Electrochemotherapy with bleomycin of different types of cutaneous tumours in a ferret (Mustela putorius furo)
Article Category: Research Article
Published Online: Dec 07, 2017
Page range: 98 - 104
Received: Oct 03, 2017
Accepted: Nov 05, 2017
DOI: https://doi.org/10.1515/raon-2017-0057
© 2018 Jozko Racnik, Tanja Svara, Marko Zadravec, Mitja Gombac, Maja Cemazar, Gregor Sersa, Natasa Tozon
This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background
Mast cell tumour, sebaceous gland adenoma, and less common squamous papilloma are skin tumours in ferrets (
Materials and methods
A 5-year-old castrated male ferret with two cutaneous masses, presenting 4 months apart and a 7-year-old spayed female ferret with two cutaneous masses, that appeared simultaneously on two locations are presented. In the first patient, both masses were diagnosed as mast cell tumours, and in the second patient, squamous papilloma and sebaceous adenoma were diagnosed. One session of ECT with bleomycin injected intratumourally was applied in all tumours.
Results
Complete response (CR) of all tumours was obtained, without recurrence during observation period of 15 months after ECT for first tumour and 11 months after ECT of the tumour located on the right hock in first patient, and 8 months after treatment for the second patient.
Conclusions
In present study, ECT with bleomycin proved to be safe and effective against different cutaneous tumours in ferrets. Due of good results, low cost and relatively easy procedure, ECT could be the treatment of choice instead of surgery for the selected skin tumours in ferrets.