Risk for stroke and chronic kidney disease in patients with sleep apnea syndrome and heart failure with different ejection fractions
, , , et | 02 juil. 2019
À propos de cet article
Article Category: Original Papers
Publié en ligne: 02 juil. 2019
Pages: 15 - 20
DOI: https://doi.org/10.2478/pneum-2019-0002
Mots clés
© 2019 Ardelean et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Laboratory parameter values in groups with HFrEF and HFpEF and p value.
| HFrEF | HFpEF | ||
|---|---|---|---|
| Laboratory parameters | Mean value±standard deviation | Mean value±standard deviation | |
| ESR (mg/dl) | 21.5±24.3 | 14.4±9 | 0.21 |
| Uric acid (mg/dl) | 7.4±2.8 | 6.6±1.8 | 0.36 |
| Creatinine (mg/dl) | 0.049 | ||
| Erythrocyte count (*106/ml) | 4.9±0.9 | 4.8±0.5 | 0.8 |
| Cholesterol (mg/dl) | 164.7±38.4 | 164.7±54.2 | 0.9 |
| LDL-cholesterol (mg/dl) | 94.1±29 | 79.1±25.3 | 0.15 |
| HDL-cholesterol (mg/dl) | 42.4±10.7 | 41.9±10.4 | 0.88 |
| Triglycerides (mg/dl) | 133.5±81.6 | 191.4±105.6 | 0.06 |
The number of patients with valvular pathology in the groups with HFrEF and HFpEF and p value.
| Valve alteration | HFrEF (n, %) | HFpEF (n, %) | |||
|---|---|---|---|---|---|
| Mitral insufficiency | 24 patients | 96% | 21 patients | 80.7% | |
| Aortic insufficiency | |||||
| Tricuspid insufficiency | |||||
| Pulmonary insufficiency | 1 patient | 4% | 3 patients | 11.5% | |
The number of patients with different comorbidities in the groups with HFrEF and HFpEF and p value.
| Comorbidities | HFrEF (n, %) | HFpEF (n, %) | |||
|---|---|---|---|---|---|
| COPD | 8 patients | 32% | 3 patients | 11.5% | 0.07 |
| Diabetes | 7 patients | 28% | 14 patients | 53.8% | 0.06 |
| Dyslipidemia | 15 patients | 60% | 18 patients | 69.2% | 0.5 |
| Coronary artery disease | 20 patients | 80% | 18 patients | 69.2% | 0.38 |
| Arrhythmias | 18 patients | 72% | 13 patients | 50% | 0.11 |
| Stroke | 1 patient | 4% | 6 patients | 23% | 0.04 |
| Smoking status | 11 patients | 44% | 11 patients | 42.3% | 0.9 |
The values of the polygraphic parameters in the groups with HFrEF and HFpEF.
| HFrEF | HFpEF | ||
|---|---|---|---|
| Polygraphic parameters | Mean value ± standard deviation | Mean value ± standard deviation | |
| Central apnea (n/h) | 4.6±8.3 | 5.6±11.4 | 0.7 |
| Obstructive apnea (n/h) | 25.9±18.5 | 25.7±18.7 | 0.97 |
| Mixed apnea (n/h) | 4.6±7.6 | 6.2±10.7 | 0.44 |
| Desaturation index (n/h) | 44.8±27.1 | 41.2±21.2 | 0.59 |
| Mean saturation (%) | 90.2±6.3 | 89.8±5.3 | 0.84 |
| Lowest SpO2 (%) | 70.6±12.1 | 72.1±14 | 0.69 |
| Longest SpO2 <88% (min) | 3±5.8 | 10.5±33.5 | 0.29 |
| Epworth scale | 14±6 | 13.3±5.6 | 0.69 |
| SAS score | 4.6±0.8 | 4.5±0.7 | 0.71 |
Anthropometric values in the groups with HFrEF versus HFpEF.
| HFrEF (25 patients) | HFpEF (26 patients) | ||
|---|---|---|---|
| Mean value ± standard deviation | Mean value ± standard deviation | ||
| Age (years) | 63.6±8.8 | 61.54±9.1 | 0.39 |
| Gender | 7 females (28%) | 7 females (27%) | |
| 18 males (72%) | 19 males (73) | ||
| BMI (kg/m2) | 37.9±7.5 | 37±6.4 | 0.65 |
| Neck circumference (cm) | 46±4.4 | 45.4±3.6 | 0.57 |
| Abdominal circumference (cm) | 127.2±13.9 | 126.6±12.9 | 0.87 |