<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Stem cells are characterized by their ability to self-renew and differentiate into various cell types. They offer great potential for a wide range of applications, however, medical studies on the use of embryonal stem cells are largely limited to bioethical issues searching for alternative sources of stem cells, which include isolating cells from adult organisms or inducing pluripotentiality of somatic cells by administration of transcription factors. Nowadays, stem cells are used to study the mechanisms of cell differentiation and treat diseases that are commonly considered to be incurable, such as diabetes and neurodegenerative diseases, as well as enable regeneration of skin damage and myocardium. This review introduces the subject of stem cells, their sources and application in regenerative medicine.</p></abstract>

Stem cells are characterized by their ability to self-renew and differentiate into various cell types. They offer great potential for a wide range of applications, however, medical studies on the use of embryonal stem cells are largely limited to bioethical issues searching for alternative sources of stem cells, which include isolating cells from adult organisms or inducing pluripotentiality of somatic cells by administration of transcription factors. Nowadays, stem cells are used to study the mechanisms of cell differentiation and treat diseases that are commonly considered to be incurable, such as diabetes and neurodegenerative diseases, as well as enable regeneration of skin damage and myocardium. This review introduces the subject of stem cells, their sources and application in regenerative medicine.

The possibilities of stem cell application in regenerative medicine

Institute of Histology and Embryology Medical Department of the University of Rzeszów, Poland

Histology and Embryology Department with the Experimental Cytology Laboratory of the Medical University of Lublin, Poland

Polish Hyperbaric Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"The possibilities of stem cell application in regenerative medicine"}

Stem cells are characterized by their ability to self-renew and differentiate into various cell types. They offer great potential for a wide range of...

The possibilities of stem cell application in regenerative medicine

Published Online: May 20, 2016

Page range: 49 - 64

Received: Nov 19, 2015

Accepted: Jan 12, 2016

DOI: https://doi.org/10.1515/phr-2016-0007

Keywords
stem cells, induced pluripotent cells, cell therapies, diabetes, neurodegenerative diseases

© 2016 Sabina Galiniak et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The possibilities of stem cell application in regenerative medicine

Published Online: May 20, 2016

Page range: 49 - 64

Received: Nov 19, 2015

Accepted: Jan 12, 2016

DOI: https://doi.org/10.1515/phr-2016-0007

Keywordsstem cells, induced pluripotent cells, cell therapies, diabetes, neurodegenerative diseases

© 2016 Sabina Galiniak et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
stem cells, induced pluripotent cells, cell therapies, diabetes, neurodegenerative diseases