This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Vincent JL, Opal SM, Marshall JC, Tracey KJ. Sepsis definitions: time for change. Lancet. 2013; 281:774-5.VincentJLOpalSMMarshallJCTraceyKJ.Sepsis definitions: time for changeLancet.2013281774510.1016/S0140-6736(12)61815-7Search in Google Scholar
Reinhart K, Daniels R, Machado FR. The burden of sepsis: a call to action in support of World Sepsis Day 2013. Rev Bras Ter Intensiva. 2013; 25:3-5.ReinhartKDanielsRMachadoFR.The burden of sepsis: a call to action in support of World Sepsis Day 2013Rev Bras Ter Intensiva.2013253510.1016/j.jcrc.2013.04.01223747158Search in Google Scholar
Tiru B, DiNino EK, Orenstein A, Mailloux PT, Pesaturo A, Gupta A, et al. The economic and humanistic burden of severe sepsis. Pharmacoeconomics. 2015; 33:925-37.2593521110.1007/s40273-015-0282-yTiruBDiNinoEKOrensteinAMaillouxPTPesaturoAGuptaAThe economic and humanistic burden of severe sepsisPharmacoeconomics.2015339253725935211Search in Google Scholar
Cohen J. The immunopathogenesis of sepsis. Nature. 2002; 420:885-91.1249096310.1038/nature01326CohenJ.The immunopathogenesis of sepsisNature.20024208859112490963Search in Google Scholar
Stojković D, Petrović J, Soković M, Glamoćlija J, Kukić-Marković J, Petrović S. In situ antioxidant and antimicrobial activities of naturally occurring caffeic acid, p-coumaric acid and rutin, using food systems. J Sci Food Agric. 2013; 93:3205-8.10.1002/jsfa.615623553578StojkovićDPetrovićJSokovićMGlamoćlijaJKukić-MarkovićJPetrovićS.In situ antioxidant and antimicrobial activities of naturally occurring caffeic acid, p-coumaric acid and rutin, using food systemsJ Sci Food Agric.2013933205823553578Open DOISearch in Google Scholar
Guven M, Yuksel Y, Sehitoglu MH, Tokmak M, Aras AB, Akman T, et al. The effect of coumaric acid on ischemia–reperfusion injury of sciatic nerve in rats. Inflammation. 2015; 38:2124-32.10.1007/s10753-015-0195-026049410GuvenMYukselYSehitogluMHTokmakMArasABAkmanTThe effect of coumaric acid on ischemia–reperfusion injury of sciatic nerve in ratsInflammation.20153821243226049410Open DOISearch in Google Scholar
Thakur K, Kalia S, Sharma N, Pathania D. Laccase-mediated biografting of p-coumaric acid for development of antibacterial and hydrophobic properties in coconut fibers. J Mol Catal B Enzym. 2015; 122:289-95.10.1016/j.molcatb.2015.10.002ThakurKKaliaSSharmaNPathaniaD.Laccase-mediated biografting of p-coumaric acid for development of antibacterial and hydrophobic properties in coconut fibersJ Mol Catal B Enzym.201512228995Open DOISearch in Google Scholar
Pragasam SJ, Venkatesan V, Rasool MK. Immunomodulatory and anti-inflammatory effect of p-coumaric acid, a common dietary polyphenol on experimental inflammation in rats. Inflammation. 2013; 36:169-76.2292300310.1007/s10753-012-9532-8PragasamSJVenkatesanVRasoolMK.Immunomodulatory and anti-inflammatory effect of p-coumaric acid, a common dietary polyphenol on experimental inflammation in ratsInflammation.2013361697622923003Search in Google Scholar
Landete JM. Ellagitannins, ellagic acid and their derived metabolites: a review about source, metabolism, functions and health. Food Res Int. 2011; 44:1150-60.10.1016/j.foodres.2011.04.027LandeteJM.Ellagitannins, ellagic acid and their derived metabolites: a review about source, metabolism, functions and healthFood Res Int.201144115060Open DOISearch in Google Scholar
García-Niño WR, Zazueta C. Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection. Pharmacol Res. 2015; 97: 84-103.10.1016/j.phrs.2015.04.00825941011García-NiñoWRZazuetaC.Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protectionPharmacol Res.2015978410325941011Open DOISearch in Google Scholar
Akkoyun HT, Karadeniz A. Investigation of the protective effect of ellagic acid for preventing kidney injury in rats exposed to nicotine during the fetal period. Biotech Histochem. 2016; 91:108-15.10.3109/10520295.2015.107891026529089AkkoyunHTKaradenizA.Investigation of the protective effect of ellagic acid for preventing kidney injury in rats exposed to nicotine during the fetal periodBiotech Histochem.20169110815Open DOISearch in Google Scholar
Singer M, De Santis V, Vitale D, Jeffcoate W. Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammation. Lancet. 2004; 364:545-8.1530220010.1016/S0140-6736(04)16815-3SingerMDe SantisVVitaleDJeffcoateW.Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammationLancet.20043645458Search in Google Scholar
Heine H, Rietschel ET, Ulmer AJ. The biology of endotoxin. Mol Biotechnol. 2001; 19:279-96.1172162410.1385/MB:19:3:279HeineHRietschelETUlmerAJ.The biology of endotoxinMol Biotechnol.20011927996Search in Google Scholar
Wendel A. Reactive oxygen species, antiproteases, and cytokines in sepsis. Klin Wochenschr. 1991; 69: 969-74.10.1007/BF016451411798293WendelA.Reactive oxygen species, antiproteases, and cytokines in sepsisKlin Wochenschr.19916996974Open DOISearch in Google Scholar
Kaymak C, Basar H, Sardas S. Reactive oxygen species (Ros) generation in sepsis. FABAD J Pharm Sci. 2011; 36:41-7.KaymakCBasarHSardasS.Reactive oxygen species (Ros) generation in sepsisFABAD J Pharm Sci.201136417Search in Google Scholar
Galley HF. Oxidative stress and mitochondrial dysfunction in sepsis. Br J Anaesth. 2011; 107:57-64.2159684310.1093/bja/aer093GalleyHF.Oxidative stress and mitochondrial dysfunction in sepsisBr J Anaesth.20111075764Search in Google Scholar
Luceri C, Guglielmi F, Lodovici M, Giannini L, Messerini L, Dolara P. Plant phenolic 4-coumaric acid protects against intestinal inflammation in rats. Scand J Gastroenterol 2004; 39:1128-33.15545172LuceriCGuglielmiFLodoviciMGianniniLMesseriniLDolaraP.Plant phenolic 4-coumaric acid protects against intestinal inflammation in ratsScand J Gastroenterol200439112833Search in Google Scholar
Kilani-Jaziri S, Mokdad-Bzeouich I, Krifa M, Nasr N, Ghedira K, Chekir-Ghedira L. Immunomodulatory and cellular anti-oxidant activities of caffeic, ferulic, and p-coumaric phenolic acids: a structure–activity relationship study. Drug Chem Toxicol. 2016; 18:1-9.Kilani-JaziriSMokdad-BzeouichIKrifaMNasrNGhediraKChekir-GhediraL.Immunomodulatory and cellular anti-oxidant activities of caffeic, ferulic, and p-coumaric phenolic acids: a structure–activity relationship studyDrug Chem Toxicol.2016181910.1080/01480545.2016.1252919Search in Google Scholar
Ben-Shaul V, Lomnitski L, Nyska A, Zurovsky Y, Bergman M, Grossman S. The effect of natural antioxidants, NAO and apocynin, on oxidative stress in the rat heart following LPS challenge. Toxicol Lett. 2001; 123:1-10.10.1016/S0378-4274(01)00369-111514100Ben-ShaulVLomnitskiLNyskaAZurovskyYBergmanMGrossmanS.The effect of natural antioxidants, NAO and apocynin, on oxidative stress in the rat heart following LPS challengeToxicol Lett.2001123110Open DOISearch in Google Scholar
Liu CJ, Lin JY. Anti-inflammatory effects of phenolic extracts from strawberry fruits on cytokine secretion profiles using mouse primary splenocytes and peritoneal macrophages. Int Immunopharmacol. 2013; 16:165-70.10.1016/j.intimp.2013.03.03223590821LiuCJLinJY.Anti-inflammatory effects of phenolic extracts from strawberry fruits on cytokine secretion profiles using mouse primary splenocytes and peritoneal macrophagesInt Immunopharmacol.20131616570Open DOISearch in Google Scholar
Mo J, Panichayupakaranant P, Kaewnopparat N, Nitiruangjaras A, Reanmongkol W. Topical anti-inflammatory and analgesic activities of standardized pomegranate rind extract in comparison with its marker compound ellagic acid in vivo. J Ethnopharmacol. 2013; 148:901-8.2374305710.1016/j.jep.2013.05.040MoJPanichayupakaranantPKaewnopparatNNitiruangjarasAReanmongkolW.Topical anti-inflammatory and analgesic activities of standardized pomegranate rind extract in comparison with its marker compound ellagic acid in vivoJ Ethnopharmacol.20131489018Search in Google Scholar
da Silva AO, Damaceno Alves A, Almeida DA, Balogun SO, de Oliveira RG, Aires Aguiar A, et al. Evaluation of anti-inflammatory and mechanism of action of extract of Macrosiphonia longiflora (Desf.) Müll. Arg. J Ethnopharmacol. 2014; 154:319-29.10.1016/j.jep.2014.03.017da SilvaAODamaceno AlvesAAlmeidaDABalogunSOde OliveiraRGAires AguiarAEvaluation of anti-inflammatory and mechanism of action of extract of Macrosiphonia longiflora (Desf.) MüllArg. J Ethnopharmacol.201415431929Open DOISearch in Google Scholar
Mansouri MT, Hemmati AA, Naghizadeh B, Mard SA, Rezaie A, Ghorbanzadeh B. A study of the mechanisms underlying the anti-inflammatory effect of ellagic acid in carrageenan-induced paw edema in rats. Indian J Pharmacol. 2015; 47:292-8.2606936710.4103/0253-7613.157127MansouriMTHemmatiAANaghizadehBMardSARezaieAGhorbanzadehB.A study of the mechanisms underlying the anti-inflammatory effect of ellagic acid in carrageenan-induced paw edema in ratsIndian J Pharmacol.2015472928Search in Google Scholar
Pragasam SJ, Rasool M. Dietary component p-coumaric acid suppresses monosodium urate crystal-induced inflammation in rats. Inflamm Res. 2013; 62:489-98.10.1007/s00011-013-0602-723420453PragasamSJRasoolM.Dietary component p-coumaric acid suppresses monosodium urate crystal-induced inflammation in ratsInflamm Res.20136248998Open DOISearch in Google Scholar
Prasanna N, Krishnan DN, Rasool M. Sodium arsenite-induced cardiotoxicity in rats: protective role of p-coumaric acid, a common dietary polyphenol. Toxicol Mech Methods. 2013; 23:255-62.10.3109/15376516.2012.74811623194016PrasannaNKrishnanDNRasoolM.Sodium arsenite-induced cardiotoxicity in rats: protective role of p-coumaric acid, a common dietary polyphenolToxicol Mech Methods.20132325562Open DOISearch in Google Scholar
Rafieirad M, Ghasemzadeh-Dehkordi K. Effect of ellagic acid on oxidative stress duo to brain ischemia/hypoperfusion. J Herbal Drugs. 2014; 5:1-6.RafieiradMGhasemzadeh-DehkordiK.Effect of ellagic acid on oxidative stress duo to brain ischemia/hypoperfusionJ Herbal Drugs.2014516Search in Google Scholar
Guo F, Yan CY. Effect of SecinH3 on lung injury induced by sepsis of rats. Asian Pac J Trop Med. 2015; 8:1049-54.10.1016/j.apjtm.2015.11.00426706678GuoFYanCY.Effect of SecinH3 on lung injury induced by sepsis of ratsAsian Pac J Trop Med.20158104954Open DOISearch in Google Scholar
Lowry OH, Rosebrough NJ, Farr A, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951; 193:265-75.14907713LowryOHRosebroughNJFarrARandallRJ.Protein measurement with the Folin phenol reagentJ Biol Chem.19511932657510.1016/S0021-9258(19)52451-6Search in Google Scholar
Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG. Selenium: biochemical role as a component of glutathione peroxidase. Science. 1973; 179:588-90.10.1126/science.179.4073.5884686466RotruckJTPopeALGantherHESwansonABHafemanDGHoekstraWG.Selenium: biochemical role as a component of glutathione peroxidaseScience.197317958890Open DOISearch in Google Scholar
Sun Y, Oberley LW, Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem. 1988; 34: 497-500.3349599SunYOberleyLWLiY.A simple method for clinical assay of superoxide dismutaseClin Chem.19883449750010.1093/clinchem/34.3.497Search in Google Scholar
Sinha AK. Colorimetric assay of catalase. Anal Biochem. 1972; 47:389-94.10.1016/0003-2697(72)90132-74556490SinhaAK.Colorimetric assay of catalaseAnal Biochem.19724738994Open DOISearch in Google Scholar
Stucchi AF, Shofer S, Leeman S, Materne O, Beer E, McClung J, et al. NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats. Am J Physiol Gastrointest Liver Physiol. 2000; 279:G1298-306.1109395410.1152/ajpgi.2000.279.6.G1298StucchiAFShoferSLeemanSMaterneOBeerEMcClungJNK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in ratsAm J Physiol Gastrointest Liver Physiol.2000279G1298306Search in Google Scholar
Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979; 95:351-8.10.1016/0003-2697(79)90738-336810OhkawaHOhishiNYagiK.Assay for lipid peroxides in animal tissues by thiobarbituric acid reactionAnal Biochem.1979953518Open DOISearch in Google Scholar
Saba, Khan S, Parvez S, Chaudhari B, Ahmad F, Anjum S, et al. Ellagic acid attenuates bleomycin and cyclophosphamide-induced pulmonary toxicity in Wistar rats. Food Chem Toxicol. 2013; 58:210-219.2360338110.1016/j.fct.2013.03.046Saba, KhanSParvezSChaudhariBAhmadFAnjumSEllagic acid attenuates bleomycin and cyclophosphamide-induced pulmonary toxicity in Wistar ratsFood Chem Toxicol.20135821021923603381Search in Google Scholar
Kelly KA, Hill MR, Youkhana K, Wanker F, Gimble JM. Dimethyl sulfoxide modulates NF-κB and cytokine activation in lipopolysaccharide-treated murine macrophages. Infect Immun. 1994; 62: 3122-8.8039880KellyKAHillMRYoukhanaKWankerFGimbleJM.Dimethyl sulfoxide modulates NF-κB and cytokine activation in lipopolysaccharide-treated murine macrophagesInfect Immun.1994623122810.1128/iai.62.8.3122-3128.19943029368039880Search in Google Scholar
Li YM, Wang HB, Zheng JG, Bai XD, Zhao ZK, Li JY, Hu S. Dimethyl sulfoxide inhibits zymosan-induced intestinal inflammation and barrier dysfunction. World J Gastroenterol. 2015; 21:10853-65.10.3748/wjg.v21.i38.1085326478676LiYMWangHBZhengJGBaiXDZhaoZKLiJYHuS.Dimethyl sulfoxide inhibits zymosan-induced intestinal inflammation and barrier dysfunctionWorld J Gastroenterol.2015211085365460058626478676Open DOISearch in Google Scholar
Colucci M, Maione F, Bonito MC, Piscopo A, Di Giannuario A, Pieretti S. New insights of dimethyl sulphoxide effects (DMSO) on experimental in vivo models of nociception and inflammation. Pharmacol Res. 2008; 57:419-25.1850827810.1016/j.phrs.2008.04.004ColucciMMaioneFBonitoMCPiscopoADi GiannuarioAPierettiS.New insights of dimethyl sulphoxide effects (DMSO) on experimental in vivo models of nociception and inflammationPharmacol Res.2008574192518508278Search in Google Scholar
Tsung YC, Chung CY, Wan HC, Chang YY, Shih PC, Hsu HS, et al. Dimethyl sulfoxide attenuates acute lung injury induced by hemorrhagic shock/resuscitation in rats. Inflammation. 2017; 40:555-65.10.1007/s10753-016-0502-428028757TsungYCChungCYWanHCChangYYShihPCHsuHSDimethyl sulfoxide attenuates acute lung injury induced by hemorrhagic shock/resuscitation in ratsInflammation.2017405556528028757Open DOISearch in Google Scholar
Marchetti C, Mezzaroma E, Toldo S. Effects of dimethyl sulfoxide on the NLRP3 inflammasome. Immunobiol. 2015; 220:1030.10.1016/j.imbio.2015.02.003MarchettiCMezzaromaEToldoS.Effects of dimethyl sulfoxide on the NLRP3 inflammasomeImmunobiol.2015220103025743943Open DOISearch in Google Scholar
