<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_1905-7415.1004.496_s_001_w2aab3b7b4b1b6b1aab1c16b1Aa"><h3>Background</h3><p>Chronic hepatitis B (HBV) and C virus (HCV) infections are important causes of morbidity and mortality in patients who undergo hemodialysis (HD).</p></sec><sec id="j_1905-7415.1004.496_s_002_w2aab3b7b4b1b6b1aab1c16b2Aa"><h3>Objectives</h3><p>To define seroprevalence of HBV and HCV in patients who underwent HD in Antalya province, Turkey.</p></sec><sec id="j_1905-7415.1004.496_s_003_w2aab3b7b4b1b6b1aab1c16b3Aa"><h3>Methods</h3><p>We included 1347 patients with end-stage renal failure who underwent HD at one of the 23 centers in Antalya province from January 01 to March 31, 2014 in this retrospective cross-sectional study. Hepatitis B surface antigen (HBsAg) and anti-HCV seropositivity were assessed clinically using a third-generation enzyme-linked immunosorbent assay. HBV DNA and HCV RNA were determined in HBsAg positive and anti- HCV positive HD patients respectively.</p></sec><sec id="j_1905-7415.1004.496_s_004_w2aab3b7b4b1b6b1aab1c16b4Aa"><h3>Results</h3><p>Of the patients included, 805 (59.8%) were male. Mean age (± standard deviation) of the patients was 53.9 ± 17.0 (range 17–89) years. The sera of 2.4% patients was positive for HBsAg, and the sera of 5.5% of the patients was positive for anti-HCV. The sera of 56% of patients positive for HBsAg was also positive for HBV DNA, and the sera of 43% of patients positive for anti-HCV was also positive for HCV RNA. Coexistence of HBsAg and anti-HCV was 1.02%.</p></sec><sec id="j_1905-7415.1004.496_s_005_w2aab3b7b4b1b6b1aab1c16b5Aa"><h3>Conclusions</h3><p>The present study showed that the prevalence of chronic HBV and HCV infection in patients who underwent HD in Antalya province was moderate-to-low for Turkey. Compliance of HD centers with infection control rules, isolation of HBsAg positive patients, isolation of the equipment used for HBV susceptible patients, and active surveillance of the HD patients may have resulted in lower prevalence rates.</p></sec></abstract>

BackgroundChronic hepatitis B (HBV) and C virus (HCV) infections are important causes of morbidity and mortality in patients who undergo hemodialysis (HD).ObjectivesTo define seroprevalence of HBV and HCV in patients who underwent HD in Antalya province, Turkey.MethodsWe included 1347 patients with end-stage renal failure who underwent HD at one of the 23 centers in Antalya province from January 01 to March 31, 2014 in this retrospective cross-sectional study. Hepatitis B surface antigen (HBsAg) and anti-HCV seropositivity were assessed clinically using a third-generation enzyme-linked immunosorbent assay. HBV DNA and HCV RNA were determined in HBsAg positive and anti- HCV positive HD patients respectively.ResultsOf the patients included, 805 (59.8%) were male. Mean age (± standard deviation) of the patients was 53.9 ± 17.0 (range 17–89) years. The sera of 2.4% patients was positive for HBsAg, and the sera of 5.5% of the patients was positive for anti-HCV. The sera of 56% of patients positive for HBsAg was also positive for HBV DNA, and the sera of 43% of patients positive for anti-HCV was also positive for HCV RNA. Coexistence of HBsAg and anti-HCV was 1.02%.ConclusionsThe present study showed that the prevalence of chronic HBV and HCV infection in patients who underwent HD in Antalya province was moderate-to-low for Turkey. Compliance of HD centers with infection control rules, isolation of HBsAg positive patients, isolation of the equipment used for HBV susceptible patients, and active surveillance of the HD patients may have resulted in lower prevalence rates.

Seroprevalence of hepatitis B and C virus in patients who undergo hemodialysis in Antalya province, Turkey

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

BackgroundChronic hepatitis B (HBV) and C virus (HCV) infections are important causes of morbidity and mortality in patients who undergo hemodialysis...

	HBsAg positive n = 32	Anti-HCV positive n = 74
Mean age (year+ SD)	57.1+11.79	53.5 + 9.89
Sex, n (%)
Male	14 (44%)	42 (57%)
Female	18 (56%)	32 (43%)
Dialysis Duration n (%)
<5 years	12 (38%)	45 (61%)
≥5 years	20 (62%)	29 (39%)
Blood transfusion n (%)
Yes	18 (56%)	30 (41%)
No	14 (44%)	44 (59%)

Seroprevalence of hepatitis B and C virus in patients who undergo hemodialysis in Antalya province, Turkey

Article Category: Brief communication (Original)

Publié en ligne: 31 janv. 2017

Pages: 339 - 344

DOI: https://doi.org/10.5372/1905-7415.1004.496

Mots clés
HBsAg, HBV, HCV, hemodialysis, seroprevalence

© 2016 Filiz Kizilates, Hande Berk, Melahat Coban, Derya Seyman, Metin Sarikaya, Funda Sari, Nefise Oztoprak

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Demographic characteristics of patients positive for HBsAg and anti-HCV

Seroprevalence of hepatitis B and C virus in patients who undergo hemodialysis in Antalya province, Turkey

Article Category: Brief communication (Original)

Publié en ligne: 31 janv. 2017

Pages: 339 - 344

DOI: https://doi.org/10.5372/1905-7415.1004.496

Mots clésHBsAg, HBV, HCV, hemodialysis, seroprevalence

© 2016 Filiz Kizilates, Hande Berk, Melahat Coban, Derya Seyman, Metin Sarikaya, Funda Sari, Nefise Oztoprak

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Demographic characteristics of patients positive for HBsAg and anti-HCV

Mots clés
HBsAg, HBV, HCV, hemodialysis, seroprevalence