IM botulinum toxin-A improves ambulation in severe haemophilia and cerebral palsy

Introduction: The use of BtA in spasticity management is well documented in the literature for the management of hypertonicity in children with cerebral palsy. Methods: We report a case of a 2-year-old boy with severe haemophilia and cerebral palsy who received intramuscular injections of botulinum toxin-A (BtA) to reduce his spastic diplegia lower limb hypertonicity. Results: Following treatment, clinical and formal assessments demonstrated positive changes in ambulation, tolerance of orthotics, functional abilities and musculoskeletal range of movement and no adverse bleeding side effects. Conclusion: The use of BtA should be considered for the management of hypertonicity in children with haemophilia and cerebral palsy.