Chronic Coronary Syndromes – the ESC Redefines the Concept of Stable Coronary Artery Disease

<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Background:</bold> Inflammation seems to be the most important trigger for atherosclerosis. Lower extremity artery disease (LEAD) and hypertension (HTN) are the most important atherosclerotic diseases. Total blood count-derived neutrophil-lymphocyte ratio (NLR) and red cell distribution width (RDW) have been proposed as inflammatory biomarkers in cardiovascular diseases. The aim of this study was to assess the correlation with LEAD and HTN.<bold>Material and methods:</bold> In total, 134 subjects were included in the study, divided into 2 groups as follows: group 1 – patients with LEAD and HTN; group 2 – subjects with HTN, without LEAD. Complete blood count (CBC) and lipid profile were determined. To assess peripheral artery disease, the ankle-brachial index (ABI) was measured with a handheld Doppler device (BiDop ES100V3 Hadeco®). We compared the inflammatory status between the groups with the use of white blood cell count (WBC), red cell distribution (RDW), and neutrophil-lymphocyte ratio (NLR).<bold>Results:</bold> In group 1, there was a significant negative correlation between the ABI and RDW (p = 0.04, r2 = –0.24, 95% CI: 0.4647–0.0013), as well as between the ABI and NLR (p = 0.001, r2 = –0.38, 95% CI: 0.5801–0.1592). In group 2, there was a positive correlation between NLR and total serum cholesterol levels (p = 0.003, 95% CI: 0.1274–0.5472, r2 = 0.12), as well as between NLR and triglyceride levels (p = 0.002, 95% CI: 0.1387–0.5552, r2 = 0.13).<bold>Conclusion:</bold> NLR and RDW could represent first-line investigations in patients with cardiovascular disease due their cost efficiency. They can also play a role in triaging patients with atherosclerotic disease, monitoring treatment response and prognosis of the disease.</abstract>

University of Medicine, Pharmacy, Science and Technology

Assessment of Inflammatory Status Based on Total Blood Count and Its Relationship to Cardiovascular Diseases

<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Background:</bold> Lymph node status in gastric cancer is known as an independent prognostic factor that guides the surgical and oncological treatment and independently influences long-term survival. Several studies suggest that the lymph node ratio has a greater importance in survival than the number of metastatic lymph nodes.<bold>Aim:</bold> The aim of this study was to evaluate the clinical and morphological factors that can influence the survival of gastric cancer patients, with an emphasis on nodal status and the lymph node ratio.<bold>Material and methods:</bold> We conducted a retrospective study in which 303 patients with gastric cancer admitted to the Department of Surgery of the Mureș County Hospital between 2008 and 2018 were screened for study enrolment. Data were obtained from the records of the department and from the histopathological reports. The examined variables included: age, gender, tumor localization, T stage, histological type, grade of differentiation, surgical procedure, lympho-vascular invasion, excised lymph nodes, metastatic lymph nodes, lymph node ratio. After screening, the study included a total number of 100 patients, for which follow-up data was available.<bold>Results:</bold> The mean age of the study population was 66.43 ± 10 years, and 71% were males. The average survival period was 21.42 months. Statistical analysis showed that the localization of the tumor (p = 0.021), vascular invasion (p ---lt---0.001), T (p = 0.004) and N (p ---lt---0.001) stages, type of surgery (partial gastrectomy 59% vs. total gastrectomy 41%, p = 0.005), as well as the lymph node ratio (p ---lt---0.001) were prognostic factors for survival in patients with gastric cancer undergoing surgical therapy.<bold>Conclusions:</bold> The survival of gastric cancer patients is significantly influenced by tumor localization, T stage, vascular invasion, type of surgery, N stage and the lymph node ratio based on univariate analysis. Also, the lymph node ratio proved to be an independent prognostic factor for survival.</abstract>

Study of Survival in Gastric Cancer with Emphasis on Lymph Node Status as an Independent Prognostic Factor

<abstract xmlns="http://www.w3.org/1999/xhtml">Congenital skin aplasia, known more as aplasia cutis congenita (ACC), is a rare congenital disease, characterized by absence of the skin, observed since birth, more often affecting the scalp and rarely the trunk or limbs. We report here for the first time a non-syndromic localized ACC, characterized by a small solitary area of skin atrophy on the cervical area in a healthy 3-day-old female infant.</abstract>

Nicolina Medical Centre, Department of Dermatology

Aplasia Cutis Congenita with Unusual Localization – Case Report

<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Introduction:</bold> Cystic congenital malformations of the seminal vesicle are unusual. More than half of them are associated with ipsilateral renal agenesis. This disease was first described by Zinner in 1914, and since then, more than 200 cases have been reported. Most of the patients with this congenital disease present few symptoms until the middle-age.<bold>Case presentation:</bold> A 61-year-old male was referred to the Urology Clinic with intermittent pain and sensibility in his lower left abdomen in the last 12 months accompanied by intermittent bowel obstruction. The digital rectal examination could not assess the prostate due to a rectal stenosis. On computed tomography and magnetic resonance imaging (MRI) a cystic tumor with close relations with the bladder wall and prostate, associated with left kidney agenesis was identified. The cystic tumor was surgically removed. The histopathological examination of the tumor revealed a multilocular seminal vesicle cyst, with a muscular wall.<bold>Conclusions:</bold> Seminal vesicle cysts combined with ipsilateral renal agenesis are rare urological anomalies. Imaging allows a comprehensive investigation of renal and seminal vesicle anomalies. MRI seems to better visualize cysts and differentiate them from ureteroceles, while the histopathological examination contributes to a correct diagnosis. A multidisciplinary team (urologists, radiologists, and morphologists) is necessary for the proper diagnosis of Zinner’s syndrome.</abstract>

“George Emil Palade” University of Medicine and Pharmacy, Science and Technology

County Clinical Hospital, “George Emil Palade” University of Medicine and Pharmacy, Science and Technology

Zinner’s Syndrome – The Value of Clinical Imaging and Morphopathological Findings for Diagnosis

Clinic of Pediatric Cardiology, Emergency Institute of Cardiovascular Diseases and Transplantation

Advanced Echocardiographic Assessment of Ebstein Anomaly in Children

AHEAD OF PRINT

Volume 8 (2023): Issue 3 (September 2023)

Volume 8 (2023): Issue 2 (June 2023)

Volume 8 (2023): Issue 1 (March 2023)

Volume 7 (2022): Issue 4 (December 2022)

Volume 7 (2022): Issue 3 (September 2022)

Volume 7 (2022): Issue 2 (June 2022)

Volume 7 (2022): Issue 1 (March 2022)

Volume 6 (2021): Issue 4 (December 2021)

Volume 6 (2021): Issue 3 (September 2021)

Volume 6 (2021): Issue 2 (June 2021)

Volume 6 (2021): Issue 1 (March 2021)

Volume 5 (2020): Issue 4 (December 2020)

Volume 5 (2020): Issue 3 (September 2020)

Volume 5 (2020): Issue 2 (June 2020)

Volume 5 (2020): Issue 1 (March 2020)

Volume 4 (2019): Issue 4 (December 2019)

Volume 4 (2019): Issue 3 (September 2019)

Volume 4 (2019): Issue 2 (June 2019)

Volume 4 (2019): Issue 1 (March 2019)

Volume 3 (2018): Issue 4 (December 2018)

Volume 3 (2018): Issue 3 (September 2018)

Volume 3 (2018): Issue 2 (June 2018)

Volume 3 (2018): Issue 1 (March 2018)

Volume 2 (2017): Issue 2 (June 2017)

Volume 2 (2017): Issue s4 (December 2017)

Volume 2 (2017): Issue 4 (December 2017)

Volume 2 (2017): Issue 3 (September 2017)

Volume 2 (2017): Issue s3 (May 2017)

Volume 2 (2017): Issue s1 (March 2017)

Volume 1 (2016): Issue 3 (December 2016)

Volume 1 (2016): Issue 2 (September 2016)

Volume 1 (2016): Issue 1 (June 2016)

Volume 1 (2016): Issue s2 (November 2016) Special Issue

Journal of Interdisciplinary Medicine

 The Journal of Interdisciplinary Medicine aims to publish top quality papers related to any fields of medicine that present an interdisciplinary dimension.  The journal will mainly focus on recent advances in the field of diagnosis and treatment of the most common situations encountered in the clinical or research practice. Interdisciplinary approaches will be extremely welcomed, presenting new advances in the approach of different pathologies from the perspective of various clinical fields.  The Journal of Interdisciplinary Medicine will publish high-quality basic and clinical research related to interdisciplinary medical fields, in a common approach that will integrate the clinical studies with the pre-clinical work dedicated to discovery of new mechanisms involved in the development and progression of a large spectrum of diseases.  The journal will try to provide the entire medical community with the perspective of the regional specifics in Central and Eastern European countries. The journal will primarily focus on publishing original research papers, but also other types of materials (such as review articles, case reports, state of the art papers, comments to editor, etc) will be extremely welcomed.  Rejection Rate:   30%   Archiving  Sciendo archives the contents of this journal in Portico - digital long-term preservation service of scholarly books, journals and collections.  Plagiarism Policy  The editorial board is participating in a growing community of Similarity Check System's users in order to ensure that the content published is original and trustworthy. Similarity Check is a medium that allows for comprehensive manuscripts screening, aimed to eliminate plagiarism and provide a high standard and quality peer-review process. 