<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml">The Preyssler, Wells-Dowson and Keggin heteropolyacids are efficient and eco-friendly solid acid catalysts for the acylation of electron-rich aromatic compounds with acid anhydrides. The performance of different forms of heteropolyacids was compared. In all the cases, the best results were obtained using the Preyssler heteropolyacid as the catalyst. In the presence of 25 mol% (with respect to H+ equivalency) Preyssler catalyst, highly <italic>para</italic>-selective acetylation of anisole occurs using two equivalents of acetic anhydride, in 15 min at room temperature. The isolated yield of the <italic>p</italic>-methoxyacetophenone product is 98%.</abstract>

The Preyssler, Wells-Dowson and Keggin heteropolyacids are efficient and eco-friendly solid acid catalysts for the acylation of electron-rich aromatic compounds with acid anhydrides. The performance of different forms of heteropolyacids was compared. In all the cases, the best results were obtained using the Preyssler heteropolyacid as the catalyst. In the presence of 25 mol% (with respect to H+ equivalency) Preyssler catalyst, highly para-selective acetylation of anisole occurs using two equivalents of acetic anhydride, in 15 min at room temperature. The isolated yield of the p-methoxyacetophenone product is 98%.

Acylation of aromatic compounds by acid anhydrides using Preyssler's anion [NaP5W30O110]14- and heteropolyacids as green catalysts

Department of Chemistry, Islamic Azad University, Mashhad, IRAN

Agricultural Researches and Services Center, Mashhad, IRAN

Cluster for Molecular Chemistry, Department of Organic Chemistry, Radboud University Nijmegen, The Netherlands

Polish Journal of Chemical Technology

Acylation of aromatic compounds by acid anhydrides using Preyssler's anion [NaPWO] and heteropolyacids as green catalysts

The Preyssler, Wells-Dowson and Keggin heteropolyacids are efficient and eco-friendly solid acid catalysts for the acylation of electron-rich aromatic...

Acylation of aromatic compounds by acid anhydrides using Preyssler's anion [NaP₅W₃₀O₁₁₀]^14- and heteropolyacids as green catalysts

Publié en ligne: 16 juin 2011

Pages: 11 - 17

DOI: https://doi.org/10.2478/v10026-011-0017-6

Mots clés
Acylation, Preyssler, Anhydride, Heteropolyacids, Catalyst, Aromatic compounds

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