<abstract xmlns="http://www.w3.org/1999/xhtml">The present study investigates the synthesis and characterization of iron oxide nanoparticles (Fe3O4-NPs) for their antibacterial potential against <italic>Bacillus cereus</italic> and <italic>Klebsiella pneumonia</italic> by modified disc diffusion and broth agar dilution methods. DLS and XRD results revealed the average size of synthesized Fe3O4-NPs as 24 nm while XPS measurement exhibited the spin-orbit peak of Fe 2p3/2 binding energy at 511 eV. Fe3O4-NPs inhibited the growth of <italic>K. pneumoniae</italic> and <italic>B. cereus</italic> in both liquid and soild agar media, and displayed 26 mm and 22 mm zone of inhibitions, respectively. MIC of Fe3O4-NPs was found to be 5 μg/mL against these strains. However, MBC for these strains was observed at 40 μg/mL concentration of Fe3O4-NPs for exhibiting 40–50% loss in viable bacterial cells and 80 μg/mL concentration of Fe3O4-NPs acted as bactericidal for causing 90–99% loss in viability. Hence, these nanoparticles can be explored for their additional antimicrobial and biomedical applications.</abstract>

The present study investigates the synthesis and characterization of iron oxide nanoparticles (Fe3O4-NPs) for their antibacterial potential against Bacillus cereus and Klebsiella pneumonia by modified disc diffusion and broth agar dilution methods. DLS and XRD results revealed the average size of synthesized Fe3O4-NPs as 24 nm while XPS measurement exhibited the spin-orbit peak of Fe 2p3/2 binding energy at 511 eV. Fe3O4-NPs inhibited the growth of K. pneumoniae and B. cereus in both liquid and soild agar media, and displayed 26 mm and 22 mm zone of inhibitions, respectively. MIC of Fe3O4-NPs was found to be 5 μg/mL against these strains. However, MBC for these strains was observed at 40 μg/mL concentration of Fe3O4-NPs for exhibiting 40–50% loss in viable bacterial cells and 80 μg/mL concentration of Fe3O4-NPs acted as bactericidal for causing 90–99% loss in viability. Hence, these nanoparticles can be explored for their additional antimicrobial and biomedical applications.

Antibacterial activity of iron oxide nanoparticles synthesized by co-precipitation technology against <italic>Bacillus cereus</italic> and <italic>Klebsiella pneumoniae</italic>

Center of Excellence in Genomic Medicine Research

Center of Excellence in Environmental Studies

Ibn Sina National College for Medical Sciences, Department of Biochemistry

Center of Excellence for Advanced Materials Research

Ibn Sina National College for Medical Sciences, Physics Division, Basic Science Department

Polish Journal of Chemical Technology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Antibacterial activity of iron oxide nanoparticles synthesized by co-precipitation technology against  and 

The present study investigates the synthesis and characterization of iron oxide nanoparticles (Fe3O4-NPs) for their antibacterial potential against Bacillus...

Antibacterial activity of iron oxide nanoparticles synthesized by co-precipitation technology against Bacillus cereus and Klebsiella pneumoniae

Published Online: Dec 29, 2017

Page range: 110 - 115

DOI: https://doi.org/10.1515/pjct-2017-0076

Keywords
antibacterial activity, co-precipitation, iron oxide nanoparticles, Klebsiella pneumoniae, physico-chemical characterization

© 2017 Shakeel Ahmed Ansari et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Antibacterial activity of iron oxide nanoparticles synthesized by co-precipitation technology against Bacillus cereus and Klebsiella pneumoniae

Published Online: Dec 29, 2017

Page range: 110 - 115

DOI: https://doi.org/10.1515/pjct-2017-0076

Keywordsantibacterial activity, co-precipitation, iron oxide nanoparticles, Klebsiella pneumoniae, physico-chemical characterization

© 2017 Shakeel Ahmed Ansari et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
antibacterial activity, co-precipitation, iron oxide nanoparticles, Klebsiella pneumoniae, physico-chemical characterization