<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Primary melanoma of the eyelid is a rare malignant tumour that accounts for &lt;1% of all malignant melanomas and about 1% of malignant tumours of the eyelid. The most common clinical presentation of melanoma is an oval lesion; linear presentation is uncommon. We presented a 79-year-old woman with a several-month history of a rapidly-growing, irregular, linear, pigmented cutaneous lesion on the right lower eyelid, involving the eyelid margin. The lesion measured 2 cm x 0,8 cm x 0,2 cm. Anterior and posterior segments appeared normal in both eyes, without pathological findings on ocular ultrasound examination. After excision biopsy, histopathological examination revealed a nodular melanoma. The case underwent additional investigations for staging and therapy. The current therapeutic strategies in eyelid melanoma include surgical excision, systemic chemotherapy, immunotherapy, targeted therapy or radiotherapy. Despite advanced research methods in the field, the management of eyelid melanoma is still a major challenge.</p></abstract>

Primary melanoma of the eyelid is a rare malignant tumour that accounts for <1% of all malignant melanomas and about 1% of malignant tumours of the eyelid. The most common clinical presentation of melanoma is an oval lesion; linear presentation is uncommon. We presented a 79-year-old woman with a several-month history of a rapidly-growing, irregular, linear, pigmented cutaneous lesion on the right lower eyelid, involving the eyelid margin. The lesion measured 2 cm x 0,8 cm x 0,2 cm. Anterior and posterior segments appeared normal in both eyes, without pathological findings on ocular ultrasound examination. After excision biopsy, histopathological examination revealed a nodular melanoma. The case underwent additional investigations for staging and therapy. The current therapeutic strategies in eyelid melanoma include surgical excision, systemic chemotherapy, immunotherapy, targeted therapy or radiotherapy. Despite advanced research methods in the field, the management of eyelid melanoma is still a major challenge.

A Peculiar Case of Cutaneous Eyelid Melanoma: Clinicopathological Questions and Therapeutic Challenges

“Gr. T. Popa” University of Medicine and Pharmacy

Acta Medica Transilvanica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Primary melanoma of the eyelid is a rare malignant tumour that accounts for <1% of all malignant melanomas and about 1% of malignant tumours of the eyelid. The...

A Peculiar Case of Cutaneous Eyelid Melanoma: Clinicopathological Questions and Therapeutic Challenges

Publicado en línea: 03 ago 2020

Páginas: 15 - 17

Recibido: 27 feb 2020

Aceptado: 28 may 2020

DOI: https://doi.org/10.2478/amtsb-2020-0020

Palabras clave
malignant melanoma, eyelid, cutaneous, linear

© 2020 Alin Dumitru Ciubotaru et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

A Peculiar Case of Cutaneous Eyelid Melanoma: Clinicopathological Questions and Therapeutic Challenges

Publicado en línea: 03 ago 2020

Páginas: 15 - 17

Recibido: 27 feb 2020

Aceptado: 28 may 2020

DOI: https://doi.org/10.2478/amtsb-2020-0020

Palabras clavemalignant melanoma, eyelid, cutaneous, linear

© 2020 Alin Dumitru Ciubotaru et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Palabras clave
malignant melanoma, eyelid, cutaneous, linear