<abstract xmlns="http://www.w3.org/1999/xhtml"><p><italic>The Malmö Diet Cancer (MDC) group is a population-based cohort (n = 28 098) among Malmö inhabitants,</italic><italic>aged 45-73 years at the time of baseline examinations in 1991-1996. Data collection</italic><italic>regarding socio-demography, anthropometry and lifestyle was extensive, and included nonfasting</italic><italic>blood samples. A high validity diet history was used to determine the usual diet. Information</italic><italic>regarding cancer morbidity and mortality from the Swedish Cancer Registry is assessed</italic><italic>yearly. Findings support the accepted hypotheses that a lifetime overexposure to sex hormones</italic><italic>(modern reproductive patterns) and obesity promote postmenopausal breast cancer. Also,</italic><italic>women with high intakes (compared to low intakes) of fibre, folic acid and fermented milk products</italic><italic>have lower risk of postmenopausal breast cancer. High intakes of alcohol and energyadjusted</italic><italic>fat are associated with increased risk. Also, high intakes of dried soup-sauce-powders</italic><italic>and of fried potatoes are associated with increased breast cancer risk. The MDC has two unique</italic><italic>assets: the high validity dietary data and the well maintained bio bank. Since a multitude and diverse</italic><italic>processes likely contribute to chronic disease the active use of biomarkers has become increasingly</italic><italic>important to nutrition epidemiology. Clear information about the diet-breast cancer link</italic><italic>is important to many women, because unlike reproductive factors diet is changeable throughout</italic><italic>the lifecycle.</italic></p></abstract>

The Malmö Diet Cancer (MDC) group is a population-based cohort (n = 28 098) among Malmö inhabitants,aged 45-73 years at the time of baseline examinations in 1991-1996. Data collectionregarding socio-demography, anthropometry and lifestyle was extensive, and included nonfastingblood samples. A high validity diet history was used to determine the usual diet. Informationregarding cancer morbidity and mortality from the Swedish Cancer Registry is assessedyearly. Findings support the accepted hypotheses that a lifetime overexposure to sex hormones(modern reproductive patterns) and obesity promote postmenopausal breast cancer. Also,women with high intakes (compared to low intakes) of fibre, folic acid and fermented milk productshave lower risk of postmenopausal breast cancer. High intakes of alcohol and energyadjustedfat are associated with increased risk. Also, high intakes of dried soup-sauce-powdersand of fried potatoes are associated with increased breast cancer risk. The MDC has two uniqueassets: the high validity dietary data and the well maintained bio bank. Since a multitude and diverseprocesses likely contribute to chronic disease the active use of biomarkers has become increasinglyimportant to nutrition epidemiology. Clear information about the diet-breast cancer linkis important to many women, because unlike reproductive factors diet is changeable throughoutthe lifecycle.

Diet And Breast Cancer: Experiences From The Malmö Diet Cancer Cohort

Department of Clinical Sciences in Malmö, Lund University; Clinical Research Centre (CRC) 60:13, Jan Waldenströms gata 35, SE-205 02 Malmö, SWEDEN

Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.

{"article-title":"Diet And Breast Cancer: Experiences From The Malmö Diet Cancer Cohort"}

The Malmö Diet Cancer (MDC) group is a population-based cohort (n = 28 098) among Malmö inhabitants,aged 45-73 years at the time of baseline examinations in...

Diet And Breast Cancer: Experiences From The Malmö Diet Cancer Cohort

Data publikacji: 29 gru 2012

Zakres stron: 101 - 103

DOI: https://doi.org/10.2478/v10046-012-0003-2

This content is open access.