Epidermal growth factor receptor variants in patients from Myanmar with lung adenocarcinoma
Article Category: Brief communication (original)
Published Online: Aug 04, 2020
Page range: 75 - 81
DOI: https://doi.org/10.1515/abm-2020-0011
Keywords
© 2020 Khine San Yin et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Background
Epidermal growth factor receptor (
Objectives
To describe the molecular epidemiology of
Methods
Histological diagnosis and categorization of biopsies collected from 66 patients (28–78 years) with lung cancer was conducted using a panel of antibodies including those to: TTF1, P40, synaptophysin, CK7, and napsin-A. Samples from patients with confirmed adenocarcinoma were tested for
Results
Histological types were adenocarcinoma (61%, 40/66), squamous cell carcinoma (24%, 16/66), neuroendocrine carcinoma (9%, 6/66), undifferentiated carcinoma (2%, 1/66), adenosquamous carcinoma (2%, 1/66), small cell anaplastic carcinoma (2%, 1/66), and pleomorphic sarcoma (2%, 1/66).
Conclusion
Knowledge of