<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Acute lymphoblastic leukemia (ALL) is a malignant neoplasm of the lymphocyte precursor cells. Among adults it is a relatively rare neoplasm with a curability rate around 30% at 5 years. Currently, the diagnosis and classification of ALL is a multistep procedure that relies on the simultaneous application of multiple techniques that include: cytomorphology, immunophenotype and cytogenetic assays . Some of which have important clinical implications for both diagnosis and predicting response to specific treatment regimens, while the role of others is still to be defined. Over the years, several prognostic factors have been identified and today a risk stratification at diagnosis and during the follow -up is based on the characteristics of the leukemic cells.</p></abstract>

Acute lymphoblastic leukemia (ALL) is a malignant neoplasm of the lymphocyte precursor cells. Among adults it is a relatively rare neoplasm with a curability rate around 30% at 5 years. Currently, the diagnosis and classification of ALL is a multistep procedure that relies on the simultaneous application of multiple techniques that include: cytomorphology, immunophenotype and cytogenetic assays . Some of which have important clinical implications for both diagnosis and predicting response to specific treatment regimens, while the role of others is still to be defined. Over the years, several prognostic factors have been identified and today a risk stratification at diagnosis and during the follow -up is based on the characteristics of the leukemic cells.

Acute Lymphocytic Leukemia in Adults. Pathologic Features and Prognosis

Department of Hematology, University Emergency Hospital, Bucharest, Romania

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Acute Lymphocytic Leukemia in Adults. Pathologic Features and Prognosis"}

Acute lymphoblastic leukemia (ALL) is a malignant neoplasm of the lymphocyte precursor cells. Among adults it is a relatively rare neoplasm with a curability...

Acute Lymphocytic Leukemia in Adults. Pathologic Features and Prognosis

Publicado en línea: 07 oct 2015

Páginas: 33 - 38

Recibido: 12 feb 2015

DOI: https://doi.org/10.1515/rjim-2015-0004

Palabras clave
acute lymphoblastic leukaemia, prognostic factors, adults

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Acute Lymphocytic Leukemia in Adults. Pathologic Features and Prognosis

Publicado en línea: 07 oct 2015

Páginas: 33 - 38

Recibido: 12 feb 2015

DOI: https://doi.org/10.1515/rjim-2015-0004

Palabras claveacute lymphoblastic leukaemia, prognostic factors, adults

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Palabras clave
acute lymphoblastic leukaemia, prognostic factors, adults