<abstract xmlns="http://www.w3.org/1999/xhtml"><p>An unstable plaque has a high risk of thrombosis and at the same time for a fast progression of the stenosis degree. Also, “high-risk plaque” and “thrombosis-prone plaque” are used as synonym terms for characterization of a vulnerable plaque. The imaging biomarkers for vulnerable coronary plaques are considered to be spotty calcifications, active remodeling, low-density atheroma and the presence of a ring-like attenuation pattern, also known as the napkin-ring sign. Computed cardiac tomography can determine the plaque composition by assessing the plaque density, which is measured in Hounsfield units (HU). The aim of this manuscript was to provide an update about the most frequently used biomarkers of vulnerability in a vulnerable plaque with the help of computed cardiac tomography.</p></abstract>

An unstable plaque has a high risk of thrombosis and at the same time for a fast progression of the stenosis degree. Also, “high-risk plaque” and “thrombosis-prone plaque” are used as synonym terms for characterization of a vulnerable plaque. The imaging biomarkers for vulnerable coronary plaques are considered to be spotty calcifications, active remodeling, low-density atheroma and the presence of a ring-like attenuation pattern, also known as the napkin-ring sign. Computed cardiac tomography can determine the plaque composition by assessing the plaque density, which is measured in Hounsfield units (HU). The aim of this manuscript was to provide an update about the most frequently used biomarkers of vulnerability in a vulnerable plaque with the help of computed cardiac tomography.

Computed Tomography Biomarkers of Vulnerable Coronary Plaques

University of Medicine and Pharmacy, Tîrgu Mureș,

Center of Advanced Research in Multimodality Cardiac Imaging, Cardio Med Medical Center, Tîrgu Mureș,

Journal of Interdisciplinary Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Computed Tomography Biomarkers of Vulnerable Coronary Plaques"}

An unstable plaque has a high risk of thrombosis and at the same time for a fast progression of the stenosis degree. Also, “high-risk plaque” and...

Computed Tomography Biomarkers of Vulnerable Coronary Plaques

Published Online: Dec 29, 2016

Page range: 263 - 266

Received: Nov 06, 2016

Accepted: Dec 04, 2016

DOI: https://doi.org/10.1515/jim-2016-0068

Keywords
unstable plaque, vulnerability biomarkers, CTA, VH-IVUS, OCT

© 2016 Tiberiu Nyulas et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Computed Tomography Biomarkers of Vulnerable Coronary Plaques

Published Online: Dec 29, 2016

Page range: 263 - 266

Received: Nov 06, 2016

Accepted: Dec 04, 2016

DOI: https://doi.org/10.1515/jim-2016-0068

Keywordsunstable plaque, vulnerability biomarkers, CTA, VH-IVUS, OCT

© 2016 Tiberiu Nyulas et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
unstable plaque, vulnerability biomarkers, CTA, VH-IVUS, OCT