This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Global initiative for asthma. Global strategy for asthma management and prevention, 2016. Available from: www.ginasthma.org.Global initiative for asthma. Global strategy for asthma management and prevention2016Available fromwww.ginasthma.orgSearch in Google Scholar
Baren JM, Zorc JJ. Contemporary approach to the emergency department management of pediatric asthma. Emerg Med Clin North Am. 2002; 20(1): 115-138.BarenJMZorcJJContemporary approach to the emergency department management of pediatric asthmaEmerg Med Clin North Am2002201115–13810.1016/S0733-8627(03)00054-3Search in Google Scholar
Martin AC, Zhang G, Rueter K, Geelhoed G, Goldblatt J, Laing I, et al. β2-Adrenoceptor polymorphisms predict response to β2-agonists in children with acute asthma. J Asthma. 2008; 45(5): 383-388.MartinACZhangGRueterKGeelhoedGGoldblattJLaingIβ2-Adrenoceptor polymorphisms predict response to β2-agonists in children with acute asthmaJ Asthma2008455383–38810.1080/0277090080197179218569231Search in Google Scholar
Barnes KC. Genetic studies of the etiology of asthma. Proc Am Thorac Soc. 2011; 8(4): 143-148.BarnesKCGenetic studies of the etiology of asthmaProc Am Thorac Soc201184143–14810.1513/pats.201103-030MS313183021543791Search in Google Scholar
Contopoulos-Ioannidis DG, Manoli EN, Ioannidis JP. Meta-analysis of the association of β2-adrenergic receptor polymorphisms with asthma phenotypes. J Allergy Clin Immunol. 2005; 115(5): 963-972.Contopoulos-IoannidisDGManoliENIoannidisJPMeta-analysis of the association of β2-adrenergic receptor polymorphisms with asthma phenotypesJ Allergy Clin Immunol20051155963–97210.1016/j.jaci.2004.12.111915867853Search in Google Scholar
Finkelstein Y, Bournissen FG, Hutson JR, Shannon M. Polymorphism of the ADRB2 gene and response to inhaled β-agonists in children with asthma: A meta-analysis. J Asthma. 2009; 46(9): 900-905.FinkelsteinYBournissenFGHutsonJRShannonMPolymorphism of the ADRB2 gene and response to inhaled β-agonists in children with asthma: A meta-analysisJ Asthma2009469900–90510.3109/0277090090319996119905915Search in Google Scholar
de Paiva AC, Marson FA, Ribeiro JD, Bertuzzo CS. Asthma: Gln27Glu and Arg16Gly polymorphisms of the β2-adrenergic receptor gene as risk factors. Allergy Asthma Clin Immunol. 2014; 10(1): 8.dePaiva ACMarsonFARibeiroJDBertuzzoCSAsthma: Gln27Glu and Arg16Gly polymorphisms of the β2-adrenergic receptor gene as risk factorsAllergy Asthma Clin Immunol2014101810.1186/1710-1492-10-8393055424499171Search in Google Scholar
Marson FA, Bertuzzo CS, Ribeiro AF, Ribeiro JD. Polymorphisms in ADRB2 gene can modulate the response to bronchodilators and the severity of cystic fibrosis. BMC Pulm Med. 2012; 12: 50.MarsonFABertuzzoCSRibeiroAFRibeiroJDPolymorphisms in ADRB2 gene can modulate the response to bronchodilators and the severity of cystic fibrosisBMC Pulm Med2012125010.1186/1471-2466-12-50355840522950544Search in Google Scholar
Chung LP, Waterer G, Thompson PJ. Pharmacogenetics of β2 adrenergic receptor gene polymorphisms, long-acting β-agonists and asthma. Clin Exp Allergy. 2011; 41(3): 312-326.ChungLPWatererGThompsonPJPharmacogenetics of β2 adrenergic receptor gene polymorphisms, long-acting β-agonists and asthmaClin Exp Allergy2011413312–32610.1111/j.1365-2222.2011.03696.x21294785Search in Google Scholar
Birbian N, Singh J, Jindal SK, Singla N. Association of β2-adrenergic receptor polymorphisms with asthma in a North Indian population. Lung. 2012; 190(5): 497-504.BirbianNSinghJJindalSKSinglaNAssociation of β2-adrenergic receptor polymorphisms with asthma in a North Indian populationLung20121905497–50410.1007/s00408-012-9407-722821646Search in Google Scholar
Karam RA, Sabbah NA, Zidan HE, Rahman HM. Association between genetic polymorphisms of β2 adre-nergic receptors and nocturnal asthma in Egyptian children. J Investig Allergol Clin Immunol. 2013; 23(4): 262-266.KaramRASabbahNAZidanHERahmanHMAssociation between genetic polymorphisms of β2 adre-nergic receptors and nocturnal asthma in Egyptian childrenJ Investig Allergol Clin Immunol2013234262–266Search in Google Scholar
Petrovic-Stanojevic N, Topic A, Nikolic A, Stan-kovic M, Dopudja-Pantic V, Milenkovic B, et al. Polymorphisms of β2-adrenergic receptor gene in serbian asthmatic adults: Effects on response to β-agonists. Mol Diagn Ther. 2014; 18(6): 639-646.Petrovic-StanojevicNTopicANikolicAStan-kovicMDopudja-PanticVMilenkovicBPolymorphisms of β2-adrenergic receptor gene in serbian asthmatic adults: Effects on response to β-agonistsMol Diagn Ther2014186639–64610.1007/s40291-014-0116-125074500Search in Google Scholar
American Thoracic Society. Standardization of spirometry, 1994 update. Am J Respir Crit Care Med. 1995; 152(3): 1107-1136.American Thoracic SocietyStandardization of spirometry, 1994 updateAm J Respir Crit Care Med199515231107–113610.1164/ajrccm.152.3.76637927663792Search in Google Scholar
Contopoulos-Ioannidis DG, Manoli EN, Ioannidis JP. Meta-analysis of the association of β2-adrenergic receptor polymorphisms with asthma phenotypes. J Allergy Clin Immunol. 2005; 115(5): 963-972.Contopoulos-IoannidisDGManoliENIoannidisJPMeta-analysis of the association of β2-adrenergic receptor polymorphisms with asthma phenotypesJ Allergy Clin Immunol20051155963–97210.1016/j.jaci.2004.12.111915867853Search in Google Scholar
Salama MS, Ashaat NA, Hamad AA. Genetic association between common β-2 adrenoreceptor polymorphism and asthma severity in school-age children. Egyptian J Med Hum Genet. 2012; 12(2): 151-156.SalamaMSAshaatNAHamadAAGenetic association between common β-2 adrenoreceptor polymorphism and asthma severity in school-age childrenEgyptian J Med Hum Genet2012122151–15610.1016/j.ejmhg.2011.07.003Search in Google Scholar
Moore PE, Laporte JD, Abraham JH, Schwartzman IN, Yandava CN, Silverman ES, et al. Polymorphism of the β2-adrenergic receptor gene and desensitization in human airway smooth muscle. Am J Respir Crit Care Med. 2000; 162(6): 2117-2124.MoorePELaporteJDAbrahamJHSchwartzmanINYandavaCNSilvermanESPolymorphism of the β2-adrenergic receptor gene and desensitization in human airway smooth muscleAm J Respir Crit Care Med200016262117–212410.1164/ajrccm.162.6.990904611112125Search in Google Scholar
Green SA, Turki J, Bejarano P, Hall IP, Liggett SB. Influence of β2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells. Am J Respir Cell Mol Biol. 1995; 13(1): 25-33.GreenSATurkiJBejaranoPHallIPLiggettSBInfluence of β2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cellsAm J Respir Cell Mol Biol199513125–3310.1165/ajrcmb.13.1.75989367598936Search in Google Scholar
Asano K, Yamada-Yamasawa W, Kudoh H, Matsuzaki T, Nakajima T, Hakuno H, et al. Association between β-adrenoceptor gene polymorphisms and relative response to β2-agonists and anticholinergic drugs in Japanese asthmatic patients. Respirology. 2010; 15(5): 849-854.AsanoKYamada-YamasawaWKudohHMatsuzakiTNakajimaTHakunoHAssociation between β-adrenoceptor gene polymorphisms and relative response to β2-agonists and anticholinergic drugs in Japanese asthmatic patientsRespirology2010155849–85410.1111/j.1440-1843.2010.01786.x20546196Search in Google Scholar
Fu WP, Zhao ZH, Zhong L, Sun C, Fang LZ, Liu L, et al. Relationship between polymorphisms in the 5 leader cistron, positions 16 and 27 of the adrenergic β2 receptor gene and asthma in a Han population from southwest China. Respirology. 2011; 16(8): 1221-1227.FuWPZhaoZHZhongLSunCFangLZLiuLRelationship between polymorphisms in the 5 leader cistron, positions 16 and 27 of the adrenergic β2 receptor gene and asthma in a Han population from southwest ChinaRespirology20111681221–122710.1111/j.1440-1843.2011.02028.x21801278Search in Google Scholar
Martinez FD, Graves PE, Baldini M, Solomon S, Erickson R. Association between polymorphisms of ADRB2 and response to albuterol in children with and without history of wheezing. J Clin Invest. 1997; 100(12): 3184-3188.MartinezFDGravesPEBaldiniMSolomonSEricksonRAssociation between polymorphisms of ADRB2 and response to albuterol in children with and without history of wheezingJ Clin Invest1997100123184–318810.1172/JCI1198745085329399966Search in Google Scholar
Cho SH, Oh SY, Bahn JW, Choi JY, Chang YS, Kim YK, et al. Association between bronchodilating response to SABA and non-synonymous SNP of ADRB2 gene. Clin Exp Allergy. 2005; 35(9): 1162-1167.ChoSHOhSYBahnJWChoiJYChangYSKimYKAssociation between bronchodilating response to SABA and non-synonymous SNP of ADRB2 geneClin Exp Allergy20053591162–116710.1111/j.1365-2222.2005.02319.x16164442Search in Google Scholar
Salah K, Morsy S, Atta A. Effects of ADRB2 polymorphism on asthma severity and response to salbutamol on Egyptian children. Egypt J Pediatr Allergy Immunol. 2012; 10(2): 81-86.SalahKMorsySAttaAEffects of ADRB2 polymorphism on asthma severity and response to salbutamol on Egyptian childrenEgypt J Pediatr Allergy Immunol201210281–86Search in Google Scholar
Carroll CL, Stoltz P, Schramm CM, Zucker AR. ADRB2 polymorphisms affect response to treatment in children with severe asthma exacerbations. Chest. 2009; 135(5): 1186-1192.CarrollCLStoltzPSchrammCMZuckerARADRB2 polymorphisms affect response to treatment in children with severe asthma exacerbationsChest200913551186–119210.1378/chest.08-204119029431Search in Google Scholar
Choudhry S, Ung N, Avila PC, Ziv E, Nazario S, Casal J. Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. Am J Respir Crit Care Med. 2005; 171(6): 563-570.ChoudhrySUngNAvilaPCZivENazarioSCasalJPharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthmaAm J Respir Crit Care Med20051716563–57010.1164/rccm.200409-1286OC15557128Search in Google Scholar
Szczepankiewicz A, Breborowicz A, Sobkowiak P, Kramer L, Popiel A. Role of ADRB2 gene polymorphism in asthma and response to β2-agonists in Polish children. J Appl Genet. 2009; 50(3): 275-281.SzczepankiewiczABreborowiczASobkowiakPKramerLPopielARole of ADRB2 gene polymorphism in asthma and response to β2-agonists in Polish childrenJ Appl Genet2009503275–28110.1007/BF0319568319638684Search in Google Scholar
Isaza C, Sepúlveda-Arias JC, Agudelo BI, Arciniegas W, Henao J, Porras GL, et al. ADRB2 polymorphisms in asthmatic and non-asthmatic school children from Colombia and their relationship to treatment response. Pediatr Pulmonol. 2012; 47(9): 848-855.IsazaCSepúlveda-AriasJCAgudeloBIArciniegasWHenaoJPorrasGLADRB2 polymorphisms in asthmatic and non-asthmatic school children from Colombia and their relationship to treatment responsePediatr Pulmonol2012479848–85510.1002/ppul.2252122328447Search in Google Scholar
Turner S, Francis B, Vijverberg S, Pino-Yanes M, Maitland-van der Zee AH, Basu K, et al. Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: A meta-analysis stratified by treatment. J Allergy Clin Immunol. 2016; 138(1): 107-113.TurnerSFrancisBVijverbergSPino-YanesMMaitland-vander Zee AHBasuKChildhood asthma exacerbations and the Arg16 β2-receptor polymorphism: A meta-analysis stratified by treatmentJ Allergy Clin Immunol20161381107–11310.1016/j.jaci.2015.10.045493196926774659Search in Google Scholar
