<abstract xmlns="http://www.w3.org/1999/xhtml">

<p> The aim of the study was to assess the microvessel density based on the analysis of the expression of the CD31, VEGF, and LIMS-1 proteins in canine mast cell tumours. The study was conducted on 60 mastocytomas; 16 cases were classified as the grade I, 26 as the grade II, and 18 as the grade III. Statistical analysis showed a positive correlation only between the grade of the tumour and the expression of LIMS-1. In conclusion, LIMS-1 could be successfully used as a prognostic endothelial cell marker in mast cell tumour. CD31 may be a useful marker, but further examinations are necessary. VEGF is not recommended</p>
</abstract>

The aim of the study was to assess the microvessel density based on the analysis of the expression of the CD31, VEGF, and LIMS-1 proteins in canine mast cell tumours. The study was conducted on 60 mastocytomas; 16 cases were classified as the grade I, 26 as the grade II, and 18 as the grade III. Statistical analysis showed a positive correlation only between the grade of the tumour and the expression of LIMS-1. In conclusion, LIMS-1 could be successfully used as a prognostic endothelial cell marker in mast cell tumour. CD31 may be a useful marker, but further examinations are necessary. VEGF is not recommended

Immunohistochemical evaluation of neoangiogenesis in canine mast cell tumours

Department of Pathology, Division of Pathomorphology and Veterinary Forensics

Faculty of Veterinary Medicine Wroclaw University of Environmental and Life Sciences

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Immunohistochemical evaluation of neoangiogenesis in canine mast cell tumours"}

The aim of the study was to assess the microvessel density based on the analysis of the expression of the CD31, VEGF, and LIMS-1 proteins in canine mast cell...

Immunohistochemical evaluation of neoangiogenesis in canine mast cell tumours

Online veröffentlicht: 03. Juli 2015

Seitenbereich: 247 - 253

Eingereicht: 19. Dez. 2014

Akzeptiert: 03. Juni 2015

DOI: https://doi.org/10.1515/bvip-2015-0037

© 2015 National Veterinary Research Institute in Pulawy

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.