI S, KLEIN I. Thyroid hormone and blood pressure regulation. Curr Hypertens Rep. 2003; 5:513-20.10.1007/s11906-003-0060-714594573]Open DOISearch in Google Scholar
[21. BASKIN HJ, COBIN RH, DUICK DS, GHARIB H, GUTTLER RB, KAPLAN MM, et al. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hyperthyroidism and hypothyroidism. Endocr Pract. 2002; 8:457-469.10.4158/1934-2403-8.6.45727762623]Search in Google Scholar
[22. RAMSEY MW, GOODFELLOW J, JONES CJH, LUDDINTON LA, LEWIS MJ, HENDERSON AH. Endothelial control of arterial distensibility is impaired in chronic heart failure. Circulation. 1995; 92: 3212-3219.10.1161/01.CIR.92.11.32127586306]Open DOISearch in Google Scholar
[23. HUSSEIN WI, GREEN R, JACOBSEN DW, FAMAN C. Normalization of hyperhomocysteinemia with L-thyroxine in hypothyroidism. Annals of internal medicine. 1999; 131(5): 348-351.10.7326/0003-4819-131-5-199909070-0000510475887]Search in Google Scholar
[24. FICHTLSCHERER S, ROSENBERGER G, WALTER DH, BREUER S, DIMMELER S, ZEIHER AM. Elevated C-reactive protein levels and impaired endothelial vasoreactivity in patients with coronary artery disease. Circulation. 2000; 102: 1000-1006.10.1161/01.CIR.102.9.1000]Open DOISearch in Google Scholar
[25. SELLITTI DF, DENISSON D, AKAMIZU T, DOI SQ, KOHN LD, KOSHIYAMA H. Thyrotropin regulation of cyclic adenosine monophosphate production in human coronary artery smooth muscle cells. Thyroid. 2000; 10: 219-225.10.1089/thy.2000.10.21910779136]Search in Google Scholar
[26. PAPAIOANNOU GI, LAGASSE M, MATHER JF, THOMPSON PD. Treating hypothyroidism improves endothelial function. Metabolism. 2004; 53: 278-9.10.1016/j.metabol.2003.10.00315015136]Search in Google Scholar
[27. CAPPOLA AR, LADENSON PW. Hypothyroidism and atherosclerosis. The Journal of Clinical Endocrinology & Metabolism. 2003; 88(6): 2438-2444.10.1210/jc.2003-03039812788839]Open DOISearch in Google Scholar
[28. NESS GC, CHAMBERS CM. Feedback and hormonal regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase: the concept of cholesterol buffering capacity, Proc. Soc. Exp. Biol. Med. 2000; 224: 8-19.]Search in Google Scholar
[29. SHIN DJ, OSBORNE TF. Thyroid hormone regulation and cholesterol metabolism are connected through Sterol Regulatory Element Binding Protein-2 (SREBP-2). J Biol Chem. 2003; 278: 34114-8.10.1074/jbc.M30541720012829694]Search in Google Scholar
[30. HUUSKONEN J, VISHNU M, PULLINGER CR, FIELDING PE, FIELDING CJ. Regulation of ATP-binding cassette transporter A1 transcription by thyroid hormone receptor. Biochem. 2004; 43(6): 1626-1632.10.1021/bi030164314769039]Search in Google Scholar
[31. GOLDSTEIN JL, DEBOSE-BOYD RA, BROWN MS. Protein sensors for membrane sterols. Cell. 2006; 124(1): 35-46.10.1016/j.cell.2005.12.02216413480]Search in Google Scholar
[32. HASHIMOTO K, COHEN RN, YAMADA M, MARKAN KR, MONDEN T, SATOH T, et al. Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model. Journal of Biological Chemistry. 2006; 281(1): 295-302.10.1074/jbc.M50787720016260782]Search in Google Scholar
[33. LOPEZ D, ABISAMBRA SOCARRAS JF, BEDI M, NESS GC. Activation of the hepatic LDL receptor 703 promoter by thyroid hormone. Biochim Biophys Acta. 2007; 1771: 1216-1225.10.1016/j.bbalip.2007.05.00117572141]Search in Google Scholar
[34. JIN T, TENG X. Update on Lipid Metabolism and Thyroid Disorders. J Endocrinol Diabetes Obes. 2014; 2(3): 1043.]Search in Google Scholar
[35. BANSAL SK, YADAV R. A Study of the Extended Lipid Profile including Oxidized LDL, Small Dense LDL, Lipoprotein (a) and Apolipoproteins in the Assessment of Cardiovascular Risk in Hypothyroid Patients. Journal of clinical and diagnostic research: JCDR. 2016; 10(6): BC04.10.7860/JCDR/2016/19775.8067496363627504276]Search in Google Scholar
[36. JUNG CH, SUNG KC, SHIN HS, RHEE EJ, LEE WY, KIM BS, et al. Thyroid dysfunction and their relation to cardiovascular risk factors such as lipid profile, hsCRP, and waist hip ratio in Korea. Korean J Intern Med. 2003; 18: 146-53.10.3904/kjim.2003.18.3.146453163014619383]Open DOISearch in Google Scholar
[37. DUMAN D, SAHIN S, ESERTAS K, DEMIRTUNC R. Simvastatin improves endothelial function in patents with subclinical hypothyroidism. Heart Vessels. 2007; 22: 88-93.10.1007/s00380-006-0950-017390202]Open DOISearch in Google Scholar
[38. RIZOS C, ELISAF MS, LIBEROPOULOS EN. Effects of thyroid dysfunction on lipid profile. Open Cardiovascular Medicine Journal. 2011; 5: 76-84.10.2174/1874192401105010076310952721660244]Search in Google Scholar
[39. AL-TONSI AA, ABDEL-GAYOUM AA, SAAD M. The secondary dyslipidemia and deranged serum phosphate concentration in thyroid disorders. Exp Mol Pathol. 2004; 76: 182-7.10.1016/j.yexmp.2003.10.00615010297]Search in Google Scholar
[40. TEIXEIRA Pde F, REUTERS VS, FERREIRA MM, ALMEIDA CP, REIS FAA, BUESCU A, et al. Lipid profile in different degrees of hypothyroidism and effects of levothyroxine replacement in mild thyroid failure. Transl Res. 2008; 151: 224-31.10.1016/j.trsl.2007.12.00618355770]Search in Google Scholar
[41. MARWAHA R, TANDON N, GARG M, KANWAR R, SASTRY A, NARANG A, et al. Dyslipidemia in subclinical hypothyroidism in an Indian population. Clin Biochem. 2011; 44(14-15): 1214-1217.10.1016/j.clinbiochem.2011.07.00321782807]Open DOISearch in Google Scholar
[42. BOELAERT K, FRANKLYN J. Thyroid hormone in health and disease. Journal of Endocrinology. 2005; 187(1): 1-15.10.1677/joe.1.0613116214936]Search in Google Scholar
[43. RIFAI N, WARNICK GR. Lipids, lipoproteins, apolipoproteins, and other cardiovascular risk factors. In: Burtis CA, Ashwood ER, Bruns DE, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 4th ed. Philadelphia, Pa: Elsevier Saunders; 2006: 903–982.]Search in Google Scholar
[44. MARATOU E, HADJIDAKIS DJ, KOLLIAS A, TSEGKA K, PEPPA M, ALEVIZAKI M, et al. Studies of insulin resistance in patients with clinical and subclinical hypothyroidism. Eur J Endocrinol. 2009; 160: 785-90.10.1530/EJE-08-079719141606]Search in Google Scholar