<abstract xmlns="http://www.w3.org/1999/xhtml">New organotin (IV) complexes with NaL1 (sodium salt of 2-[[4-(3-methoxy-propoxy) 3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide) and NaL2 (sodium salt of 3- aminomethyl-5-methylhexanoic acid) were synthesized by the reaction of diorganotin (IV) and triorganotin (IV) salt (Bu3SnCl, Ph3SnCl, Bu2SnCl2, Me2SnCl2) using the solvent (dry toluene) by constant stirring and refluxing. All the organotin (IV) complexes were characterized by different diagnostic techniques such as FT-IR (Infra-red) and UV-visible spectroscopy. The results exhibited that ligand NaL1 (sodium salt) is attached to tin metal by a nitrogen atom of benzimidazole ring and the oxygen atom of the sulfonyl group. While ligand NaL2 (sodium salt) coordinate with tin(IV) moiety through oxygen atom of the carboxylate group. The newly synthesized complexes 1 &amp; 2 of ligand NaL1 (sodium salt) showed trigonal bipyramidal geometry while complexes 3 &amp; 4 octahedral geometry around tin(IV) centre. The organotin(IV) complexes 5-7 of ligand NaL2 (sodium salt) have the tetrahedral geometry around tin(IV) centre. The synthesized complexes (1-7) were tested for antifungal and antibacterial microbial activities. All the complexes showed significant antibacterial and anti-fungal activities against tested bacterial and fungal strains.</abstract>

New organotin (IV) complexes with NaL1 (sodium salt of 2-[[4-(3-methoxy-propoxy) 3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide) and NaL2 (sodium salt of 3- aminomethyl-5-methylhexanoic acid) were synthesized by the reaction of diorganotin (IV) and triorganotin (IV) salt (Bu3SnCl, Ph3SnCl, Bu2SnCl2, Me2SnCl2) using the solvent (dry toluene) by constant stirring and refluxing. All the organotin (IV) complexes were characterized by different diagnostic techniques such as FT-IR (Infra-red) and UV-visible spectroscopy. The results exhibited that ligand NaL1 (sodium salt) is attached to tin metal by a nitrogen atom of benzimidazole ring and the oxygen atom of the sulfonyl group. While ligand NaL2 (sodium salt) coordinate with tin(IV) moiety through oxygen atom of the carboxylate group. The newly synthesized complexes 1 & 2 of ligand NaL1 (sodium salt) showed trigonal bipyramidal geometry while complexes 3 & 4 octahedral geometry around tin(IV) centre. The organotin(IV) complexes 5-7 of ligand NaL2 (sodium salt) have the tetrahedral geometry around tin(IV) centre. The synthesized complexes (1-7) were tested for antifungal and antibacterial microbial activities. All the complexes showed significant antibacterial and anti-fungal activities against tested bacterial and fungal strains.

Organotin (IV) based Rabeprazole and Pregabalin Complexes Formation and Biocidal Investigation

Acta Chemica Malaysia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

New organotin (IV) complexes with NaL1 (sodium salt of 2-[[4-(3-methoxy-propoxy) 3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide) and NaL2 (sodium salt...

Organotin (IV) based Rabeprazole and Pregabalin Complexes Formation and Biocidal Investigation

Data publikacji: 29 cze 2020

Zakres stron: 17 - 23

DOI: https://doi.org/10.2478/acmy-2020-0003

Słowa kluczowe
Organotin carboxylate, Organotin benzimidazole, antibacterial activity, antifungal activity

© 2020 Muhammad Tariq et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Organotin (IV) based Rabeprazole and Pregabalin Complexes Formation and Biocidal Investigation

Data publikacji: 29 cze 2020

Zakres stron: 17 - 23

DOI: https://doi.org/10.2478/acmy-2020-0003

Słowa kluczoweOrganotin carboxylate, Organotin benzimidazole, antibacterial activity, antifungal activity

© 2020 Muhammad Tariq et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Słowa kluczowe
Organotin carboxylate, Organotin benzimidazole, antibacterial activity, antifungal activity