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Clinical outcomes and surgical preferences for breast-conserving surgery and mastectomy: a propensity score-matched analysis


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Figure 1

Flow diagram of the study sample.
Flow diagram of the study sample.

Figure 2

Residual variance in unmatched and matched samples.
Residual variance in unmatched and matched samples.

Propensity score matching

Mastectomy (n = 209)BCS (n = 356)P
Age0.005
        21–302 (0.96%)3 (0.84%)
        31–4020 (9.57%)35 (9.83%)
        41–5050 (23.92%)131 (36.80%)
        51–6076 (36.36%)110 (30.90%)
        61–7036 (17.22%)61 (17.13%)
        71–8021 (10.05%)14 (3.93%)
        81–903 (1.44%)2 (0.56%)
        91–1001 (0.48%)0 (0.00%)
Menopause1371960.021
Surgeon0.001
        A99 (47.37%)171 (48.03%)
        B38 (18.18%)126 (35.39%)
        C46 (22.01%)15 (4.21%)
        D15 (7.18%)36 (10.11%)
        E9 (4.31%)5 (1.40%)
        F2 (0.96%)3 (0.84%)
Clinical tumor size2.481.480.001
(cm)
Hormonal status positive148 (n = 200)264 (n = 336)0.225
HER-2 positive42 (n = 180)59 (n = 278)0.503
Tumor grade0.002
        122 (10.52%)82 (23.03%)
        285 (40.67%)134 (37.64%)
        376 (36.36%)107 (30.06%)
        Unknown26 (12.44%)33 (9.27%)
Tumor stage<0.001
        019 (9.09%)36 (10.11%)
        140 (19.14%)149 (41.85%)
        2113 (54.07%)148 (41.57%)
        336 (17.22%)20 (5.62%)
        Unknown1 (0.48%)5 (0.84%)
Disease-free survival (months)54650.9950
Overall survival (months)59720.9988

Baseline characteristics

Mastectomy (n = 260)BCS (n = 454)P
Age0.010
        21–303 (1.15%)3 (0.66%)
        31–4021 (8.08%)41 (9.03%)
        41–5069 (26.54%)167 (36.78%)
        51–6093 (35.77%)143 (31.50%)
        61–7042 (16.15%)75 (16.52%)
        71–8026 (10.00%)22 (4.85%)
        81–905 (1.92%)3 (0.66%)
        91–1001 (0.38%)0 (0.00%)
Menopause1652590.097
Surgeon<0.001
        A127 (48.85%)209 (46.04%)
        B56 (21.54%)178 (39.21%)
        C47 (18.08%)17 (3.74%)
        D18 (6.92%)42 (9.25%)
        E9 (3.46%)5 (1.10%)
        F3 (1.15%)3 (0.66%)
Avg. clinical tumor2.451.48<0.001
size (cm)
Hormonal status positive1893390.554
HER-2 positive51770.133
Tumor grade<0.001
        132 (12.31%)113 (24.89%)
        2106 (40.77%)171 (37.67%)
        386 (33.08%)130 (28.63%)
        Unknown36 (13.85%)40 (8.81%)
Tumor stage<0.001
        021 (8.08%)49 (10.79%)
        149 (18.85%)204 (44.93%)
        2132 (50.77%)170 (37.44%)
        356 (21.54%)28 (6.17%)
        Unknown2 (0.77%)3 (0.66%)
Recurrence35630.877
Death10160.825
eISSN:
1875-855X
Sprache:
Englisch
Zeitrahmen der Veröffentlichung:
6 Hefte pro Jahr
Fachgebiete der Zeitschrift:
Medizin, Gesundheitsfachberufe, Vorklinische Medizin, Grundlagenmedizin, andere, Klinische Medizin