A new approach to the spectrophotometric determination of metronidazole and tinidazole using p-dimethylaminobenzaldehyde

A. R. Katritzky, E. F. V. Scriven, S. Majumder, R. G. Akhmedova, N. G. Akhmedov and A. V. Vakulenko, Direct nitration of five membered heterocycles, ARKIVOC iii (2005) 179-191.10.3998/ark.5550190.0006.320Search in Google Scholar

A. Gennaro, Remington's Pharmaceutical Sciences, 18th ed., Mack Publishing Co., Easton 1993, pp. 1228-1230.Search in Google Scholar

R. J. Knox, R. C. Knight and D. I. Edwards, Interaction of nitroimidazole drugs with DNA in vitro: structure-activity relationships, Br. J. Cancer 44 (1981) 741-745.Search in Google Scholar

British Pharmacopoeia, Her Majesty's Stationery Office, London 2001.Search in Google Scholar

A. Z. A. Zuhri, S. I. Al-Khalil and M. S. Suleiman, Electrochemical reduction of metronidazole and its determination in pharmaceutical dosage forms by DC polarography, Anal. Lett. 19 (1986) 453-459.10.1080/00032718608064510Search in Google Scholar

G. O. El-Sayed, Polarographic determination of metronidazole in pharmaceutical formulations and urine, Microchem. J. 55 (1997) 110-114; DOI:10.1006/mchj.1996.1307.10.1006/mchj.1996.1307Search in Google Scholar

K. B. Mustapha, M. T. Odunola, M. Garba and O. Obodozie, Rapid, cost-effective liquid chromatograghic method for the determination of metronidazole in biological fluids, Afr. J. Biotech. 5 (2006) 1188-1190.Search in Google Scholar

S. S. Simoes, P. M. Everado, N. G. Everado, S. L. Wellington, N. T. M. Pablo, C. U. A. Mario, C. S. Edvan and B. N. Valberes, Flow injection determination of metronidazole through spectrophotometric measurement of the nitrite ion produced upon alkaline hydrolysis, J. Braz. Chem. Soc. 17 (2006) 609-613; DOI: 10.1590/S0103-50532006000300028.10.1590/S0103-50532006000300028Search in Google Scholar

B. H. Ahmed and J. O. Onah, Colorimetric determination of chloramphenicol and metronidazole in pharmaceutical formulations after Schiff-base formation with vanillin and anisaldehyde, Global J. Pure Appl. Sci. 9 (2003) 359-364.Search in Google Scholar

A. Rehman, A. S. Ijaz and A. Raz Spectrophotometric determination of metronidazole in pharmaceutical dosage forms using p-benzoquinone, J. Iran. Chem. Soc. 2 (2005) 197-202.10.1007/BF03245922Search in Google Scholar

C. S. P. Sastry, M. Aruna and A. R. M. Rao, Spectrophotometric determination of some antiamoebic and anthelmintic drugs with metol and chromium (VI), Talanta 35 (1988) 23-26; DOI: 10.1016/0039-9140(88)80006-7.10.1016/0039-9140(88)80006-7Search in Google Scholar

L. Lopez Martine, F. J. Luna Hernandez and P. L. Lopez Alba, Simple spectrophotometric determination of tinidazole in formulation and serum, Anal. Chim. Acta 340 (1997) 241-244; DOI: 10.1016/S0003-2670(96)00508-9.10.1016/S0003-2670(96)00508-9Search in Google Scholar

C. V. Prasad, V. Sripriya, R. N. Saha and P. Parimoo, Simultaneous determination of tinidazole, furazolidone and diloxanide furoate in a combined tablet preparation by second-derivative spectrophotometry, J. Pharm. Biomed. Anal. 21 (1999) 961-968; DOI: 10.1016/S0731-7085(99)00190-9.10.1016/S0731-7085(99)00190-9Search in Google Scholar

N. D. Dinesh, P. Nagaraja and K. S. Rangappa, A sensitive spectrophotometric assay for tinidazole and metronidazole using a Pd-C and formic acid reduction system, Turk. J. Chem. 28 (2004) 335-344Search in Google Scholar

P. Nagaraja, K. R. Sunitha, R. A. Vasantha and H. S. Yathirajan, Spectrophotometric determination of metronidazole and tinidazole in pharmaceutical preparations, J. Pharm. Biomed. Anal. 28 (2002) 527-53; DOI: 10.1016/S0731-7085(01)00685-9.10.1016/S0731-7085(01)00685-9Search in Google Scholar

K. Siddappa, M. Mallikarjun, P. T. Reddy and M. Tambe, Spectrophotometric determination of metroniodazole through Schiff's base system using vanillin and PDAB reagents in pharmaceutical preparations, Ecle. Quím. (Sao Paulo) 33 (2008) 41-46; DOI: 10.1590/S0100-46702008000400005.10.1590/S0100-46702008000400005Search in Google Scholar

O. A. Adegoke and C. E. Nwoke, Spectrophotometric determination of hydralazine using p-dimethylaminobenzaldehyde, J. Iran. Chem. Soc. 5 (2008) 316-323.10.1007/BF03246124Search in Google Scholar

H. T. Karnes and C. March, Precision, accuracy and data acceptance criteria in biopharmaceutical analysis, Pharm. Res. 10 (1993) 1420-1426.10.1023/A:1018958805795Search in Google Scholar

J. Rose, Advanced Physico-Chemical Experiments, Pitman, London 1964, p. 54.Search in Google Scholar

ICH Topic Q2 (R1), Validation of Analytical Procedures: Text and Methodology (CPMP/ICH/281/95); accessed June 30, 2008.Search in Google Scholar

United States Pharmacopoeia 24/National Formulary 19, US Pharmacopoeial Convention, Rockville 2000, p. 819.Search in Google Scholar