<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Early onset Marfan Syndrome (eoMFS) is a rare, severe form of Marfan Syndrome (MFS). The disease has a poor prognosis and most patients present with resistance to heart failure treatment during the newborn period. This report presents two cases of eoMFS with similar clinical features diagnosed in the newborn period and who died at an early age due to the complications related to the involvement of the cardiovascular system.</p></abstract>

Early onset Marfan Syndrome (eoMFS) is a rare, severe form of Marfan Syndrome (MFS). The disease has a poor prognosis and most patients present with resistance to heart failure treatment during the newborn period. This report presents two cases of eoMFS with similar clinical features diagnosed in the newborn period and who died at an early age due to the complications related to the involvement of the cardiovascular system.

Early Onset Marfan Syndrome: Atypical Clinical Presentation of Two Cases

M.D., Division of Pediatric Cardiology, Erciyes University Faculty of Medicine, Kayseri, Turkey, 38039. Tel: +903522076666, Ext. 25036. Fax: +903524375825

Division of Pediatric Cardiology, Erciyes University Faculty of Medicine, Kayseri, Turkey

Division of Neonatology, Erciyes University Faculty of Medicine, Kayseri, Turkey

Department of Medical Genetics, Mersin Women Health and Children Hospital, Mersin, Turkey

Balkan Journal of Medical Genetics

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Early Onset Marfan Syndrome: Atypical Clinical Presentation of Two Cases"}

Early onset Marfan Syndrome (eoMFS) is a rare, severe form of Marfan Syndrome (MFS). The disease has a poor prognosis and most patients present with resistance...

Early Onset Marfan Syndrome: Atypical Clinical Presentation of Two Cases

Pubblicato online: 30 dic 2015

Pagine: 71 - 76

DOI: https://doi.org/10.1515/bjmg-2015-0008

Parole chiave
Craniosynostosis, Early onset Marfan Syndrome (eoMFS), Heart failure, Neonatal Marfan Syndrome (MFS), Pediatric, Supraventricular tachycardia

© Balkan Journal of Medical Genetics

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Early Onset Marfan Syndrome: Atypical Clinical Presentation of Two Cases

Pubblicato online: 30 dic 2015

Pagine: 71 - 76

DOI: https://doi.org/10.1515/bjmg-2015-0008

Parole chiaveCraniosynostosis, Early onset Marfan Syndrome (eoMFS), Heart failure, Neonatal Marfan Syndrome (MFS), Pediatric, Supraventricular tachycardia

© Balkan Journal of Medical Genetics

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Parole chiave
Craniosynostosis, Early onset Marfan Syndrome (eoMFS), Heart failure, Neonatal Marfan Syndrome (MFS), Pediatric, Supraventricular tachycardia