<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Morganella morganii (M. morganii) is a Gram-negative aerobic and facultative anaerobic rod, belonging to the Enterobacteriaceae family. This pathogen is uncommon in community-acquired infections, most often being found in postoperative nosocomial and urinary tract infections. Infection of the central nervous system with this pathogen is rare. We present the case of a 66-year-old patient who underwent colon cancer surgery, chemotherapy and radiotherapy, had left iliac anus, type 2 diabetes and developed acute meningoencephalitis caused by M. morganii. Cerebrospinal fluid examination revealed increased number of polymorphonuclear neutrophils, modified biochemistry and AmpC beta-lactamase producing M. morganii strain. After initiation of antibiotic treatment, initially with empirical therapy represented by meropenem and vancomycin, afterwards adjusted to meropenem and ciprofloxacin, according to the stain’s susceptibility to antimicrobials the patient’s evolution was favourable, in spite of the existence of two immune suppressing conditions.</p></abstract>

Morganella morganii (M. morganii) is a Gram-negative aerobic and facultative anaerobic rod, belonging to the Enterobacteriaceae family. This pathogen is uncommon in community-acquired infections, most often being found in postoperative nosocomial and urinary tract infections. Infection of the central nervous system with this pathogen is rare. We present the case of a 66-year-old patient who underwent colon cancer surgery, chemotherapy and radiotherapy, had left iliac anus, type 2 diabetes and developed acute meningoencephalitis caused by M. morganii. Cerebrospinal fluid examination revealed increased number of polymorphonuclear neutrophils, modified biochemistry and AmpC beta-lactamase producing M. morganii strain. After initiation of antibiotic treatment, initially with empirical therapy represented by meropenem and vancomycin, afterwards adjusted to meropenem and ciprofloxacin, according to the stain’s susceptibility to antimicrobials the patient’s evolution was favourable, in spite of the existence of two immune suppressing conditions.

Acute community-acquired meningoencephalitis with Morganella morganii – a case report / Meningoencefalită acută comunitară cu Morganella morganii – prezentare de caz

Infectious Diseases, Department M4, Clinical Sciences, Faculty of Medicine, University of Medicine and Pharmacy Tirgu Mures, Romania

Microbiology, Department M2, Functional and Additional Sciences, Faculty of Medicine, University of Medicine and Pharmacy Tirgu Mures, Romania

Family Medicine, Department M3, Clinical Sciences and Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy Tirgu Mures, Romania

Revista Romana de Medicina de Laborator

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Morganella morganii (M. morganii) is a Gram-negative aerobic and facultative anaerobic rod, belonging to the Enterobacteriaceae family. This pathogen is...

Acute community-acquired meningoencephalitis with Morganella morganii – a case report / Meningoencefalită acută comunitară cu Morganella morganii – prezentare de caz

Pubblicato online: 30 set 2015

Pagine: 333 - 340

Ricevuto: 15 apr 2015

Accettato: 08 ago 2015

DOI: https://doi.org/10.1515/rrlm-2015-0031

Parole chiave
meningoencephalitis, M. morganii, immunosuppression, antibiotic therapy

© by Brindusa Tilea

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Acute community-acquired meningoencephalitis with Morganella morganii – a case report / Meningoencefalită acută comunitară cu Morganella morganii – prezentare de caz

Pubblicato online: 30 set 2015

Pagine: 333 - 340

Ricevuto: 15 apr 2015

Accettato: 08 ago 2015

DOI: https://doi.org/10.1515/rrlm-2015-0031

Parole chiavemeningoencephalitis, M. morganii, immunosuppression, antibiotic therapy

© by Brindusa Tilea

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
meningoencephalitis, M. morganii, immunosuppression, antibiotic therapy