<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml">In recent years, the town of Settat has seen a considerable industrial growth, which has resulted in increased environmental pollution. This includes pollution by household and industrial wastewaters, which are released into the Boumoussa River without any preliminary treatment. The river valley crosses the community of Mzamza 8 km to the north of the town. Years of drought forced members of the community to use this polluted ground water for irrigation and put themselves and the environment at risk.The aim of this study was to determine the physicochemical and metal profile of Settat wastewaters and to assess their impact on the water table. The second objective was to investigate the genotoxic potential of wastewater on human peripheral blood lymphocytes <italic>in vitro</italic>, using the micronucleus test and cellular proliferation index.This study demonstrated significant pollution of Boumoussa valley groundwater and of the local wells. Sampled water induced a clear increase in the frequency of micronucleated cells and a lower cell proliferation in human peripheral blood lymphocytes <italic>in vitro.</italic></abstract>

In recent years, the town of Settat has seen a considerable industrial growth, which has resulted in increased environmental pollution. This includes pollution by household and industrial wastewaters, which are released into the Boumoussa River without any preliminary treatment. The river valley crosses the community of Mzamza 8 km to the north of the town. Years of drought forced members of the community to use this polluted ground water for irrigation and put themselves and the environment at risk.The aim of this study was to determine the physicochemical and metal profile of Settat wastewaters and to assess their impact on the water table. The second objective was to investigate the genotoxic potential of wastewater on human peripheral blood lymphocytes in vitro, using the micronucleus test and cellular proliferation index.This study demonstrated significant pollution of Boumoussa valley groundwater and of the local wells. Sampled water induced a clear increase in the frequency of micronucleated cells and a lower cell proliferation in human peripheral blood lymphocytes in vitro.

<italic>In Vitro</italic> Genotoxicity of Wastewaters from the Town of Settat, Morocco

Laboratory of Environmental Metrology, University Hassan I, FST Settat, Morocco

Research Group on Toxicogenetics and Mutagenesis, Laboratory of Agrofood and Health, University Hassan I, FST Settat, Morocco

Laboratory of Applied Geology, University Hassan I, FST Settat, Morocco

Department of Epidemiology and Toxicology, Scientific Institute of Public Health, Brussels, Belgium

Archives of Industrial Hygiene and Toxicology

 Genotoxicity of Wastewaters from the Town of Settat, Morocco

In recent years, the town of Settat has seen a considerable industrial growth, which has resulted in increased environmental pollution. This includes pollution...

In Vitro Genotoxicity of Wastewaters from the Town of Settat, Morocco

Publié en ligne: 29 sept. 2009

Pages: 289 - 296

DOI: https://doi.org/10.2478/10004-1254-60-2009-1926

Mots clés
Boumoussa, fizikalno-kemijska karakterizacija, mikronukleus, proliferacijski indeks, teški metali

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