<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Aim</bold>: The aim of this study is to identify correlations between total antioxidant status values of mothers and their infants and compare these values in accordance to the presence or absence of intrauterine growth restriction.<bold>Material and methods</bold>: This is a prospective, comparative study performed over a period of 3 years on a number of 52 infants and their mothers. Thirty-six of them had intrauterine growth restriction and 16 were appropriate for their gestational age and were used for comparative purposes. General information regarding the mother, infant and pregnancy were recorded. In addition, total antioxidant status was assessed from blood samples, taken right before delivery from mothers and from the cord blood in infants.<bold>Results</bold>: We found significant differences between total antioxidant status both between mothers and neonates with IUGR (intrauterine growth restriction) versus without IUGR (p=0.018, and p&lt;0.001, respectively). In addition, in both groups, there was a significant direct correlation between maternal and neonatal values of serum total antioxidant status (TAS) (p&lt;0.001).In <bold>conclusion</bold>, we can say that TAS values, as an important marker of the oxidative status of patients, are correlated with the presence of IUGR and values recorded from blood samples of the mother may be predictive for the oxidative status of the infant, thus of IUGR.</abstract>

Aim: The aim of this study is to identify correlations between total antioxidant status values of mothers and their infants and compare these values in accordance to the presence or absence of intrauterine growth restriction.Material and methods: This is a prospective, comparative study performed over a period of 3 years on a number of 52 infants and their mothers. Thirty-six of them had intrauterine growth restriction and 16 were appropriate for their gestational age and were used for comparative purposes. General information regarding the mother, infant and pregnancy were recorded. In addition, total antioxidant status was assessed from blood samples, taken right before delivery from mothers and from the cord blood in infants.Results: We found significant differences between total antioxidant status both between mothers and neonates with IUGR (intrauterine growth restriction) versus without IUGR (p=0.018, and p<0.001, respectively). In addition, in both groups, there was a significant direct correlation between maternal and neonatal values of serum total antioxidant status (TAS) (p<0.001).In conclusion, we can say that TAS values, as an important marker of the oxidative status of patients, are correlated with the presence of IUGR and values recorded from blood samples of the mother may be predictive for the oxidative status of the infant, thus of IUGR.

Total antioxidant status as marker of oxidative stress in infants with intrauterine growth restriction

”Grigore T. Popa” University of Medicine and Pharmacy

Revista Romana de Medicina de Laborator

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Aim: The aim of this study is to identify correlations between total antioxidant status values of mothers and their infants and compare these values in...

Total antioxidant status as marker of oxidative stress in infants with intrauterine growth restriction

Online veröffentlicht: 04. Mai 2020

Seitenbereich: 145 - 152

Eingereicht: 19. Aug. 2019

Akzeptiert: 28. Jan. 2020

DOI: https://doi.org/10.2478/rrlm-2020-0013

Schlüsselwörter
neonatal, total oxidative status, intrauterine growth restriction, oxidative status

© 2020 Șadiye-Ioana Scripcariu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Total antioxidant status as marker of oxidative stress in infants with intrauterine growth restriction

Online veröffentlicht: 04. Mai 2020

Seitenbereich: 145 - 152

Eingereicht: 19. Aug. 2019

Akzeptiert: 28. Jan. 2020

DOI: https://doi.org/10.2478/rrlm-2020-0013

Schlüsselwörterneonatal, total oxidative status, intrauterine growth restriction, oxidative status

© 2020 Șadiye-Ioana Scripcariu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
neonatal, total oxidative status, intrauterine growth restriction, oxidative status