Otwarty dostęp

Antidepressant effects of an inverse agonist selective for α5 GABA-A receptors in the rat forced swim test


Zacytuj

1. Olsen RW, Sieghart W: International Union of Pharmacology. LXX. Subtypes of gammaaminobutyric acid (A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update. Pharmacol Rev 2008, 60:243-260.10.1124/pr.108.00505Search in Google Scholar

2. Korpi ER, Grunder G, Luddens H: Drug interactions at GABA(A) receptors. Prog Neurobiol 2002, 67:113-159.10.1016/S0301-0082(02)00013-8Search in Google Scholar

3. Chebib M, Johnston GA: GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology. J Med Chem 2000, 43:1427-1447.10.1021/jm9904349Search in Google Scholar

4. Chapouthier G, Venault P: GABA-A receptor complex and memory processes. Curr Top Med Chem 2002, 2:841-851.10.2174/1568026023393552Search in Google Scholar

5. Krazem A, Borde N, Béracochéa D: Effects of diazepam and beta-CCM on working memory in mice: relationships with emotional reactivity. Pharmacol Biochem Behav 2001, 68:235-244.10.1016/S0091-3057(00)00444-5Search in Google Scholar

6. Rudolph U, Möhler H: Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics. Annu Rev Pharmacol Toxicol 2004, 44:475-98.10.1146/annurev.pharmtox.44.101802.121429Search in Google Scholar

7. Sieghart W, Ernst M: Heterogeneity of GABAA receptors: reviwed interest in the development of subtype-selective drugs. Curr Med Chem Cent Nerv Syst Agents 2005, 5:217-242.10.2174/1568015054863837Search in Google Scholar

8. Izquierdo I, Medina JH: Memory formation: the sequence of biochemical events in the hippocampus and its connection to activity in other brain structures. Neurobiol Learn Mem 1997, 68:285-316.10.1006/nlme.1997.3799Search in Google Scholar

9. Pirker P, Pirker S, Schwarzer C, Wieselthaler A, Sieghart W, Sperk G: GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain, Neuroscience 2000, 101:815-850.10.1016/S0306-4522(00)00442-5Search in Google Scholar

10. Sieghart W, Sperk G: Subunit composition, distribution and function of GABAA receptor subtypes. Curr Top Med Chem 2002, 2:795-816.10.2174/1568026023393507Search in Google Scholar

11. Atack JR, Pike A, Clarke A, Cook SM, Sohal B, McKernan RM, Dawson GR: Rat pharmacokinetics and pharmacodynamics of a sustained release formulation of the GABAA alpha5-selective compound L-655,708. Drug Metab Dispos 2006, 34:887-893.10.1124/dmd.105.006973Search in Google Scholar

12. Chambers MS, Atack JR, Broughton HB, Collinson N, Cook S, Dawson GR, Hobbs SC, Marshall G, Maubach KA, Pillai GV, Reeve AJ, MacLeod AM: Identifi cation of a novel, selective GABA(A) alpha5 receptor inverse agonist which enhances cognition. J Med Chem 2003, 46:2227-2240.10.1021/jm020582qSearch in Google Scholar

13. Collinson N, Atack JR, Laughton P, Dawson GR, Stephens DN: An inverse agonist selective for alpha5 subunit-containing GABAA receptors improves encoding and recall but not consolidation in the Morris water maze. Psychopharmacology 2006, 188:619-628.10.1007/s00213-006-0361-zSearch in Google Scholar

14. Dawson GR, Maubach KA, Collinson N, Cobain M, Everitt BJ, MacLeod AM, Choudhury HI, McDonald LM, Pillai G, Rycroft W, Smith AJ, Sternfeld F, Tattersall FD, Wafford KA, Reynolds DS, Seabrook GR, Atack JR: An inverse agonist selective for alpha5 subunitcontaining GABAA receptors enhances cognition. J Pharmacol Exp Ther 2006, 316:1335-1345.10.1124/jpet.105.092320Search in Google Scholar

15. Redrobe JP, Elster L, Frederiksen K, Bundgaard C, de Jong IE, Smith GP, Bruun AT, Larsen PH, Didriksen M: Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive defi cits in rats. Psychopharmacology 2012, 221:451-468.10.1007/s00213-011-2593-9Search in Google Scholar

16. Porsolt RD, Anton G, Blavet N, Jalfre M: Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur J Pharmacol 1978, 47:379-391.10.1016/0014-2999(78)90118-8Search in Google Scholar

17. Hines RM, Davies PA, Moss SJ, Maguire J: Functional regulation of GABA(A) receptors in nervous system pathologies. Curr Opin Neurobiol 2012, 22:552-558.10.1016/j.conb.2011.10.007Search in Google Scholar

18. Kalueff AV, Nutt DJ: Role of GABA in anxiety and depression. Depress Anxiety 2007, 24:495-517.10.1002/da.20262Search in Google Scholar

19. Luscher B, Fuchs T, Kilpatrick CL: GABAA receptor traffi cking-mediated plasticity of inhibitory synapses. Neuron 2011, 70:385-409.10.1016/j.neuron.2011.03.024Search in Google Scholar

20. Earnheart JC, Schweizer C, Crestani F, Iwasato T, Itohara S, Mohler H, Lüscher B: GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states. J Neurosci 2007, 27:3845-3854.10.1523/JNEUROSCI.3609-06.2007Search in Google Scholar

21. Shen Q, Lal R, Luellen BA, Earnheart JC, Andrews AM, Luscher B: Gamma-Aminobutyric acid-type A receptor defi cits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression. Biol Psychiatry 2010, 68:512-520.10.1016/j.biopsych.2010.04.024Search in Google Scholar

22. Xing B, Zhao Y, Zhang H, Dang Y, Chen T, Huang J, Luo Q: Microinjection of valproic acid into the ventrolateral orbital cortex exerts an antidepressant-like effect in the rat forced swim test. Brain Res Bull 2011, 85:153-157.10.1016/j.brainresbull.2011.03.007Search in Google Scholar

23. Crestani F, Keist R, Fritschy JM, Benke D, Vogt K, Prut L, Blüthmann H, Möhler H, Rudolph U: Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors. Proc Natl Acad Sci USA 2002, 99:8980-8985.10.1073/pnas.142288699Search in Google Scholar

24. Yee BK, Hauser J, Dolgov VV, Keist R, Möhler H, Rudolph U, Feldon J: GABA receptors containing the alpha5 subunit mediate the trace effect in aversive and appetitive conditioning and extinction of conditioned fear. Eur J Neurosci 2004, 20:1928-1936.10.1111/j.1460-9568.2004.03642.xSearch in Google Scholar

25. Braudeau J, Delatour B, Duchon A, Pereira PL, Dauphinot L, de Chaumont F, Olivo- Marin JC, Dodd RH, Hérault Y, Potier MC: Specifi c targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive defi cits in Down syndrome mice. J Psychopharmacol 2011, 25:1030-1042.10.1177/0269881111405366Search in Google Scholar

26. Elizalde N, Gil-Bea FJ, Ramírez MJ, Aisa B, Lasheras B, Del Rio J, Tordera RM: Longlasting behavioral effects and recognition memory defi cit induced by chronic mild stress in mice: Effect of antidepressant treatment. Psychopharmacology (Berl) 2008, 199:1-14.10.1007/s00213-007-1035-1Search in Google Scholar

27. Bondi CO, Jett JD, Morilak DA: Benefi cial effects of desipramine on cognitive function of chronically stressed rats are mediated by alpha1-adrenergic receptors in medial prefrontal cortex. Prog Neuropsychopharmacol Biol Psychiatry 2010, 34:913-923.10.1016/j.pnpbp.2010.04.016Search in Google Scholar

28. Samardžić J, Štrac DŠ, Obradović M, Oprić D, Obradović DI: DMCM, a benzodiazepine site inverse agonist, improves active avoidance and motivation in the rat, Behav Brain Res 2012, 235:195-199.10.1016/j.bbr.2012.07.032Search in Google Scholar

29. Vollenweider I, Smith KS, Keist R, Rudolph U: Antidepressant-like properties of α2- containing GABAA receptors. Behav Brain Res 2011, 217:77-80.10.1016/j.bbr.2010.10.009Search in Google Scholar

30. Löw K, Crestani F, Keist R, Benke D, Brünig I, Benson JA, Fritschy JM, Rülicke T, Bluethmann H, Möhler H, Rudolph U: Molecular and neuronal substrate for the selective attenuation of anxiety. Science 2000, 290:131-134.10.1126/science.290.5489.131Search in Google Scholar

31. Autry AE, Adachi M, Nosyreva E, Na ES, Los MF, Cheng PF, Kavalali ET, Monteggia LM: NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses. Nature 2011, 475:91-95.10.1038/nature10130Search in Google Scholar

32. Berman RM, Cappiello A, Anand A, Oren DA, Heninger GR, Charney DS, Krystal JH: Antidepressant effects of ketamine in depressed patients. Biol Psychiatry 2000, 47:351-354.10.1016/S0006-3223(99)00230-9Search in Google Scholar

33. Li N, Lee B, Liu RJ, Banasr M, Dwyer JM, Iwata M, Li XY, Aghajanian G, Duman RS: mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science 2010, 329:959-964.10.1126/science.1190287Search in Google Scholar

34. Krystal JH, Sanacora G, Blumberg H, Anand A, Charney DS, Marek G, Epperson CN, Goddard A, Mason GF: Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments. Mol Psychiatry 2002, 7:S71-S80. 10.1038/sj.mp.4001021Search in Google Scholar

eISSN:
1820-7448
Język:
Angielski
Częstotliwość wydawania:
4 razy w roku
Dziedziny czasopisma:
Medicine, Veterinary Medicine