<abstract xmlns="http://www.w3.org/1999/xhtml">The current study investigated the protective effect of Hertia cheirifolia L. n-butanol extract on oxidative stress in vitro by measuring lipid peroxidation (MDA) level and superoxide anion (O2•-) production in liver and heart mitochondria of rat. In addition, the antioxidant potential of H. cheirifolia n-butanol extract was evaluated by using five methods: ABTS•+, O2•-, Bleaching of β-carotene in linoleic acid, CUPRAC and Ferric reducing power. The results indicated that n-butanol extract contained large amounts of total phenolics (203.52±1.81 mg GAE/g) and flavonoids (104.86±0.57 mg QE/g), and had an interesting antioxidant activity and protective effect on mitochondrial oxidative stress. Therefore, H. cheirifolia n-butanol extract may serve as potential source of natural antioxidant for pharmaceutical applications.</abstract>

The current study investigated the protective effect of Hertia cheirifolia L. n-butanol extract on oxidative stress in vitro by measuring lipid peroxidation (MDA) level and superoxide anion (O2•-) production in liver and heart mitochondria of rat. In addition, the antioxidant potential of H. cheirifolia n-butanol extract was evaluated by using five methods: ABTS•+, O2•-, Bleaching of β-carotene in linoleic acid, CUPRAC and Ferric reducing power. The results indicated that n-butanol extract contained large amounts of total phenolics (203.52±1.81 mg GAE/g) and flavonoids (104.86±0.57 mg QE/g), and had an interesting antioxidant activity and protective effect on mitochondrial oxidative stress. Therefore, H. cheirifolia n-butanol extract may serve as potential source of natural antioxidant for pharmaceutical applications.

<italic>In vitro</italic> antioxidant activity and protective effect of <italic>Hertia cheirifolia</italic> L. n-butanol extract against liver and heart mitochondrial oxidative stress in rat

Department of Nature and Life Sciences, Faculty of Exact Sciences and Nature and Life Sciences

Laboratory of Animal Eco-Physiology, Department of Biology, Faculty of Sciences

Laboratory of Bio-molecules and Plant Breeding, Department of Nature and Life Sciences, Faculty of Exact Sciences

Laboratory of Molecular Toxicology, Faculty of Sciences

Acta Scientifica Naturalis

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

 antioxidant activity and protective effect of  L. n-butanol extract against liver and heart mitochondrial oxidative stress in rat

The current study investigated the protective effect of Hertia cheirifolia L. n-butanol extract on oxidative stress in vitro by measuring lipid peroxidation...

In vitro antioxidant activity and protective effect of Hertia cheirifolia L. n-butanol extract against liver and heart mitochondrial oxidative stress in rat

Publicado en línea: 18 abr 2020

Páginas: 33 - 45

DOI: https://doi.org/10.2478/asn-2020-0005

Palabras clave
L., phenolics, flavonoids, liver and heart mitochondria, antioxidant activity

© 2020 Mouna Menakh et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

In vitro antioxidant activity and protective effect of Hertia cheirifolia L. n-butanol extract against liver and heart mitochondrial oxidative stress in rat

Publicado en línea: 18 abr 2020

Páginas: 33 - 45

DOI: https://doi.org/10.2478/asn-2020-0005

Palabras claveL., phenolics, flavonoids, liver and heart mitochondria, antioxidant activity

© 2020 Mouna Menakh et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Palabras clave
L., phenolics, flavonoids, liver and heart mitochondria, antioxidant activity