How polymorphisms of the cytochrome P450 genes affect ibuprofen and diclofenac metabolism and toxicity / Kako polimorfizmi gena citokroma P450 utječu na metabolizam i toksičnost ibuprofena i diklofenaka

Publié en ligne: 15 avr. 2016

Pages: 1 - 8

Reçu: 01 déc. 2015

Accepté: 01 mars 2016

DOI: https://doi.org/10.1515/aiht-2016-67-2754

Mots clés

adverse effects, allelic variants, CYP2C8, CYP2C9, drug metabolism, gastrointestinal bleeding, genotyping, hepatotoxicity, pharmacogenetics, pharmacogenomics, pharmacokinetics

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