<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Humid indoor environments may be colonised by allergenic filamentous microfungi (moulds), <italic>Aspergillus</italic> spp., <italic>Penicillium</italic> spp., <italic>Cladosporium</italic> spp., and <italic>Alternaria</italic> spp. in particular. Mould-induced respiratory diseases are a worldwide problem. In the last two decades, mould allergens and glucans have been used as markers of indoor exposure to moulds. Recently, mould allergens Alt a 1 (<italic>Alternaria alternata</italic>) and Asp f 1 (<italic>Aspergillus fumigatus</italic>) have been analysed in various environments (residential and occupational) with enzyme-linked immunosorbent assays, which use monoclonal or polyclonal antibodies. Household Alt a 1 and Asp f 1 levels were usually under the limit of the method detection. By contrast, higher levels of mould allergens were found in environments with high levels of bioaerosols such as poultry farms and sawmills. Data on allergen Alt a 1 and Asp f 1 levels in agricultural settings may provide information on possible colonisation of respective moulds and point out to mould-related diseases in occupants.</p></abstract>

Humid indoor environments may be colonised by allergenic filamentous microfungi (moulds), Aspergillus spp., Penicillium spp., Cladosporium spp., and Alternaria spp. in particular. Mould-induced respiratory diseases are a worldwide problem. In the last two decades, mould allergens and glucans have been used as markers of indoor exposure to moulds. Recently, mould allergens Alt a 1 (Alternaria alternata) and Asp f 1 (Aspergillus fumigatus) have been analysed in various environments (residential and occupational) with enzyme-linked immunosorbent assays, which use monoclonal or polyclonal antibodies. Household Alt a 1 and Asp f 1 levels were usually under the limit of the method detection. By contrast, higher levels of mould allergens were found in environments with high levels of bioaerosols such as poultry farms and sawmills. Data on allergen Alt a 1 and Asp f 1 levels in agricultural settings may provide information on possible colonisation of respective moulds and point out to mould-related diseases in occupants.

Indoor Exposure to Mould Allergens

Institute for Medical Research and Occupational Health, Zagreb, Croatia

Archives of Industrial Hygiene and Toxicology

{"article-title":"Indoor Exposure to Mould Allergens"}

Humid indoor environments may be colonised by allergenic filamentous microfungi (moulds), Aspergillus spp., Penicillium spp., Cladosporium spp., and Alternaria...

Indoor Exposure to Mould Allergens

Publicado en línea: 25 dic 2011

Páginas: 371 - 380

DOI: https://doi.org/10.2478/10004-1254-62-2011-2126

Palabras clave
A. alternata, A. fumigatus,

This content is open access.

Indoor Exposure to Mould Allergens

Publicado en línea: 25 dic 2011

Páginas: 371 - 380

DOI: https://doi.org/10.2478/10004-1254-62-2011-2126

Palabras claveA. alternata, A. fumigatus,

This content is open access.

Palabras clave
A. alternata, A. fumigatus,