Cardiac Stem Cell Therapy, Resident Progenitor Cells and the role of Cellular Signalling; a Review
, , y | 08 nov 2019
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Publicado en línea: 08 nov 2019
Páginas: 112 - 118
Recibido: 12 sept 2019
Aceptado: 21 oct 2019
DOI: https://doi.org/10.2478/acb-2019-0015
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© 2019 Greg Hutchings, Mariusz J. Nawrocki, Paul Mozdziak, Bartosz Kempisty, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Summary of Distinct CPC populations. List of CPCs discovered, species cell type identified in, cell lineages associated with cell type, cellular markers defining unique cell type, literature used to gather information
| CPC POPULATION | SPECIES | ASSOCIATED CELL LINEAGES | CELLULAR MARKERS | REFERENCES |
|---|---|---|---|---|
| c-Kit+ | Human, mouse, rat, dog, pig | Endothelial | c-Kit+, CD34-, CD45-, Sca-1+, Abcg2+, CD105+, CD166+, GATA4+, NKX2-5+/-, MEF2c+ | [9] [47] |
| Sca-1+ | Mouse | Endothelial, Smooth muscle | Sca-1+, CD105+, CD34-, CD45-, FLK1-, c-Kit+/-, GATA4+, NKX2-5+/-, MEF2C+ | [9] [47] |
| Epicardium-deri- ved cells | Human, mouse | Mesenchymal, fibroblast, smooth muscle | CD34+, c-Kit+/-, CD44+, CD90+, CD105+, CD46+ | [9] [47] |
| Cardiosphere-de- rived cells | Human, mouse, rat, dog, pig | Cardiomyocytes, endothelial, smooth muscle | CD31+, CD34+, c-Kit(low), Sca1+, CD45+, CD105+, Abcg2+ | [9] [47] |
| Islet-1+ | Mouse, rat, human | Second heart field, Cardiac neural crest | Isl-1+, CD31-, Sca-1-, c-Kit+/-, GATA4+, NKX2-5+ | [9] [47] |
| Side Population Cells | Mouse, rat | Cardiomyocyte, fibroblast, endothelial, smooth muscle | CD34+, CD45+, Abcg2+, Sca-1+, c-Kit+, NKX2-5-, GATA4- | [9] [47] |
| Cardiac colony forming unit fibroblasts | Mouse | Mesenchymal | PDGFR-a+, Sca-1+, CD31-, CD90+, c-Kit(low), CD45-, FLK1-, CD44+, CD29+, CD105+ | [9] [47] |