Metastatic sebaceous cell carcinoma, review of the literature and use of electrochemotherapy as possible new treatment modality
Article Category: Research Article
Publicado en línea: 19 jul 2016
Páginas: 308 - 312
Recibido: 24 abr 2016
Aceptado: 14 may 2016
DOI: https://doi.org/10.1515/raon-2016-0039
© 2016 Radiol Oncol
This content is free.
Background
Metastatic extraorbital sebaceous carcinoma is a rare event that could involve the head and neck. The treatment of choice for the initial stage of the disease is surgery and/or radiotherapy. The treatment of recurrent or advanced disease is still controversial.
Material and methods
Extensive literature search was done, and the treatment options are discussed.
Results
Results. The literature search found several treatment modalities in use for the treatment of metastatic extraorbital sebaceous carcinoma. Electrochemotherapy was not included in the reported treatments. We used this technique for a man of 85 years old with a recurrent and locally metastatic extraorbital sebaceous carcinoma of the scalp. During the period of 8 months, two sessions of electrochemotherapy were employed, which resulted in an objective response of the tumour and good quality of life.
Conclusions
Electrochemotherapy has shown to be a interesting tools for treatment of metastatic extraorbital sebaceous carcinoma when other radical options are not available or convenient.