Enrofloxacin decreases IL-6 and TNF-α production by lipopolysaccharide-stimulated porcine peripheral blood mononuclear cells

1. Araujo F.G., Slifer T.L., Remington J.S.: Effect of moxifloxacin on secretion of cytokines by human monocytes stimulated with lipopolysaccharide. Clin Microbiol Infect 2002, 8, 26–30.10.1046/j.1469-0691.2002.00374.x11906497Search in Google Scholar

2. Bailly S., Fay M., Ferrua B., Gougerot-Pocidalo M.A.: Ciprofloxacin treatment in vivo increases the ex vivo capacity of lipopolysaccharide-stimulated human monocytes to produce IL-1, IL-6 and tumour necrosis factor-alpha. Clin Exp Immunol 1991, 85, 331–334.10.1111/j.1365-2249.1991.tb05728.x15357571864014Search in Google Scholar

3. Bazzoni F., Beutler B.: The tumor necrosis factor ligand and receptor families. New Engl J Med 1996, 334, 1717–1725.10.1056/NEJM1996062733426078637518Search in Google Scholar

4. Chirigos N.A., De Simone C.: Immunoregulatory biological response modifiers: effect of cytokines on septic shock. Mediators Inflam 1993, 2, 5–10.10.1155/S0962935193000675236544218475571Search in Google Scholar

5. Choi I.S., Collisson E.W., Maheswaran S.K., Yoo H.S.: Evaluation of cytokine gene expression in porcine spleen cells, peripheral blood mononuclear cells, and alveolar macrophages by competitive RT-PCR. FEMS Immunol Med Microbiol 2002, 34, 119–126.10.1111/j.1574-695X.2002.tb00612.x12381462Search in Google Scholar

6. Dalhoff A.: Immunomodulatory activities of fluoroquinolones. Infection 2005, 33, 255–270.10.1007/s15010-005-8209-816518713Search in Google Scholar

7. Gattoni A., Parlato A., Vangieri B., Bresciani M., Derna R.: Interferon-gamma: biologic functions and HCV therapy (type I/II). Clin Therap 2006, 157, 377–386.Search in Google Scholar

8. Khalifeh M.S., Amawi M.M., Abu-Basha E.A., Bani Yonis I.: Assessment of humoral and cellular-mediated immune response in chickens treated with tilmicosin, florfenicol or enrofloxacin at the time of Newcastle disease vaccination. Poultry Sci 2009, 88, 2118–2124.10.3382/ps.2009-0021519762865Search in Google Scholar

9. Khan A.A., Slifer T.R., Remington J.S.: Effect of trovafloxacin on production of cytokines by human monocytes. Antimicrob Agent Chemother 1998, 42, 1713–1717.10.1128/AAC.42.7.17131056719661009Search in Google Scholar

10. Koma-Komai M., Gilchrist D.S., Xu D.: Direct recognition of LPS by human but not murine CD8+ T cells via TLR4 complex. Eur J Immunol 2009, 39, 1564–1572.10.1002/eji.20083886619405031Search in Google Scholar

11. Lauder S.N., Jones E., Smart K., Bloom A., Williams A.S., Hindle J.P., Ondondo B., Taylor P.R., Clement M., Fielding C., Godkin A.J., Jones S.A., Gallimore A.M.: Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology. Eur J Immunol 2013, 43, 2613–2625.10.1002/eji.201243018388638623857287Search in Google Scholar

12. Marsh C.B., Wewers M.D.: The pathogenesis of sepsis. Factors that modulate the response to gram-negative bacterial infection. Clin Chest Med 1996, 7, 183–197.10.1016/S0272-5231(05)70308-7Search in Google Scholar

13. Moore K.W., de Waal Malefyt R., Coffman R.L., O'Garra A.: Interleukin–10 and the interleukin-10 receptor. Ann Rev Immunol 2001, 19, 683–765.10.1146/annurev.immunol.19.1.68311244051Search in Google Scholar

14. Morikawa K., Watabe H., Araake M., Morikawa S.: Modulatory effect of antibiotics on cytokine production by human monocytes in vitro. Antimicrob Agent Chemother 1996, 40, 1366–1370.10.1128/AAC.40.6.13661633328726002Search in Google Scholar

15. Opal S.M., Esmon C.T.: Bench-to-bedside review: functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis. Critical Care 2003, 7, 23–38.Search in Google Scholar

16. Parveen Y., Calder P.C.: Cytokine production by human peripheral blood mononuclear cells: differential sensitivity to glutamine availability. Cytokine 1998, 10, 790–794.10.1006/cyto.1998.03589811533Search in Google Scholar

17. Pomorska-Mól M., Kwit K., Markowska-Daniel I., Pejsak Z.: The effect of doxycycline treatment on the postvaccinal immune response in pigs. Toxicol Appl Pharmacol 2014, 278, 31–38.10.1016/j.taap.2014.04.00624735996Search in Google Scholar

18. Pomorska-Mól M., Markowska-Daniel I., Kwit K., Czyżewska E., Dors A., Rachubik J., Pejsak Z.: Immune and inflammatory response in pigs during acute influenza caused by H1N1 swine influenza virus. Arch Virol 2014, 159, 2605–2614.10.1007/s00705-014-2116-1417311124846450Search in Google Scholar

19. Purswani M.U., Eckert S.J., Arora H.K., Moel G.J.: Effect of ciprofloxacin on lethal and sublethal challenge with endotoxin and on early cytokine response in a murine in vivo model. J Antimicrob Chemother 2002, 50, 51–58.10.1093/jac/dkf09112096006Search in Google Scholar

20. Schoevers E.J., van Leengoed L.A.M.G., Verheijden J.H.M., Niewold T.A.: Effects of enrofloxacin on porcine phagocytic function. Antimicrob Agent Chemother 1999, 43, 2138–2143.10.1128/AAC.43.9.21388943610471554Search in Google Scholar

21. Shalit I., Halperin D., Haite D., Levitov A., Romano J., Osherov N., Fabian I.: Anti-inflammatory effects of moxifloxacin on IL-8, IL-1beta and TNF-alpha secretion and NFkappaB and MAP–kinase activation in human monocytes stimulated with Aspergillus fumigatus. J Antimicrob Chemother 2006, 57, 230–235.10.1093/jac/dki44116352735Search in Google Scholar

22. Tsivkovskii R., Sabet M., Tarazi Z., Griffith D.C., Lomovskaya O., Dudley M.N.: Levofloxacin reduces inflammatory cytokine levels in human bronchial epithelia cells: implications for aerosol MP-376 (levofloxacin solution for inhalation) treatment of chronic pulmonary infections. FEMS Immunol Med Microbiol 2011, 61, 141–146.10.1111/j.1574-695X.2010.00755.x21073547Search in Google Scholar

23. Vaure C., Liu Y.: A comparative review of toll-like receptor 4 expression and functionality in different animal species. Front Immunol 2014, 5, 316.10.3389/fimmu.2014.00316409090325071777Search in Google Scholar

24. Williams A.C., Galley H.F., Watt A.M., Webster N.R.: Differential effects of three antibiotics on T helper cell cytokine expression. J Antimicrob Chemother 2005, 56, 502–506.10.1093/jac/dki25116006447Search in Google Scholar

25. Ziółkowski H., Jaroszewski J.J., Maślanka T., Grabowski T., Katolik K., Pawęska J., Siemianowska M., Jasiecka A., Markiewicz W., Spodniewska A.: Influence of oral co-administration of a preparation containing calcium and magnesium and food on enrofloxacin pharmacokinetics. Res Vet Sci 2014, 7, 99–104.10.1016/j.rvsc.2014.05.00524875062Search in Google Scholar