<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_raon-2018-0019_s_005_w2aab2b8c69b1b7b1aab1c16b1Aa"><h3>Background</h3><p>The accuracy of dose calculation is crucial for success of the radiotherapy treatment. One of the methods that represent the current standard for patient-specific dosimetry is the evaluation of dose distributions measured with an ionization chamber array inside a homogeneous phantom using gamma method. Nevertheless, this method does not replicate the realistic conditions present when a patient is undergoing therapy. Therefore, to more accurately evaluate the treatment planning system (TPS) capabilities, gamma passing rates were examined for beams of different complexity passing through inhomogeneous phantoms.</p></sec><sec id="j_raon-2018-0019_s_006_w2aab2b8c69b1b7b1aab1c16b2Aa"><h3>Materials and methods</h3><p>The research was performed using Siemens Oncor Expression linear accelerator, Siemens Somatom Open CT simulator and Elekta Monaco TPS. A 2D detector array was used to evaluate dose distribution accuracy in homogeneous, semi-anthropomorphic and anthropomorphic phantoms. Validation was based on gamma analysis with 3%/3mm and 2%/2mm criteria, respectively.</p></sec><sec id="j_raon-2018-0019_s_007_w2aab2b8c69b1b7b1aab1c16b3Aa"><h3>Results</h3><p>Passing rates of the complex dose distributions degrade depending on the thickness of non-water equivalent material. They also depend on dose reporting mode used. It is observed that the passing rate decreases with plan complexity. Comparison of the data for all set-ups of semi-anthropomorphic and anthropomorphic phantoms shows that passing rates are higher in the anthropomorphic phantom.</p></sec><sec id="j_raon-2018-0019_s_008_w2aab2b8c69b1b7b1aab1c16b4Aa"><h3>Conclusions</h3><p>Presented results raise a question of possible limits of dose distribution verification in assessment of plan delivery quality. Consequently, good results obtained using standard patient specific dosimetry methodology do not guarantee the accuracy of delivered dose distribution in real clinical cases.</p></sec></abstract>

BackgroundThe accuracy of dose calculation is crucial for success of the radiotherapy treatment. One of the methods that represent the current standard for patient-specific dosimetry is the evaluation of dose distributions measured with an ionization chamber array inside a homogeneous phantom using gamma method. Nevertheless, this method does not replicate the realistic conditions present when a patient is undergoing therapy. Therefore, to more accurately evaluate the treatment planning system (TPS) capabilities, gamma passing rates were examined for beams of different complexity passing through inhomogeneous phantoms.Materials and methodsThe research was performed using Siemens Oncor Expression linear accelerator, Siemens Somatom Open CT simulator and Elekta Monaco TPS. A 2D detector array was used to evaluate dose distribution accuracy in homogeneous, semi-anthropomorphic and anthropomorphic phantoms. Validation was based on gamma analysis with 3%/3mm and 2%/2mm criteria, respectively.ResultsPassing rates of the complex dose distributions degrade depending on the thickness of non-water equivalent material. They also depend on dose reporting mode used. It is observed that the passing rate decreases with plan complexity. Comparison of the data for all set-ups of semi-anthropomorphic and anthropomorphic phantoms shows that passing rates are higher in the anthropomorphic phantom.ConclusionsPresented results raise a question of possible limits of dose distribution verification in assessment of plan delivery quality. Consequently, good results obtained using standard patient specific dosimetry methodology do not guarantee the accuracy of delivered dose distribution in real clinical cases.

Evaluation of two-dimensional dose distributions for pre-treatment patient-specific IMRT dosimetry

Department of Medical Physics and Biophysics

Radiology and Oncology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

BackgroundThe accuracy of dose calculation is crucial for success of the radiotherapy treatment. One of the methods that represent the current standard for...

Evaluation of two-dimensional dose distributions for pre-treatment patient-specific IMRT dosimetry

Article Category: Research Article

Publicado en línea: 30 abr 2018

Páginas: 346 - 352

Recibido: 05 dic 2017

Aceptado: 13 feb 2018

DOI: https://doi.org/10.2478/raon-2018-0019

© 2018 Đeni Smilovic Radojcic, David Rajlic, Bozidar Casar, Manda Svabic Kolacio, Nevena Obajdin, Dario Faj, Slaven Jurkovic, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.