<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Lung pathologies such as edema, atelectasis or pneumonia are potentially life threatening conditions. Especially in critically ill and mechanically ventilated patients, an early diagnosis and treatment is crucial to prevent an Acute Respiratory Distress Syndrome [<xref ref-type="bibr" rid="j_joeb-2018-0013_ref_001_w2aab3b7d287b1b6b1ab2b2b1Aa">1</xref>]. Thus, continuous monitoring tool for the lung condition available at the bedside would be highly appreciated. One concept for this is Electrical Impedance Tomography (EIT). In EIT, an electrode belt of typically 16 or 32 electrodes is attached at the body surface and multiple impedance measurements are performed. From this, the conductivity change inside the body is reconstructed in a two-dimensional image. In various studies, EIT proved to be a useful tool for quantifying recruitment maneuvers, the assessment of the ventilation homogeneity, the detection of lung edema or perfusion monitoring [<xref ref-type="bibr" rid="j_joeb-2018-0013_ref_002_w2aab3b7d287b1b6b1ab2b2b2Aa">2</xref>, <xref ref-type="bibr" rid="j_joeb-2018-0013_ref_003_w2aab3b7d287b1b6b1ab2b2b3Aa">3</xref>, <xref ref-type="bibr" rid="j_joeb-2018-0013_ref_004_w2aab3b7d287b1b6b1ab2b2b4Aa">4</xref>, <xref ref-type="bibr" rid="j_joeb-2018-0013_ref_005_w2aab3b7d287b1b6b1ab2b2b5Aa">5</xref>]. Nevertheless, the main problem of EIT is the low spatial resolution (compared to CT) and the limitation to two dimensional images. In this paper, we try to address the latter issue: Instead of projecting conductivity changes onto a two-dimensional image, we adjust electrode positions to focus single tetrapolar measurements to specific, three-dimensional regions of interest. In earlier work, we defined guidelines to achieve this focusing [<xref ref-type="bibr" rid="j_joeb-2018-0013_ref_006_w2aab3b7d287b1b6b1ab2b2b6Aa">6</xref>, <xref ref-type="bibr" rid="j_joeb-2018-0013_ref_007_w2aab3b7d287b1b6b1ab2b2b7Aa">7</xref>]. In this paper, we demonstrate in simulations and in a water tank experiment that applying these guidelines can help to detect pathologies in specific lung regions.</p></abstract>

Lung pathologies such as edema, atelectasis or pneumonia are potentially life threatening conditions. Especially in critically ill and mechanically ventilated patients, an early diagnosis and treatment is crucial to prevent an Acute Respiratory Distress Syndrome [1]. Thus, continuous monitoring tool for the lung condition available at the bedside would be highly appreciated. One concept for this is Electrical Impedance Tomography (EIT). In EIT, an electrode belt of typically 16 or 32 electrodes is attached at the body surface and multiple impedance measurements are performed. From this, the conductivity change inside the body is reconstructed in a two-dimensional image. In various studies, EIT proved to be a useful tool for quantifying recruitment maneuvers, the assessment of the ventilation homogeneity, the detection of lung edema or perfusion monitoring [2, 3, 4, 5]. Nevertheless, the main problem of EIT is the low spatial resolution (compared to CT) and the limitation to two dimensional images. In this paper, we try to address the latter issue: Instead of projecting conductivity changes onto a two-dimensional image, we adjust electrode positions to focus single tetrapolar measurements to specific, three-dimensional regions of interest. In earlier work, we defined guidelines to achieve this focusing [6, 7]. In this paper, we demonstrate in simulations and in a water tank experiment that applying these guidelines can help to detect pathologies in specific lung regions.

Three-dimensional pulmonary monitoring using focused electrical impedance measurements

Journal of Electrical Bioimpedance

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Lung pathologies such as edema, atelectasis or pneumonia are potentially life threatening conditions. Especially in critically ill and mechanically ventilated...

Three-dimensional pulmonary monitoring using focused electrical impedance measurements

Data publikacji: 31 gru 2018

Zakres stron: 84 - 95

Otrzymano: 17 gru 2018

DOI: https://doi.org/10.2478/joeb-2018-0013

Słowa kluczowe
Electrical Impedance Analysis, Pulmonary, Monitoring, Regional Analysis

© 2018 Orschulik J, Pokee D, Menden T, Leonhardt S, Walter M published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Three-dimensional pulmonary monitoring using focused electrical impedance measurements

Data publikacji: 31 gru 2018

Zakres stron: 84 - 95

Otrzymano: 17 gru 2018

DOI: https://doi.org/10.2478/joeb-2018-0013

Słowa kluczoweElectrical Impedance Analysis, Pulmonary, Monitoring, Regional Analysis

© 2018 Orschulik J, Pokee D, Menden T, Leonhardt S, Walter M published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Słowa kluczowe
Electrical Impedance Analysis, Pulmonary, Monitoring, Regional Analysis