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Human therapeutic cloning, pitfalls and lack luster because of rapid developments in induced pluripotent stem cell technology


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1. Choumerianou DM, Dimitriou H, Kalmanti M. Stem cells: Promises versus limitations. Tissue engineering. Part B, Reviews. 2008; 14:53-60.10.1089/teb.2007.0216Open DOISearch in Google Scholar

2. Sidhu KS, Ryan JP, Tuch BE. Derivation of a new human embryonic stem cell line, endeavour-1, and its clonal propagation. Stem Cells Dev. 2008: 17:41-51.10.1089/scd.2007.0055Open DOISearch in Google Scholar

3. Munsie, MJ, Michalska AE, O’Brien CM, Trounson AO, Pera MF; Mountford PS. Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei. Curr Biol. 2000; 10:989-92.10.1016/S0960-9822(00)00648-5Open DOISearch in Google Scholar

4. Hochedlinger K, Jaenisch R. Nuclear transplantation, embryonic stem cells, and the potential for cell therapy. N Engl J Med. 2003; 349:275-96.10.1056/NEJMra03539712867612Search in Google Scholar

5. Eggan K, Baldwin K, Tackett M, Osborne J, Gogos J, Chess A, et al. Mice cloned from olfactory sensory neurons. Nature 2004; 428:44-9.10.1038/nature0237514990966Search in Google Scholar

6. Li J, Ishii T, Feinstein P, Mombaerts P. Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons. Nature. 2004; 428:393-9.10.1038/nature0243315042081Search in Google Scholar

7. Brambrink T, Hochedlinger K, Bell G, Jaenisch R. ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable. PNAS. 2006; 103:933-8.10.1073/pnas.0510485103134801916418286Open DOISearch in Google Scholar

8. Al-Shamy G, Ohta H, Wakayama T, Studer L. Therapeutic cloning in individual parkinsonian mice. Nature. 2008; 14:379-81.Search in Google Scholar

9. Tabar V, Tomishima M, Panagiotakos G, Wakayama S, Menon J, Chan B, et al. Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science. 2001; 292:740-3.10.1126/science.105939911326103Search in Google Scholar

10. Chung Y, Bishop CE, Treff NR, Walker SJ, Sandler VM, Becker S, et al. Reprogramming of human somatic cells using human and animal oocytes. Cloning Stem Cells. 2009; 11:213-23.10.1089/clo.2009.000419186982Open DOISearch in Google Scholar

11. Byrne JA, Pedersen DA, Clepper LL, Nelson M, Sanger WG, Gokhale S, et al. Producing primate embryonic stem cells by somatic cell nuclear transfer. Nature. 2007; 450:497-502.10.1038/nature0635718004281Search in Google Scholar

12. Gurdon J. Primate therapeutic cloning in practice. Nature. 2008; 26:64-5.Search in Google Scholar

13. Bortvin A, Eggan K, Skaletsky H, Akutsu H, Berry DL, Yanagimachi R, et al. Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. Development. 2003; 130:1673-80.10.1242/dev.00366Search in Google Scholar

14. Blelloch R, Wang Z, Meissner A, Pollard S, Smith A, Jaenisch R. Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus. Stem Cells. 2006; 24:2007-13.10.1634/stemcells.2006-0050Open DOISearch in Google Scholar

15. Wakayama T, Yanagimachi R. Mouse cloning with nucleus donor cells of different age and type. Mol Reprod Dev. 2001; 58:376-83.10.1002/1098-2795(20010401)58:4<376::AID-MRD4>3.0.CO;2-LOpen DOISearch in Google Scholar

16. Humpherys D, Eggan K, Akutsu H, Friedman A, Hochedlinger K, Yanagimachi R, et al. Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei. Proc Natl Acad Sci USA. 2002; 99:12889-94.10.1073/pnas.192433399Search in Google Scholar

17. Ng RK, JB Gurdon. Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer. Proc Natl Acad Sci USA. 2005; 102:1957-62.10.1073/pnas.0409813102Open DOISearch in Google Scholar

18. Kohda T, Inoue K, Ogonuki N, Miki H, Naruse M, Kaneko-Ishino T, et al. Variation in gene expression and aberrantly regulated chromosome regions in cloned mice. Biol Reprod. 2005; 73:1302-11.10.1095/biolreprod.105.044958Search in Google Scholar

19. Jaenisch R. Human cloning-the science and ethics of nuclear transplantation. N Engl J Med. 2004; 351: 2787-91.10.1056/NEJMp048304Search in Google Scholar

20. Hall VJ, Compton D, Stojkovic P, Nesbitt M, Herbert M, Murdoch A, et al. Developmental competence of human in vitro aged oocytes as host cells for nuclear transfer. Hum Reprod. 2007; 22:52-62.10.1093/humrep/del345Open DOISearch in Google Scholar

21. Egli D, Chen AE, Saphier G, Powers D, Alper M, Katz K, et al. Impracticality of egg donor recruitment in the absence of compensation. Stem Cell. 2011; 9: 293-4.10.1016/j.stem.2011.08.002Search in Google Scholar

22. Stojkovic M, Stojkovic P, Leary C, Hall VJ, Armstrong L, Herbert M, et al. Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes. Reprod Biomed Online. 2005; 11:226-31.10.1016/S1472-6483(10)60962-5Open DOISearch in Google Scholar

23. Tachibana M, Amato P, Sparman M, Gutierrez NM, Tippner-Hedges R, Ma H, et al. Human embryonic stem cells derived by somatic cell nuclear transfer. Cell. 2013;153:1228-38.10.1016/j.cell.2013.05.006377278923683578Search in Google Scholar

24. French AJ, Adams CA, Anderson LS, Kitchen JR, Hughes MR, SH Wood. Development of human cloned blastocysts following somatic cell nuclear transfer with adult fibroblasts. Stem cells. 2008; 26:485-93.10.1634/stemcells.2007-025218202077Open DOISearch in Google Scholar

25. Zhao J, Ross JW, Hao Y, Spate LD, Walters EM, Samuel MS, et al. Significant improvement in cloning efficiency of an inbred miniature pig by histone deacetylase inhibitor treatment after somatic cell nuclear transfer. Biol Reprod. 2009; 81:525-30.10.1095/biolreprod.109.077016273198019386991Open DOISearch in Google Scholar

26. Zhang J, Wilson GF, Soerens AG, Koonce CH, Yu JY, Palecek SP, et al. Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ Res. 2009; 104:30-41.10.1161/CIRCRESAHA.108.192237274133419213953Open DOISearch in Google Scholar

27. Cai J, Yang M, Poremsky E, Kidd S, Schneider JS, Iacovitti L. Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA lesioned rats. Stem Cells Dev. 2010; 19: 1017-23. 10.1089/scd.2009.0319313524819824823Open DOISearch in Google Scholar

28. Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, et al. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells. 2009; 27:806-11.10.1002/stem.31289590919350680Open DOISearch in Google Scholar

29. Zhang J, Wilson GF, Soerens AG, Koonce CH, Yu JY, Palecek SP, et al. Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ Res. 2009; 104:30-41.10.1161/CIRCRESAHA.108.192237Open DOISearch in Google Scholar

30. Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K. Induced pluripotent stem cells generated without viral integration. Science. 2008; 322:945-9.10.1126/science.1162494398790918818365Search in Google Scholar

31. Yu J, Hu K, Smuga-Otto K, Tian SL, Stewart R, Slukvin II, et al. Human induced pluripotent stem cells free of vector and transgene sequences. Science. 2009; 324:1266.10.1126/science.1172482275805319325077Search in Google Scholar

32. Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell. 2009; 4:381-4.10.1016/j.stem.2009.04.00519398399Open DOISearch in Google Scholar

33. Obokata H, Wakayama T, Sasai Y, Kojima K, Vacanti MP, Niwa H, et al. Stimulus-triggered fate conversion of somatic cells into pluripotency. Nature. 2014; 505: 641-58.10.1038/nature1296824476887Search in Google Scholar

34. Obokata H, Sasai Y, Niwa H, Kadota M, Andrabi M, Takata N, et al. Bidirectional developmental potential in reprogrammed cells with acquired pluripotency. Nature Lett. 2014; 505:676-86.10.1038/nature1296924476891Search in Google Scholar

35. Huangfu D, Maehr R, Guo WJ, Eijkelenboom A, Snitow M, Chen AE, et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotech. 2008; 26: 795-7.10.1038/nbt1418633464718568017Open DOISearch in Google Scholar

36. Shi Y, Do JT, Desponts C, Hahm HS, Scholer HR, Ding S. A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell. 2008; 3:119.10.1016/j.stem.2008.06.003Open DOISearch in Google Scholar

37. Wilson KD, Venkatasubrahmanyam S, Jia F, Sun N, Butte AJ, JC Wu. MicroRNA profiling of humaninduced pluripotent stem cells. Stem Cells Dev. 2009; 18:749-58.10.1089/scd.2008.0247313518119284351Open DOISearch in Google Scholar

38. Hu BY, Weick JP, Yu J, Ma LX, Zhang XQ, Thomson JA, et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc Natl Acad Sci USA. 2010; 107:4335-40.10.1073/pnas.0910012107284009720160098Search in Google Scholar

39. Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, et al. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell. 2010; 7:521-31.10.1016/j.stem.2010.07.01720887957Open DOISearch in Google Scholar

40. Marion RM, Strati K, Li H, Murga M, Blanco R, Ortega S, et al. A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature. 2009; 460:1149-53.10.1038/nature08287362408919668189Search in Google Scholar

41. Zwaka TP. What comes after iPS? Nature Reports Stem Cells. 2008, doi:10.1038/stemcells.2008.54.Search in Google Scholar

42. White YAR, Woods DC, Takai Y, Ishihara O, Seki H, JL Tilly. Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women. Nature. 2012; 18:413-22.Search in Google Scholar

43. Noggle S, Fung HL, Gore A, Martinez H, Satriani KC, Prosser R, et al. Human oocytes reprogram somatic cells to a pluripotent state. Nature. 2011; 478:70-7. 10.1038/nature1039721979046Search in Google Scholar

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Sprache:
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Medizin, Gesundheitsfachberufe, Vorklinische Medizin, Grundlagenmedizin, andere, Klinische Medizin