Screen-detected ductal carcinoma in situ found on stereotactic vacuum-assisted biopsy of suspicious microcalcifications without mass: radiological-histological correlation
, , , and | Apr 23, 2016
About this article
Article Category: Research Article
Published Online: Apr 23, 2016
Page range: 145 - 152
Received: Nov 30, 2015
Accepted: Jan 26, 2016
DOI: https://doi.org/10.1515/raon-2016-0020
© 2016 Radiol Oncol
This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Statistical significance of dependency (chi-square test, P value)
| Patient age | Microcalcifications type | Microcalcifications distribution | Nuclear grade | Comedonecrosis | |
|---|---|---|---|---|---|
| Patient age | — | 0.5977 | 0.1936 | 0.9098 | 1 |
| Microcalcifications type | 0.5977 | — | 0.7278 | ||
| Microcalcifications distribution | 0.1936 | — | 0.0733 | ||
| Nuclear grade | 0.9098 | — | |||
| Comedonecrosis | 1 | 0.7278 | 0.0733 | — |
Association between microcalcifications distribution and type
| Microcalcifications distribution, n (%) | ||||
|---|---|---|---|---|
| Clustered | Grouped | Regional | ||
| Microcalcifications type, n [%] | ||||
| Powdery | 16 (19) [84] | 3 (10) [16] | 0 (-) [-] | [100%] |
| Crushed stone-like | 61 (72) [75] | 16 (51) [20] | 4 (36) [5] | [100%] |
| Casting type | 8 (9) [30] | 12 (39) [44] | 7 (64) [26] | [100%] |
| (100%) | (100%) | (100%) | ||
Association between comedonecrosis and microcalcifications
| Comedonecrosis, n (%) | |||
|---|---|---|---|
| Absent | Present | ||
| Microcalcifications Type, n [%] | |||
| Powdery | 10 (17) [53] | 9 (13) [47] | [100%] |
| Crushed stone-like | 35 (60) [43] | 46 (67) [57] | [100%] |
| Casting type | 13 (23) [48] | 14 (20) [52] | [100%] |
| (100%) | (100%) | P > 0.5 | |
| Distribution, n [%] | |||
| Clustered | 44 (76) [52] | 41 (59) [48] | [100%] |
| Grouped | 12 (21) [39] | 19 (28) [61] | [100%] |
| Regional | 2 (3) [18] | 9 (13) [82] | [100%] |
Association between nuclear grade and microcalcifications
| Microcalcifications Type, n [%] | ||||
|---|---|---|---|---|
| I (Low) | Nuclear grade, n (%) II (Intermediate) | III (High) | ||
| Powdery | 14 (20) [74] | 3 (8) [16] | 2 (11) [10] | [100%] |
| Crushed stone-like | 47 (66) [58] | 27 (71) [33] | 7 (39) [9] | [100%] |
| Casting type | 10 (14) [37] | 8 (21) [30] | 9 (50) [33] | [100%] |
| (100%) | (100%) | (100%) | ||
| Distribution, n [%] | ||||
| Clustered | 54 (76) [64] | 23 (60) [27] | 8 (44) [9] | [100%] |
| Grouped | 14 (20) [45] | 12 (32) [39] | 5 (28) [16] | [100%] |
| Regional | 3 (4) [27] | 3 (8) [27] | 5 (28) [46] | [100%] |
| (100%) | (100%) | (100%) | ||
Baseline characteristics
| n(%) | |
|---|---|
| Patient age | |
| 50–60 | 67 (53) |
| 61–69 | 60 (47) |
| Microcalcifications type | |
| Powdery | 19 (15) |
| Crushed stone-like | 81 (64) |
| Casting-type | 27 (21) |
| Microcalcifications distribution | |
| Clustered | 85 (67) |
| Grouped | 31 (24) |
| Regional | 11 (9) |
| Nuclear grade (NG) | |
| NG 1 (Low) | 71 (56) |
| NG 2 (Intermediate) | 38 (30) |
| NG 3 (High) | 18 (14) |
| Comedonecrosis | |
| Absent | 58 (46) |
| Present | 69 (54) |
Association between nuclear grade and comedonecrosis
| Nuclear grade, n (%) | ||||
|---|---|---|---|---|
| I (Low) | II (Intermediate) | III (High) | ||
| Comedonecrosis, n [%] | ||||
| Absent | 37 (52) [64] | 20 (53) [34] | 1 (6) [2] | [100%] |
| Present | 34 (48) [49] | 18 (47) [26] | 17 (94) [25] | [100%] |
| (100%) | (100%) | (100%) | ||