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Asian Biomedicine
Édition 14 (2020): Edition 5 (October 2020)
Accès libre
Nuclear protein in testis midline carcinoma in a Turkish boy: a case report
Büşra Yaprak Bayrak
Büşra Yaprak Bayrak
,
Demir Kürşat Yildiz
Demir Kürşat Yildiz
,
Uğur Demirsoy
Uğur Demirsoy
,
Funda Çorapçioğlu
Funda Çorapçioğlu
,
Yonca Anik
Yonca Anik
et
Christopher A. French
Christopher A. French
| 31 oct. 2020
Asian Biomedicine
Édition 14 (2020): Edition 5 (October 2020)
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Article Category:
Clinical report
Publié en ligne:
31 oct. 2020
Pages:
203 - 208
DOI:
https://doi.org/10.1515/abm-2020-0029
Mots clés
carcinoma
,
immunohistochemistry
,
in situ hybridization, fluorescence
,
nuclear protein in testis, human
,
Turkey
© 2020 Büşra Yaprak Bayrak et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Figure 1
Histopathology of an abdominal lymph node derived from the patient with nuclear protein in testis (NUT) midline carcinoma. Undifferentiated tumor cells infiltrating into the lymph node are prominent. Hematoxylin and eosin staining. (A) 100× (scale bar 100 μm); (B) 100× (scale bar 100 μm); and (C) 400× (scale bar 25 μm).
Figure 2
Micrograph images of an abdominal lymph node section immunohistochemistry derived from the patient with nuclear protein in testis (NUT) midline carcinoma. Immunoreactivity is indicated by the dark-brown staining from oxidized diaminobenzidine chromogen used in the method. The blue counterstain is Mayer's hematoxylin. A. Positive cytoplasmic immunoreactivity for cytokeratin (AE1/AE3), 200× (scale bar 50 μm). B. Positive cytoplasmic immunoreactivity for epithelial membrane antigen, 200× (scale bar 50 μm).
Figure 3
Positive nuclear immunoreactivity for nuclear protein in testis (NUT) in an abdominal lymph node derived from the patient with NUT midline carcinoma is indicated by the dark-brown staining of tumoral nuclei from oxidized diaminobenzidine chromogen used in the method. The blue counterstain is Meyer‘s hematoxylin, which stained nontumoral nuclei dark blue. Some cytoplasmic staining is also seen in lighter blue due to the long incubation time with the hematoxylin. (A) 40× (scale bar 200 μm), (B) 100× (scale bar 50 μm), and (C) 200× (scale bar 20 μm).