Analysis of α-Tocopherol in Tobacco and Cigarette Smoke

1 Riemenschneider, R.W., R.M. Speck, and E.G. Beinhart: Analysis and Fatty Acid Composition of Tobacco-Seed Oils; Oil Soap 22 (1945) 120–122. DOI: 10.1007/BF02635515 RiemenschneiderR.W. SpeckR.M. BeinhartE.G Analysis and Fatty Acid Composition of Tobacco-Seed Oils Oil Soap 22 1945 120 122 10.1007/BF02635515 Open DOISearch in Google Scholar

2 Rowland, R.L.: Flue-Cured Tobacco. III. Solanachromene and α-Tocopherol; J. Am. Chem. Soc. 80 (1958) 6130–6133. DOI: 10.1021/ja01555a057 RowlandR.L. Flue-Cured Tobacco. III. Solanachromene and α-Tocopherol J. Am. Chem. Soc 80 1958 6130 6133 10.1021/ja01555a057 Open DOISearch in Google Scholar

3 Rowland, R.L. and J.A. Giles: Flue-Cured Tobacco, V. Polyisoprenoid Compounds; Tob. Sci. 4 (1960) 29–32. RowlandR.L GilesJ.A Flue-Cured Tobacco, V. Polyisoprenoid Compounds Tob. Sci 4 1960 29 32 Search in Google Scholar

4 Quin, L.D.: Chemical Studies of Tobacco and its Smoke; Sel. Chim. 2 (1962) 37–62. QuinL.D. Chemical Studies of Tobacco and its Smoke Sel. Chim 2 1962 37 62 Search in Google Scholar

5 Steadman, R.L.: The Chemical Composition of Tobacco and Tobacco Smoke; Chem. Rev. 68 (1968) 153–207. DOI: 10.1021/cr60252a002 SteadmanR.L. The Chemical Composition of Tobacco and Tobacco Smoke Chem. Rev 68 1968 153 207 10.1021/cr60252a002 4868017 Open DOISearch in Google Scholar

6 Huber, G.L.: Physical, Chemical, and Biological Properties of Tobacco, Cigarette Smoke, and Other Tobacco Products; in Tobacco and Smoking Cessation, edited by G.L. Huber, Sem. Resp. Med. 10 (1989) pp 297–332. HuberG.L. Physical, Chemical, and Biological Properties of Tobacco, Cigarette Smoke, and Other Tobacco Products; in Tobacco and Smoking Cessation edited by HuberG.L. Sem. Resp. Med 10 1989 297 332 10.1055/s-2007-1006184 Search in Google Scholar

7 Dong, J.Z, S.C. Moldoveanu, and J.H. Lauterbach: A Parallel Study Between Leaf Chemistry and Particulate-Phase Smoke Chemistry; Presented at the 47^th Tobacco Science Research Conference (TSRC), Program Booklet and Abstracts Vol. 47, Paper 6, 1993, p 27. DongJ.Z MoldoveanuS.C. LauterbachJ.H A Parallel Study Between Leaf Chemistry and Particulate-Phase Smoke Chemistry Presented at the 47^th Tobacco Science Research Conference (TSRC), Program Booklet and Abstracts 47 Paper 6 1993 27 Search in Google Scholar

8 Tso, T.C.: Production, Physiology and Biochemistry of Tobacco Plant; Ideals Inc., Beltsville, MD, USA, 1990. ISBN 10: 1878670018 TsoT.C. Production, Physiology and Biochemistry of Tobacco Plant Ideals Inc. Beltsville, MD, USA 1990 ISBN 10: 1878670018 Search in Google Scholar

9 Rodgman, A.: The Composition of Cigarette Smoke: Problems with Lists of Tumorigens; Beitr. Tabakforsch. Int. 20 (2003) 403–437. DOI: 10.2478/cttr-2013-0758 RodgmanA. The Composition of Cigarette Smoke: Problems with Lists of Tumorigens Beitr. Tabakforsch. Int 20 2003 403 437 10.2478/cttr-2013-0758 Open DOISearch in Google Scholar

10 Moldoveanu, S.C., J.W. Wilkins, and W.M. Coleman III: Evaluation of the Retention by Humans of Several Cigarette Smoke Constituents; Presented at the 60^th Tobacco Science Research Conference (TSRC), Program Booklet and Abstracts Vol. 60, Paper 58, 2006, p 51. MoldoveanuS.C. WilkinsJ.W. ColemanW.MIII Evaluation of the Retention by Humans of Several Cigarette Smoke Constituents Presented at the 60^th Tobacco Science Research Conference (TSRC), Program Booklet and Abstracts 60 Paper 58 2006 51 Search in Google Scholar

11 Green, C.R., J.N. Schumacher, R.A. Lloyd Jr, and A. Rodgman: Comparisons of the Composition of Tobacco Smoke and the Smokes from Various Tobacco Substitutes; Beitr. Tabakforsch. Int. 22 (2007) 258–289. DOI: 10.2478/cttr-2013-0833 GreenC.R. SchumacherJ.N. LloydR.A.Jr RodgmanA Comparisons of the Composition of Tobacco Smoke and the Smokes from Various Tobacco Substitutes Beitr. Tabakforsch. Int 22 2007 258 289 10.2478/cttr-2013-0833 Open DOISearch in Google Scholar

12 Moldoveanu, S.C. and F.K. St.Charles: Differences in the Chemical Composition of the Particulate Phase of Inhaled and Exhaled Cigarette Mainstream Smoke; Beitr. Tabakforsch. Int. 22 (2007) 290–302. DOI: 10.2478/cttr-2013-0834 MoldoveanuS.C St.CharlesF.K Differences in the Chemical Composition of the Particulate Phase of Inhaled and Exhaled Cigarette Mainstream Smoke Beitr. Tabakforsch. Int 22 2007 290 302 10.2478/cttr-2013-0834 Open DOISearch in Google Scholar

13 Schmeltz, I., A. de Paolis, and D. Hoffmann: Phytosterols in Tobacco: Quantitative Analysis and Fate in Tobacco Combustion; Beitr. Tabakforsch. 8 (1975) 211–218. DOI: 10.2478/cttr-2013-0382 SchmeltzI. de PaolisA. HoffmannD Phytosterols in Tobacco: Quantitative Analysis and Fate in Tobacco Combustion Beitr. Tabakforsch 8 1975 211 218 10.2478/cttr-2013-0382 Open DOISearch in Google Scholar

14 Risner, C.H.: The Determination of α-Tocopherol in Tobacco and Mainstream Tobacco Smoke; Presented at the 50^th Tobacco Science Research Conference (TSRC), Program Booklet and Abstracts Vol. 50, Paper 46, 1996, p 47. RisnerC.H. The Determination of α-Tocopherol in Tobacco and Mainstream Tobacco Smoke Presented at the 50^th Tobacco Science Research Conference (TSRC), Program Booklet and Abstracts 50 Paper 46 1996 47 Search in Google Scholar

15 Risner, C.H. and P.R. Nelson: The Determination of α-Tocopherol in Environmental Tobacco Smoke; Presented at the 51^st Tobacco Science Research Conference (TSRC), Program Booklet and Abstracts Vol. 51, Paper 48, 1997, p 54. RisnerC.H NelsonP.R The Determination of α-Tocopherol in Environmental Tobacco Smoke Presented at the 51^st Tobacco Science Research Conference (TSRC), Program Booklet and Abstracts 51 Paper 48 1997 54 10.1093/chromsci/36.2.809487671 Search in Google Scholar

16 Lampi, A.-M.: Analysis of Tocopherols and Tocotrienols by HPLC; AOAC Lipid library. Available at: https://lipidlibrary.aocs.org/lipid-analysis/selected-topics-in-the-analysis-of-lipids/analysis-of-tocopherols-and-tocotrienols-by-hplc (accessed July, 2020) LampiA.-M. Analysis of Tocopherols and Tocotrienols by HPLC AOAC Lipid library Available at: https://lipidlibrary.aocs.org/lipid-analysis/selected-topics-in-the-analysis-of-lipids/analysis-of-tocopherols-and-tocotrienols-by-hplc (accessed July, 2020) 10.21748/lipidlibrary.40389 Search in Google Scholar

17 Eitenmiller, R.R. and J. Lee: Vitamin E: Food Chemistry, Composition, and Analysis; CRC Press, New York, NY, USA, 2004. ISBN: 0203970144, 9780203970140 EitenmillerR.R LeeJ Vitamin E: Food Chemistry, Composition, and Analysis CRC Press New York, NY, USA 2004 ISBN: 0203970144, 9780203970140 10.1201/9780203970140 Search in Google Scholar

18 Ng, M.H. and C.Y. May: Chromatographic Analysis of Tocopherols and Tocotrienols in Palm Oil; J. Chrom. Sci. 50 (2012) 283–286. DOI: 10.1093/chromsci/bms002 NgM.H MayC.Y Chromatographic Analysis of Tocopherols and Tocotrienols in Palm Oil J. Chrom. Sci 50 2012 283 286 10.1093/chromsci/bms002 Open DOISearch in Google Scholar

19 Mayne, S.T. and R.S. Parker: HPLC Analysis of Vitamin E by Conversion to α-Tocopheryl Acetate in Samples Containing Canthaxanthin or Other Coeluting Compounds; J. Agric. Food Chem. 36 (1988) 483–485. DOI: 10.1021/jf00081a019 MayneS.T ParkerR.S HPLC Analysis of Vitamin E by Conversion to α-Tocopheryl Acetate in Samples Containing Canthaxanthin or Other Coeluting Compounds J. Agric. Food Chem 36 1988 483 485 10.1021/jf00081a019 Open DOISearch in Google Scholar

20 Moldoveanu, S.C.: Profiling of Lipids from Fruit and Seed Extracts; in Sea Food, Marine Based Dietary Supplement, Fruit and Seed, edited by Su Chen, Chapter 5, 1–19 Lipidomics, Transworld Research, Kerala, India (2012). ISBN: 978-81-7895-573-5 MoldoveanuS.C. Profiling of Lipids from Fruit and Seed Extracts; in Sea Food, Marine Based Dietary Supplement, Fruit and Seed edited by ChenSu Chapter 5, 1 19 Lipidomics, Transworld Research Kerala, India 2012 ISBN: 978-81-7895-573-5 Search in Google Scholar

21 Rupérez, F.J., D. Martín, E. Herrera, and C. Barbas: Chromatographic Analyses of Alpha-Tocopherol and Related Compounds in Various Matrices; J. Chromatogr. A 935 (2001) 45–69. DOI: 10.1016/s0021-9673(01)01101-3 RupérezF.J. MartínD. HerreraE. BarbasC Chromatographic Analyses of Alpha-Tocopherol and Related Compounds in Various Matrices J. Chromatogr. A 935 2001 45 69 10.1016/s0021-9673(01)01101-3 Open DOISearch in Google Scholar

22 Xu, Z.: Analysis of Tocopherols and Tocotrienols; Current Protocols in Food Analytical Chemistry 4 (2002) D1.5.1–D1.5.12. DOI: 10.1002/0471142913.fad0105s04 XuZ. Analysis of Tocopherols and Tocotrienols Current Protocols in Food Analytical Chemistry 4 2002 D1.5.1 D1.5.12 10.1002/0471142913.fad0105s04 Open DOISearch in Google Scholar

23 Ryynänen, M., A. Lampi, P. Salo-Väänänen, V. Ollilainen, and V. Piironen: A Small-Scale Sample Preparation Method With HPLC Analysis for Determination of Tocopherols and Tocotrienols in Cereals; J. Food Comp. Anal. 17 (2004) 749–765. DOI: 10.1016/j.jfca.2003.09.014 RyynänenM. LampiA. Salo-VäänänenP. OllilainenV. PiironenV A Small-Scale Sample Preparation Method With HPLC Analysis for Determination of Tocopherols and Tocotrienols in Cereals J. Food Comp. Anal 17 2004 749 765 10.1016/j.jfca.2003.09.014 Open DOISearch in Google Scholar

24 Panfili, G., A. Fratianni, and M. Irano: Normal Phase High-Performance Liquid Chromatography Method for the Determination of Tocopherols and Tocotrienols in Cereals; J. Agric. Food Chem. 51 (2003) 3940–3944. DOI: 10.1021/jf030009v PanfiliG. FratianniA. IranoM Normal Phase High-Performance Liquid Chromatography Method for the Determination of Tocopherols and Tocotrienols in Cereals J. Agric. Food Chem 51 2003 3940 3944 10.1021/jf030009v 12822927 Open DOISearch in Google Scholar

25 Gómez-Coronado, D.J.M., E. Ibañez, F.J. Rupérez, and C. Barbas: Tocopherol Measurement in Edible Products of Vegetable Origin; J. Chromatogr. A 1054 (2004) 227–233. DOI: 10.1016/j.chroma.2004.08.072 Gómez-CoronadoD.J.M. IbañezE. RupérezF.J. BarbasC Tocopherol Measurement in Edible Products of Vegetable Origin J. Chromatogr. A 1054 2004 227 233 10.1016/j.chroma.2004.08.072 15553148 Open DOISearch in Google Scholar

26 Kadioglu, Y., F. Demirkaya, and A.K. Demirkaya: Quantitative Determination of Underivatized α-Tocopherol in Cow Milk, Vitamin and Multivitamin Drugs by GC-FID; Chromatographia 70 (2009) 665–670. DOI: 10.1365/s10337-009-1184-y KadiogluY. DemirkayaF. DemirkayaA.K Quantitative Determination of Underivatized α-Tocopherol in Cow Milk, Vitamin and Multivitamin Drugs by GC-FID Chromatographia 70 2009 665 670 10.1365/s10337-009-1184-y Open DOISearch in Google Scholar

27 Nielsen, M.M. and A. Hansen: Rapid High-Performance Liquid Chromatography Determination of Tocopherols and Tocotrienols in Cereals; Cereal Chem. 85 (2008) 248–251. DOI: 10.1094/CCHEM-85-2-0248 NielsenM.M HansenA Rapid High-Performance Liquid Chromatography Determination of Tocopherols and Tocotrienols in Cereals Cereal Chem 85 2008 248 251 10.1094/CCHEM-85-2-0248 Open DOISearch in Google Scholar

28 Lanina, S.A., P. Toledo, S. Sampels, A. Kamal-Eldin, and J.A. Jastrebova: Comparison of Reversed-Phase Liquid Chromatography-Mass Spectrometry with Electrospray and Atmospheric Pressure Chemical Ionization for Analysis of Dietary Tocopherols; J. Chromatogr. A 1157 (2007) 159–170. DOI: 10.1016/j.chroma.2007.04.058 LaninaS.A. ToledoP. SampelsS. Kamal-EldinA. JastrebovaJ.A Comparison of Reversed-Phase Liquid Chromatography-Mass Spectrometry with Electrospray and Atmospheric Pressure Chemical Ionization for Analysis of Dietary Tocopherols J. Chromatogr. A 1157 2007 159 170 10.1016/j.chroma.2007.04.058 Open DOISearch in Google Scholar

29 Bustamante-Rangel, M., M.M. Delgado-Zamarreño, A. Sánchez-Pérez, and R. Carabias-Martínez: Determination of Tocopherols and Tocotrienols in Cereals by Pressurized Liquid Extraction-Liquid Chromatography-Mass Spectrometry; Anal. Chim. Acta 587 (2007) 216–221. DOI: 10.1016/j.aca.2007.01.049 Bustamante-RangelM. Delgado-ZamarreñoM.M. Sánchez-PérezA. Carabias-MartínezR Determination of Tocopherols and Tocotrienols in Cereals by Pressurized Liquid Extraction-Liquid Chromatography-Mass Spectrometry Anal. Chim. Acta 587 2007 216 221 10.1016/j.aca.2007.01.049 Open DOISearch in Google Scholar

30 Kamal-Eldi, A., S. Görgen, J. Pettersson, and A.M. Lampi: Normal-Phase High-Performance Liquid Chromatography of Tocopherols and Tocotrienols. Comparison of Different Chromatographic Columns; J. Chromatogr. A 881 (2000) 217–227. DOI: 10.1016/s0021-9673(99)01346-1 Kamal-EldiA. GörgenS. PetterssonJ. LampiA.M Normal-Phase High-Performance Liquid Chromatography of Tocopherols and Tocotrienols. Comparison of Different Chromatographic Columns J. Chromatogr. A 881 2000 217 227 10.1016/s0021-9673(99)01346-1 Open DOISearch in Google Scholar

31 Moltó-Puigmartí, C., A.I. Castellote, and M.C. López-Sabater: Ultra-High-Pressure Liquid Chromatographic Method for the Analysis of Tocopherols in Human Colostrum and Milk; J. Chromatogr. A 1216 (2009) 4388–4394. DOI:10.1016/j.chroma.2009.02.088 Moltó-PuigmartíC. CastelloteA.I. López-SabaterM.C Ultra-High-Pressure Liquid Chromatographic Method for the Analysis of Tocopherols in Human Colostrum and Milk J. Chromatogr. A 1216 2009 4388 4394 10.1016/j.chroma.2009.02.088 19368930 Open DOISearch in Google Scholar

32 Khan, A., M.I. Khan, Z. Iqbal, Y. Shah, L. Ahmad, and D.G. Watson: An Optimized and Validated RP-HPLC/UV Detection Method for Simultaneous Determination of All-Trans-Retinol (Vitamin A) and Alpha-Tocopherol (Vitamin E) in Human Serum: Comparison of Different Particulate Reversed-Phase HPLC Columns; J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 878 (2010) 2339–2347. DOI: 10.1016/j.jchromb.2010.07.009 KhanA. KhanM.I. IqbalZ. ShahY. AhmadL. WatsonD.G An Optimized and Validated RP-HPLC/UV Detection Method for Simultaneous Determination of All-Trans-Retinol (Vitamin A) and Alpha-Tocopherol (Vitamin E) in Human Serum: Comparison of Different Particulate Reversed-Phase HPLC Columns J. Chromatogr. B Analyt. Technol. Biomed. Life Sci 878 2010 2339 2347 10.1016/j.jchromb.2010.07.009 20696624 Open DOISearch in Google Scholar

33 Gentili, A. and F. Caretti: Evaluation of a Method Based on Liquid Chromatography-Diode Array Detector-Tandem Mass Spectrometry for a Rapid and Comprehensive Characterization of the Fat-Soluble Vitamin and Carotenoid Profile of Selected Plant Foods; J. Chromatogr. A 1218 (2011) 684–697. DOI: 10.1016/j.chroma.2010.12.001 GentiliA CarettiF Evaluation of a Method Based on Liquid Chromatography-Diode Array Detector-Tandem Mass Spectrometry for a Rapid and Comprehensive Characterization of the Fat-Soluble Vitamin and Carotenoid Profile of Selected Plant Foods J. Chromatogr. A 1218 2011 684 697 10.1016/j.chroma.2010.12.001 21190690 Open DOISearch in Google Scholar

34 Hryniewicka, M., A. Karpinska, M. Kijewska, M.J. Turkowicz, and J. Karpinska: LC/MS/MS Analysis of α-Tocopherol and Coenzyme Q₁₀ Content in Lyophilized Royal Jelly, Beebread and Drone Homogenate; J. Mass Spectrom. 51 (2016) 1023–1029. DOI: 10.1002/jms.3821. HryniewickaM. KarpinskaA. KijewskaM. TurkowiczM.J. KarpinskaJ LC/MS/MS Analysis of α-Tocopherol and Coenzyme Q₁₀ Content in Lyophilized Royal Jelly, Beebread and Drone Homogenate J. Mass Spectrom 51 2016 1023 1029 10.1002/jms.3821 27459546 Open DOISearch in Google Scholar

35 Jiang, Q., T. Xu, J. Huang, A.S. Jannasch, B. Cooper, and C. Yang: Analysis of Vitamin E Metabolites Including Carboxychromanols and Sulfated Derivatives Using LC/MS/MS; J. Lipid Res. 56 (2015) 2217–2225. DOI: 10.1194/jlr.d061663 JiangQ. XuT. HuangJ. JannaschA.S. CooperB. YangC Analysis of Vitamin E Metabolites Including Carboxychromanols and Sulfated Derivatives Using LC/MS/MS J. Lipid Res 56 2015 2217 2225 10.1194/jlr.d061663 461740826351363 Open DOISearch in Google Scholar

36 Zhou, W.: Alpha-Tocopherol Analysis by HPLC; Protocol Exchange Method Article Biochemistry (2011). Available at: https://assets.researchsquare.com/files/nprot-2154/v1/manuscript.pdf (assecced July 2020) DOI: 10.1038/protex.2011.244 ZhouW. Alpha-Tocopherol Analysis by HPLC Protocol Exchange Method Article Biochemistry 2011 Available at: https://assets.researchsquare.com/files/nprot-2154/v1/manuscript.pdf (assecced July 2020) 10.1038/protex.2011.244 Open DOISearch in Google Scholar

37 Cherian S.V., A.Kumar, and R.M. Estrada-Y-Martin: E-Cigarette or Vaping-Product Associated Lung Injury. A Review; Am. J. Med. 133 (2020) 657–663. DOI: 10.1016/j.amjmed.2020.02.004 CherianS.V. KumarA. Estrada-Y-MartinR.M. E-Cigarette or Vaping-Product Associated Lung Injury. A Review Am. J. Med 133 2020 657 663 10.1016/j.amjmed.2020.02.004 32179055 Open DOISearch in Google Scholar

38 Lanzarotta A., T.M. Falconer, R. Flurer, and R.A. Wilson: Hydrogen Bonding Between Tetrahydrocannabinol and Vitamin E Acetate in Unvaped, Aerosolized, and Condensed Aerosol e-Liquids; Anal. Chem. 92 (2020) 2374–2378. DOI: 10.1021/acs.analchem.9b05536 LanzarottaA. FalconerT.M. FlurerR. WilsonR.A Hydrogen Bonding Between Tetrahydrocannabinol and Vitamin E Acetate in Unvaped, Aerosolized, and Condensed Aerosol e-Liquids Anal. Chem 92 2020 2374 2378 10.1021/acs.analchem.9b05536 31951379 Open DOISearch in Google Scholar

39 Cao D.J., K. Aldy, S. Hsu, M. McGetrick, G. Verbeck, I. De Silva, and S.-Y. Feng: Review of Health Consequences of Electronic Cigarettes and the Outbreak of Electronic Cigarette, or Vaping, Product Use-Associated Lung Injury; J. Med. Toxicol. 16 (2020) 295–310. DOI: 10.1007/s13181-020-00772-w CaoD.J. AldyK. HsuS. McGetrickM. VerbeckG. De SilvaI. FengS.-Y Review of Health Consequences of Electronic Cigarettes and the Outbreak of Electronic Cigarette, or Vaping, Product Use-Associated Lung Injury J. Med. Toxicol 16 2020 295 310 10.1007/s13181-020-00772-w 732008932301069 Open DOISearch in Google Scholar

40 International Organization for Standardization (ISO): ISO 3308:2012 Routine Analytical Cigarette Smoking Machine – Definitions and Standard Conditions; ISO, Geneva, Switzerland, 2012. International Organization for Standardization (ISO) ISO 3308:2012 Routine Analytical Cigarette Smoking Machine – Definitions and Standard Conditions ISO Geneva, Switzerland 2012 Search in Google Scholar

41 International Organization for Standardization (ISO): ISO 4387:2019 Cigarettes – Determination of Total and Nicotine Free Dry Particulate Matter Using a Routine Analytical Smoking Machine; ISO, Geneva, Switzerland, 2019. International Organization for Standardization (ISO) ISO 4387:2019 Cigarettes – Determination of Total and Nicotine Free Dry Particulate Matter Using a Routine Analytical Smoking Machine ISO Geneva, Switzerland 2019 Search in Google Scholar

42 Moldoveanu, S.C. and V. David: Selection of the HPLC Method in Chemical Analysis; 1^st Edition, Elsevier, Amsterdam, NL, 2016, p.21. ISBN: 9780128037119 MoldoveanuS.C DavidV Selection of the HPLC Method in Chemical Analysis 1st Edition Elsevier Amsterdam, NL 2016 21 ISBN: 9780128037119 Search in Google Scholar