<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Blood vessels diseases such as cardiac infarction with coronary artery occlusion, peripheral arterial disorders, or stroke of carotid or cerebral arteries, are the leading causes of death in the world. One of medical procedures for clinical treatment of vascular diseases is the blood vessels grafting. As the autologous blood vessels, which are the “golden standard” for coronary grafting, are not always suitable for blood vessels grafting, there is a need to develop artificial blood vessels as a vascular prostheses, either from natural and synthetic materials, permanent synthetic or biodegradable scaffolds which would be suitable for vascular grafts. Considering this to be our study goal we made bilayered biodegradable polycaprolactone scaffolds with different properties and evaluated their morphological and biomechanical characteristics.</p></abstract>

Blood vessels diseases such as cardiac infarction with coronary artery occlusion, peripheral arterial disorders, or stroke of carotid or cerebral arteries, are the leading causes of death in the world. One of medical procedures for clinical treatment of vascular diseases is the blood vessels grafting. As the autologous blood vessels, which are the “golden standard” for coronary grafting, are not always suitable for blood vessels grafting, there is a need to develop artificial blood vessels as a vascular prostheses, either from natural and synthetic materials, permanent synthetic or biodegradable scaffolds which would be suitable for vascular grafts. Considering this to be our study goal we made bilayered biodegradable polycaprolactone scaffolds with different properties and evaluated their morphological and biomechanical characteristics.

Manufacturing of Biodegradable Scaffolds to Engineer Artificial Blood Vessel

Department of Physiology, Faculty of Medical Sciences

Bioengineering Research and Development Center (BioIRC)

Experimental and Applied Biomedical Research (EABR)

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Manufacturing of Biodegradable Scaffolds to Engineer Artificial Blood Vessel"}

Blood vessels diseases such as cardiac infarction with coronary artery occlusion, peripheral arterial disorders, or stroke of carotid or cerebral arteries, are...

Manufacturing of Biodegradable Scaffolds to Engineer Artificial Blood Vessel

Pubblicato online: 29 ott 2018

Pagine: 215 - 221

Ricevuto: 06 mar 2017

Accettato: 27 mar 2017

DOI: https://doi.org/10.1515/sjecr-2017-0032

Parole chiave
blood vessel, vascular grafts, biodegradable scaffolds, electrospinning

© 2018 Maja Milosevic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Manufacturing of Biodegradable Scaffolds to Engineer Artificial Blood Vessel

Pubblicato online: 29 ott 2018

Pagine: 215 - 221

Ricevuto: 06 mar 2017

Accettato: 27 mar 2017

DOI: https://doi.org/10.1515/sjecr-2017-0032

Parole chiaveblood vessel, vascular grafts, biodegradable scaffolds, electrospinning

© 2018 Maja Milosevic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
blood vessel, vascular grafts, biodegradable scaffolds, electrospinning